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RISS 인기검색어
- 검색키워드
- 저자 : Jaehuk Choi (검색결과 2 건)
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Choi, Jaehuk,Heo, Ran,Hong, Geu-Ru,Chang, Hyuk-Jae,Sung, Ji Min,Shin, Sang Hoon,Cho, In Jeong,Shim, Chi-Young,Chung, Namsik American Heart Association, Inc. 2014 Circulation. Cardiovascular imaging Vol.7 No.3
<P><B>Background—</B></P><P>The aim of this study is to explore the differential effect of 3-dimensional color Doppler echocardiography for the quantification of mitral regurgitation (MR). Two-dimensional color Doppler echocardiography–based MR quantification has well-documented limitations.</P><P><B>Methods and Results—</B></P><P>We consecutively enrolled 221 patients with MR. Adequate image quality was obtained by 2D- and 3D-color Doppler echocardiography in 211 (95.5%) patients. The quantitative differences between the MR volumes obtained by 2D- and 3D-proximal isovelocity surface area (PISA) were analyzed in various MR subgroups. In the validation cohort (n=52), MR volume obtained by 3D-PISA showed a better agreement with phase-contrast cardiac MRI than 2D-PISA (<I>r</I>=0.97 versus 0.84). In all 211 patients, 2D-PISA underestimated the MR volume when compared with 3D-PISA (52.4±19.6 versus 59.5±25.6 mL; <I>P</I>=0.005). A total of 33.3% with severe MR based on 3D-PISA were incorrectly assessed by 2D-PISA as having nonsevere MR. In the subgroup analysis, the MR severity (odds ratio, 6.96; 95% confidence interval, 3.04–15.94; <I>P</I><0.001) and having an asymmetrical orifice (odds ratio, 11.48; 95% confidence interval, 3.72–35.4; <I>P</I><0.001), and an eccentric jet (odds ratio, 3.82; 95% confidence interval, 1.27–11.48; <I>P</I>=0.017) were predictors of significant difference in MR volume (>15 mL) between 2D- and 3D-PISA methods.</P><P><B>Conclusions—</B></P><P>Quantification of MR by 3D-PISA method is clinically feasible and more accurate than the current 2D-PISA method. MR quantification by 2D-PISA significantly underestimated MR volume with severe, eccentric MR with an asymmetrical orifice. This article demonstrates that 3D-color Doppler echocardiography could be used as a valuable tool to confirm treatment strategy in patients with significant MR.</P>
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Se-Hun Kim,Hye-Sun Seo,Nae-Hee Lee,Jaehuk Choi,Tae Hoon Ha,Jon Suh,Youn-Haeng Cho 순천향대학교 순천향의학연구소 2011 Journal of Soonchunhyang Medical Science Vol.17 No.2
Objective: Metabolic syndrome (MS) is associated with increased left ventricular (LV) mass and diastolic dysfunction. This study uses relatively load-independent Doppler tissue echocardiography to examine whether MS is associated with decreased longitudinal contractile reserve during dynamic exercise. Methods: A total of 112 patients with relatively well-controlled, treated hypertension who complained of exertional dyspnea were enrolled (average age, 56.7±10.5 years). Fifty-six were non-diabetic patients with MS (group 1), and 56 were age-sex matched hypertensive patients without MS (group 2). Exercise stress echo was performed using a symptom-limited, multistage, supine bicycle exercise test. Multiple Doppler parameters were obtained at baseline, at each stage of exercise. Results: There was no significant difference between the two groups in terms of age, gender, and hemodynamic variables. E/E’, an index of LV filling pressure, was significantly higher in the MS group at rest and during exercise. The longitudinal contractile reserve, the change in S’ (longitudinal tissue velocity) from baseline to peak exercise, was significantly lower in the MS group (2.00±1.65 vs. 2.90±1.66, P=0.015). Multiple regression analysis showed independent association of MS with longitudinal contractile reserve when controlled for confounding factors, such as LV mass index, gender, blood pressure, and age (β=-0.235, P=0.035). Conclusion: Longitudinal contractile reserve was reduced in MS patients compared to others, although both groups demonstrated similar longitudinal contractile function at rest. We present the first demonstration that metabolic syndrome is independently associated with LV systolic dysfunction during exercise in hypertensive patients.
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