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      • KCI등재

        Modeling and experimental studies of ammonia absorption in a spray tower

        Shichao Ye,Jie Zhu,Zhenhua Liu,Jie Bai,Yunfeng Yang,Qin Peng 한국화학공학회 2016 Korean Journal of Chemical Engineering Vol.33 No.1

        We did an experimental study on ammonia absorption in a spray tower. The kinetic characteristics of droplets were investigated by considering the forces acting on a droplet. The gas-phase mass transfer coefficient was deduced with the Colburn analogy method. A simplified model for predicting NH3 capture with a spray tower has been presented based on mass transfer and ionic equilibrium, which was successfully validated against experimental data. The influences and the sensitivity analysis of main operating parameters on the absorption efficiency were analyzed. As the most sensitive parameter, the mean droplet diameter was obtained by fitting experimental data with an empirical correlation. The distributions of two typical process parameters along the absorber were also simulated. Decreasing the pH value of absorbent is an effective but restrictive way to strengthen the mass transfer rate on account of insufficient liquid-side resistance.

      • Down-regulated MYH11 Expression Correlates with Poor Prognosis in Stage II and III Colorectal Cancer

        Wang, Ren-Jie,Wu, Peng,Cai, Guo-Xiang,Wang, Zhi-Min,Xu, Ye,Peng, Jun-Jie,Sheng, Wei-Qi,Lu, Hong-Fen,Cai, San-Jun Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.17

        The MYH11 gene may be related to cell migration and adhesion, intracellular transport, and signal transduction. However, its relationship with prognosis is still uncertain. The aim of this study was to investigate correlations between MYH11 gene expression and prognosis in 58 patients with stage II and III colorectal cancer. Quantitative real-time polymerase chain reaction was performed in fresh CRC tissues to examine mRNA expression, and immunohistochemistry was performed with paraffin-embedded specimens for protein expression. On univariate analysis, MYH11 expression at both mRNA and protein levels, perineural invasion and lymphovascular invasion were related to disease-free survival (p<0.05; log-rank test). Cancers with lower MYH11 expression were more likely to have a poor prognosis. Otherwise, MYH11 expression was unrelated to patient clinicopathological features. On multivariate analysis, low MYH11 expression proved to be an independent adverse prognosticator (p<0.05). These findings show that MYH11 can contribute to predicting prognosis in stage II and III colorectal cancers.

      • Influence of Ribosomal Protein L39-L in the Drug Resistance Mechanisms of Lacrimal Gland Adenoid Cystic Carcinoma Cells

        Ye, Qing,Ding, Shao-Feng,Wang, Zhi-An,Feng, Jie,Tan, Wen-Bin Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.12

        Background: Cancer constitutes a key pressure on public health regardless of the economy state in different countries. As a kind of highly malignant epithelial tumor, lacrimal gland adenoid cystic carcinoma can occur in any part of the body, such as salivary gland, submandibular gland, trachea, lung, breast, skin and lacrimal gland. Chemotherapy is one of the key treatment techniques, but drug resistance, especially MDR, seriously blunts its effects. As an element of the 60S large ribosomal subunit, the ribosomal protein L39-L gene appears to be documented specifically in the human testis and many human cancer samples of different origins. Materials and Methods: Total RNA of cultured drug-resistant and susceptible lacrimal gland adenoid cystic carcinoma cells was seperated, and real time quantitative RT-PCR were used to reveal transcription differences between amycin resistant and susceptible strains of lacrimal gland adenoid cystic carcinoma cells. Viability assays were used to present the amycin resistance difference in a RPL39-L transfected lacrimal gland adenoid cystic carcinoma cell line as compared to control vector and null-transfected lacrimal gland adenoid cystic carcinoma cell lines. Results: The ribosomal protein L39-L transcription level was 6.5-fold higher in the drug-resistant human lacrimal gland adenoid cystic carcinoma cell line than in the susceptible cell line by quantitative RT-PCR analysis. The ribosomal protein L39-L transfected cells revealed enhanced drug resistance compared to plasmid vector-transfected or null-transfected cells as determined by methyl tritiated thymidine (3H-TdR) incorporation. Conclusions: The ribosomal protein L39-L gene could possibly have influence on the drug resistance mechanism of lacrimal gland adenoid cystic carcinoma cells.

      • SCIESCOPUSKCI등재

        A High-efficiency Trim Method for CFD Numerical Calculation of Helicopter Rotors

        Ye, Zhou,Xu, Guo-hua,Shi, Yong-jie,Xia, Run-ze The Korean Society for Aeronautical and Space Scie 2017 International Journal of Aeronautical and Space Sc Vol.18 No.2

        In order to resolve the trimming difficulty in rotor CFD calculations, a high-efficiency and improved "delta trim method" is established to compute the blade control settings that are necessary to identify the blade motion. In this method, a simplified model which combines the blade element theory and different inflow models is employed to calculate the control settings according to the target aerodynamic forces, then it is coupled into a CFD solver with unsteady Navier-Stokes equations by the delta methodology, which makes the control settings and aerodynamics calculated and updated in the meantime at every trim cycle. Different from the previous work, the current research combines the inflow model based on prescribed wake theory. Using the method established, the control settings and aerodynamic characteristics of Helishape 7A, AH-1G and Caradonna-Tung rotors are calculated. The influence of different inflow models on trimming calculations is analyzed and the computational efficiency of the current "delta trim method" is compared with that of the "CFD-based trim method". Furthermore, for the sake of improving the calculation efficiency, a novel acceleration factor method is introduced to accelerate the trimming process. From the numerical cases, it is demonstrated that the current "delta trim method" has higher computational efficiency than "CFD-based trim method" in both hover and forward flight, and up to 70% of the amount of calculation can be saved by current "delta trim method" which turns out to be satisfactory for engineering applications. In addition, the proposed acceleration factor shows a good ability to accelerate the trim procedure, and the prescribed wake inflow model is always of better stability than other simple inflow models whether the acceleration factor is utilized in trimming calculations.

      • KCI등재

        Serum microRNA-381: A Potential Marker for Early Diagnosis of Gastric Cancer

        Ye Li,Huihui Sun,Jie Guan,Tingting Ji,Xinwei Wang 연세대학교의과대학 2019 Yonsei medical journal Vol.60 No.8

        Purpose: The purpose of this study was to explore the potential early diagnostic value of serum microRNA-381(miRNA-381) inpatients with gastric cancer (GC). Materials and Methods: Patients with advanced gastric cancer (AGC) and early gastric cancer (EGC), as well as healthy individuals,were enrolled in this study. Expression of miRNA-381 in serum was detected using real-time quantitative PCR. Electrochemiluminescenceanalysis was used to investigate the expression of classic tumor markers, including carbohydrate antigen (CA) 199,CA724, and carcinoembryonic antigen. Finally, receiver operating characteristic curve and Kaplan-Meier analysis were used todetermine the value of miRNA-381 in clinical diagnosis of GC. Results: miRNA-381 was differentially expressed among the study groups. AUC analysis showed that the sensitivity and specificityof serum miRNA-381 in the diagnosis of GC were superior to those of other tumor markers. Furthermore, low levels of miRNA-381 expression were positively correlated with lymph node metastasis and AGC. Finally, Kaplan-Meier survival analysisshowed that down-regulation of miRNA-381 was associated with lymph node metastasis and the development of GC. Conclusion: miRNA381, which was down-regulated in GC, might be a novel early diagnosis marker for patients with GC.

      • KCI등재

        Infrared-to-visible upconversion enhanced photothermal catalytic degradation of toluene over Yb3+, Er3+: CeO2/attapulgite nanocomposite: Effect of rare earth doping

        Jie Huang,Xuhua Ye,Wenjun Li,Anqi Shi,Xini Chu,Ziwen Cao,Chao Yao,Xiazhang Li 한국공업화학회 2022 Journal of Industrial and Engineering Chemistry Vol.116 No.-

        Developing low cost and efficient strategy to eliminate volatile organic compounds (VOCs) are quite urgent and challenging. Herein, CeO2 nanoparticles co-doped with Yb3+ and Er3+ were immobilized on attapulgite clay (ATP) for photothermal catalytic oxidation of toluene. The CeO2:Yb3+, Er3+/ATP exhibited outstanding catalytic activity with low T90 of 295 °C (temperature at 90% degradation), satisfactory stability and highly water resistance. The enhanced photothermal catalytic performance can be attributed to the optimal introduction of Yb3+ and Er3+, which promoted the up-conversion of near-infrared light (NIR) to visible light increasing the light utilization. The defects caused by Yb3+/Er3+ doping facilitated the adsorption of O2, while the active oxygen species generated from the defects and the photoinduced reactive species not only favored the oxidation of toluene in photothermal catalytic process, but also accelerated the reoxidation of reduced catalyst. Notably ATP support provided large specific surface area and abundant adsorption sites for toluene molecules to promote the deep oxidation and hindered the deactivation of catalysts caused by the accumulation of intermediates. In-situ DRIFTS test revealed that the alkoxide and benzoate appeared as the main intermediates, which can be deeply oxidized under light irradiation. Current work provides a new alternative for photothermal catalytic degradation of VOCs.

      • SCIESSCISCOPUSKCI등재

        Positive Association of Human SHC3 Gene with Schizophrenia in a Northeast Chinese Han Population

        Ye Lv,Yang Sun,Guan-Yu Wang,Jian Yin,Cheng-Jie Li,Yi-Yang Luo,Zhi-Lin Luan 대한신경정신의학회 2020 PSYCHIATRY INVESTIGATION Vol.17 No.9

        Objective Schizophrenia is one of the most devastating neuropsychiatric disorders. Genetic epidemiological studies have confirmed that schizophrenia is a genetic disease. Genes promoting neurodevelopment may be potential candidates for schizophrenia. As an adaptor linking a number of tyrosine kinase receptors in multiple intracellular signaling cascades, Src homology 2 domain containing transforming protein 3 (SHC3) is a member of the Shc-like adaptor protein family, and expressed predominantly in the mature neurons of the central nervous system (CNS). In the present study, we aimed to investigate the association of SHC3 and schizophrenia. Methods An independent case-control association study was performed in a sample including 710 schizophrenia patients and 1314 healthy controls from a Northeast Chinese Han population. Results The allelic and genotypic association analyses showed that four SNPs in SHC3 significantly associated with schizophrenia(rs2316280, rs4877041, rs944485 and rs7021743). The haplotype composing of these four SNPs also showed significantly individual and global association with schizophrenia. Conclusion Our present results suggest SHC3 as a susceptibility gene for schizophrenia.

      • Nonlinear structural model updating based on the Deep Belief Network

        Ye Mo,Zuo-Cai Wang,Genda Chen,Ya-Jie Ding,Bi Ge 국제구조공학회 2022 Smart Structures and Systems, An International Jou Vol.29 No.5

        In this paper, a nonlinear structural model updating methodology based on the Deep Belief Network (DBN) is proposed. Firstly, the instantaneous parameters of the vibration responses are obtained by the discrete analytical mode decomposition (DAMD) method and the Hilbert transform (HT). The instantaneous parameters are regarded as the independent variables, and the nonlinear model parameters are considered as the dependent variables. Then the DBN is utilized for approximating the nonlinear mapping relationship between them. At last, the instantaneous parameters of the measured vibration responses are fed into the well-trained DBN. Owing to the strong learning and generalization abilities of the DBN, the updated nonlinear model parameters can be directly estimated. Two nonlinear shear-type structure models under two types of excitation and various noise levels are adopted as numerical simulations to validate the effectiveness of the proposed approach. The nonlinear properties of the structure model are simulated via the hysteretic parameters of a Bouc-Wen model and a Giuffré- Menegotto-Pinto model, respectively. Besides, the proposed approach is verified by a three-story shear-type frame with a piezoelectric friction damper (PFD). Simulated and experimental results suggest that the nonlinear model updating approach has high computational efficiency and precision.

      • KCI등재

        An Approximate Calculation Model for Electromagnetic Devices Based on a User-Defined Interpolating Function

        Ye Xuerong,Deng Jie,Wang Yingqi,Zhai Guofu 한국자기학회 2014 Journal of Magnetics Vol.19 No.4

        Optimization design and robust design are significant measures for improving the performance and reliability of electromagnetic devices (EMDs, specifically refer to relays, contactors in this paper). However, the implementation of the above-mentioned design requires substantial calculation; consequently, on the premise of guaranteeing precision, how to improve the calculation speed is a problem that needs to be solved. This paper proposes a new method for establishing an approximate model for the EMD. It builds a relationship between the input and output of the EMD with different coil voltages and air gaps, by using a user-defined interpolating function. The coefficient of the fitting function is determined based on a quantum particle swarm optimization (QPSO) method. The effectiveness of the method proposed in this paper is verified by the electromagnetic force calculation results of an electromagnetic relay with permanent magnet.

      • Damping Controller Design for Triangular Scanning of a Third-Order Nanopositioning Stage

        Jie Ling,Tingting Ye,Zhao Feng,Min Ming,Xiaohui Xiao 제어로봇시스템학회 2019 제어로봇시스템학회 국제학술대회 논문집 Vol.2019 No.10

        In this paper, a design procedure of damping controller for third-order nanopositioning stage is presented for high-speed triangular scanning. Conventionally, damping control schemes of integral resonant control (IRC) and resonance-shifted IRC (RS-IRC) are designed providing that a second-order model can be identified for a nanopositioning stage. For a third-order system, existing control schemes cannot be applied directly. For this, a pole-zero cancellation technique is presented to design IRC scheme. In addition, a state observer based pole placement technique is proposed for RS-IRC design. The effectiveness of the proposed design procedures is demonstrated through both simulations and experiments based on a piezo-actuated nanopositioning stage platform. Results show that a closed-loop bandwidth of 156 Hz and 186 Hz are obtained by designed IRC and RS-IRC for the third-order nanopositioning stage, and the root-mean-square (RMS) errors of 40 Hz triangular tracking are 49 nm and 13 nm under IRC and RS-IRC control, respectively.

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