Seismic Assessment and Performance of Nonstructural Components Affected by Structural Modeling

Jieun Hur,Eric Althoff,Halil Sezen,Richard Denning,Tunc Aldemir 한국원자력학회 2017 Nuclear Engineering and Technology Vol.49 No.2

Seismic probabilistic risk assessment (SPRA) requires a large number of simulations toevaluate the seismic vulnerability of structural and nonstructural components in nuclearpower plants. The effect of structural modeling and analysis assumptions on dynamicanalysis of 3D and simplified 2D stick models of auxiliary buildings and the attachednonstructural components is investigated. Dynamic characteristics and seismic performanceof building models are also evaluated, as well as the computational accuracy of themodels. The presented results provide a better understanding of the dynamic behavior andseismic performance of auxiliary buildings. The results also help to quantify the impact ofuncertainties associated with modeling and analysis of simplified numerical models ofstructural and nonstructural components subjected to seismic shaking on the predictedseismic failure probabilities of these systems.

The antitumor effect of a thermosensitive polymeric hydrogel containing paclitaxel in a peritoneal carcinomatosis model.

Yu, Jieun,Lee, Hyuk-Joon,Hur, Keun,Kwak, Mi Kyung,Han, Tae Su,Kim, Woo Ho,Song, Soo-Chang,Yanagihara, Kazuyoshi,Yang, Han-Kwang M. Nijhoff ; Kluwer Academic Publishers 2012 Investigational new drugs Vol.30 No.1

<P>The prognosis of peritoneal carcinomatosis is regarded as poor because safe, effective therapeutic modalities are lacking. Intraperitoneal chemotherapy is one treatment option, involving the delivery of a high concentration of chemotherapeutic drugs into the abdominal cavity, but the severe side effects associated with such treatment are a major obstacle in clinical application. We evaluated the anti-cancer effects of intraperitoneal delivery of a thermosensitive polymeric hydrogel containing chemotherapeutics in an animal model of carcinomatosis. The progress of peritoneal carcinomatosis, introduced by injecting a luciferase-transfected human gastric cancer cell line (HSC44Luc) into the peritoneal cavity of nude mice, was quantitatively evaluated by in vivo bioluminescence imaging. Three days after intraperitoneal (IP) injection of HSC44Luc cells, treatment solutions were injected into the peritoneal cavity. Mice were categorized into four groups depending on treatment method; these were (1) a control PBS group (n?=?5), (2) a hydrogel-only group (n?=?5), (3) a paclitaxel solution (30?mg/kg) group (n?=?3), and (4) a hydrogel-with-paclitaxel (15?mg/kg) group (n?=?5). Quantitative photon counting was performed weekly in each animal. Mice were sacrificed on the 5th or 28th day after treatment, for pathologic evaluation. In vivo bioluminescence imaging showed that photon counts in the hydrogel-with-paclitaxel and paclitaxel solution groups were significantly lower than in the PBS group over the entire experimental period. Although neither group of responding mice showed any peritoneal nodules on the 28th day after treatment, only the paclitaxel solution group exhibited dilated edematous changes in the intestine; these side effects were absent in animals treated with hydrogel-with-paclitaxel group. In conclusion, a thermosensitive hydrogel containing paclitaxel may be a safe and effective treatment option for peritoneal carcinomatosis.</P>

Disproportionate Patterns of Retaliatory Antidumping Filings by Developing and Developed Countries

Jung Hur,Jieun Jung 한국경제연구학회 2013 Korea and the World Economy Vol.14 No.3

Using global antidumping cases for 72 manufacturing sectors, in 28 countries from 1991 to 2006, we investigated whether there are different patterns of retaliatory antidumping duties (AD) between the developed and developing countries. We find that the four traditional AD heavy users, which are the developed countries, such as Australia, Canada, EU and US, tend to be more sensitive to initiated AD than measured AD of exporting countries, while the five new AD heavy users, which are the developing countries, such as Argentina, Brazil, India, Mexico, South Africa, tend to be more sensitive to measured AD than initiated AD. However, the disproportionate reactions of countries disappear for the period of 1998-2006, which implies an institutional learning from past experience of retaliatory AD. For the whole period, we also find that it disappears only at the country level.

신도시 건설과정에서의 주민갈등 사례연구

허준영(Hur, Joon-Young),문지은(Moon, Jieun) 서울행정학회 2017 한국사회와 행정연구 Vol.27 No.4

행정수도로 지정된 세종신도시는 정부계획에 따라 2012년 이래 과반이상의 부처 및 소속기관, 해당 공무원과 가족들의 이주가 진행되고, 자족도시로서의 기반을 다지며 급격한 성장을 경험하고 있다. 하지만 단기간 집중적으로 도시 건설이 이뤄지면서 대규모 이주·정착 과정에서 이주민과 원주민 집단 간 갈등이 나타나고 있어 갈등의 해결이 도시발전과 사회통합 제고를 위해 긴요한 과제로 부각되고 있다. 본 연구는 대표적인 세종시 주민갈등 사례들(법정동 명칭 변경, 신청사 건립계획, 성남중학교 교명 변경)을 선정하여, 주민통합을 위한 갈등관리적 측면에서 갈등의 구조적·관계적·관리적 특성을 분석하였다. 분석결과 선정된 세 가지 사례는 원주민과 이주민이라는 양분된 두 집단의 갈등을 중심으로 구조화되었고, 갈등관리의 주체인 행정기관의 예방적 갈등기능, 적극적 조정노력이 미흡한 채 갈등은 봉합되어 있는 상태로 머물러 있었다. 또한 신도시 갈등의 주된 속성인 개발에 따른 재산권 변화에 대한 인식과 보상, 이해관계 등이 갈등의 원인이 되기도 했으나, 이주민과 원주민사이의 문화적, 정서적 정체성을 둘러싼 갈등이 도드라지게 나타나고 있음을 확인할 수 있다. 정치·경제적 이해관계를 둘러싼 전형적인 갈등 관리와 대별하여 문화나 정서 등이 이질적인 집단들의 정체성 문제로 인해 발생하는 갈등의 경우 관리와 접근법이 달라질 필요가 있다. The new administrative city, Sejong New Town, which serves as the administrative capital, has been designated as such by the majority of ministries and agencies and their families since 2012. Accordingly, as the new self-sufficient town, it is rapidly expanding. However, as construction of the new town concentrated within a short period of time following the government plan, the conflict between large-scale migrants and residents has emerged as a crucial task to foster conflict resolution and social integration. We selected typical three cases of conflict between migrants and residents in Sejong new town (Change of ‘Beopjeongdong’ name, plan for new city hall construction, change of Sungnam middle school name), analyzed these cases from the perspective on conflict management with structural, relational, and managerial characteristics of conflict. Using case studies, this paper identified the structure of conflict centers around the two groups: migrants and residents, and the administrative agencies, which are responsible for conflict management, lacks preventive role and active coordination efforts, so conflicts remain unsolved. Also, we found aside from conflict about change in property right, interests and compensation, there were greater conflicts on cultural, emotional identities. It is likely that there will be different approaches to conflict management, unlike the conflict involving political or economic interests, the cultural or identity conflicts between disparate groups.

비자발적 이주와 주민갈등 - 문화충격(culture clash) 관점에서의 탐색적 사례연구 -

허준영 ( Joon-young Hur ),문지은 ( Jieun Moon ) 한국정책학회 2017 韓國政策學會報 Vol.26 No.2

본 연구는 세종신도시 건설로 인해 비자발적 동기로 이주하게 된 공무원과 부양가족 등 이주민과 토박이 원주민간의 주민갈등의 쟁점을 살펴보고 원인을 분석하고자 하였다. 양 집단의 상이한 사회문화적 배경으로 말미암아 마치 문화충돌처럼 발생하는 갈등의 기저를 파악해 내기 위해 심층인터뷰와 초점집단인터뷰(FGI)가 활용되었다. 갈등의 쟁점은 정치(대표구성), 경제(예산배분), 사회(지역사업), 문화(상호인식) 등 4가지 영역으로, 각 영역의 쟁점은 Moore의 갈등주기분석모델과 Mayer의 정체성 기반수요 논의를 결합한 분석틀을 이용하여 갈등의 원인을 분석하였다. 연구결과, 의제확산경로의 차이로 인한 사실관계의 왜곡(사실관계 갈등), 예산 등 한정된 자원의 불균형 배분 및 집행(이해관계 갈등), 정부계획의 번복, 힘의 불균형 등으로 인한 불합리한 제도적·구조적 시스템 생성(구조적 갈등), 관계형성의 어려움으로 인한 불신, 오해, 편견의 발생(관계상의 갈등), 문화 등 가치관 차이로 인한 지역공동체 응집력의 차이(가치관 갈등), 사회적인 환경변화에 따른 지역정체성 형성의 차이(정체성 갈등)가 주민 간 갈등의 기저에 자리잡고 있음을 확인하였다. 특히 세종시 주민 간 갈등은 가치관과 정체성 갈등이 도드라지면서 사실관계나 구조 갈등까지 영향을 미치고 있다는 점에서 문화나 정서 등이 이질적인 집단들의 가치관과 정체성 문제로 인한 갈등에 대한 적극적인 접근과 관리의 필요성이 강조될 필요가 있다. The study examined the causes and key issues of conflict between immigration officials and long-lived residents in Sejong New town. Migration begun with involuntary motivations under government policy, it also caused a cultural clash between newcomers and long-term residents with different social and cultural backgrounds. The key issues arising from each area were diagnosed by using the conflict analytic framework, which was combined with Moore`s the circle of conflict model, with Mayer`s identity-based demand. We conducted in-depth interviews and focus group interviews (FGI) between migrants and indigenous people, and then derived from the issues of conflict which were divided into four areas: politics (representative composition), economy (budget allocation), society (local business), and culture (mutual awareness). Based on the key conflicting issues of each of these categories, we attempted to draw up the analytical framework based on Moore`s model and Mayer`s identity-based demand. The results have shown as follows. There was a deep-rooted discrepancy in the agenda diffusion path, resulting in the distortion of the fact relationship (conflict in fact), unbalanced distribution and enforcement of limited resources such as a budget (conflict in interest). Also, there was a reversal of government plans, building an irrational institutional and structural system, due to imbalance of power (conflict in structure), differences in local community cohesion due to differences in cultural values, or identity etc., (conflict in identity) at the base of the conflicts. In particular, the government should actively deal with the conflicts between the residents of Sejong New town, and emphasize the management of conflicts, concerning values and identity issues in heterogeneous groups. These conflicts eventually may effect another factual or structural conflict.

Functional links between clustered microRNAs: suppression of cell-cycle inhibitors by microRNA clusters in gastric cancer

Kim, Young-Kook,Yu, Jieun,Han, Tae Su,Park, Seong-Yeon,Namkoong, Bumjin,Kim, Dong Hyuk,Hur, Keun,Yoo, Moon-Won,Lee, Hyuk-Joon,Yang, Han-Kwang,Kim, V. Narry Oxford University Press 2009 Nucleic acids research Vol.37 No.5

<P>microRNAs (miRNAs) play integral roles in diverse processes including tumorigenesis. miRNA gene loci are often found in close conjunction, and such clustered miRNA genes are transcribed from a common promoter to generate polycistronic primary transcript. The primary transcript (pri-miRNA) is then processed by two RNase III proteins to release the mature miRNAs. Although it has been speculated that the miRNAs in the same cluster may play related biological functions, this has not been experimentally addressed. Here we report that the miRNAs in two clusters (miR-106b∼93 ∼ 25 and miR-222 ∼ 221) suppress the Cip/Kip family members of Cdk inhibitors (p57<SUP>Kip2</SUP>, p21<SUP>Cip1</SUP> and p27<SUP>Kip1</SUP>). We show that miR-25 targets p57 through the 3′-UTR. Furthermore, miR-106b and miR-93 control p21 while miR-222 and miR-221 regulate both p27 and p57. Ectopic expression of these miRNAs results in activation of Cdk2 and facilitation of G1/S phase transition. Consistent with these results, both clusters are abnormally upregulated in gastric cancer tissues compared to the corresponding normal tissues. Ectopic expression of miR-222 cluster enhanced tumor growth in the mouse xenograft model. Our study demonstrates the functional associations between clustered miRNAs and further implicates that effective cancer treatment may require a combinatorial approach to target multiple oncogenic miRNA clusters.</P>

한류 기반 한국어 학습자를 위한 팬픽션 활용 방안 탐색

문진숙 ( Moon Jinsook ),이미정 ( Lee Mijung ),허지은 ( Hur Jieun ) 국제한국어교육학회 2021 한국어 교육 Vol.32 No.1

This study aims to explore the possibility of utilizing fan fiction as an education method to teach K-culture based Korean language. Korean language education using fan fiction is a new attempt to reflect the expectations and demands of Korean Wave-based learners through active participation. In this study, we discuss the specific meaning and educational benefits of fan fiction and searched for ways to utilize it in the Korean language education field. Based on case studies conducted overseas, we observed the educational impact of fan fiction resulting in voluntary language learning and improvements in learners’ language aptitude through active feedback and various communication activities. In order to apply this fan fiction to the Korean language education field, it was important to establish “affinity spaces” along with how and where voluntary and active communication could take place in educational challenges. This study is meaningful in that it explored ways for K-culture based learners to learn Korean actively and efficiently through fan fiction. It also presents educational spaces and measures that meet the needs of the timely requirements, where the importance of online classes is emphasized. (KyungHee University)

Textile Speaker Using Polyvinylidene Fluoride/ZnO Nanopillar on Au Textile for Enhancing the Sound Pressure Level

Park, Siyong,Ahn, Seongcheol,Kim, Jinhoon,Jeong, Jieun,Park, Tae Hyun,Yoon, Hyeonseok,Hur, Jaehyun,Park, Jong-Jin American Scientific Publishers 2018 Science of advanced materials Vol.10 No.12

온도, 배경이온세기, 결정성장시간 변화에 따른 합성 스트론티아나이트(SrCO₃)의 특성 연구

이선용(Seon Yong Lee),이충현(Choong Hyun Lee),허혁(Hyuck Hur),서지은(Jieun Seo),이영재(Young Jae Lee) 한국암석학회 2015 한국암석학회 학술발표회 논문집 Vol.2015 No.5

Detection of cancer cells during gastric cancer surgery

Tae-Su Han,Hye Seong Ahn,Moon-Won Yoo,Keun Hur,Sang-Ho Jeong,JiEun Yu,Hyuk-Joon Lee,V. Narry Kim,Han-Kwang Yang 대한종양외과학회 2009 대한임상종양학회 학술대회지 Vol.2009 No.3