Uninary Nicotine and Cotinine Levels in Smokers and Nonsmokers Related to Smoking Habit in Korea

Hwang, Keon-Joong,Rhee, Moon-Soo,Ra, Do-Young The Korean Society of Tobacco Science 2001 한국연초학회지 Vol.23 No.1

This study was conducted to determine the urinary nicotine and cotinine concentration in 126 smokers and 143 nonsmokers. While urine samples were being collected, personal characteristics related to smoking habit such as sex, age, number of years since a person has been a smoker, average number of cigarettes consumed per day, and number of smokers in the family were surveyed. Urinary nicotine and cotinine concentration were analyzed by GC/NPD. The smokers smoked an average 17.0 cigarettes per day and the average concentration of nicotine and cotinine was 3.88 $\mu\textrm{g}$/ml and 3.64 $\mu\textrm{g}$/ml, respectively. The average number of smokers in the family was 0.72 persons and the average concentration of nicotine and cotinine were 0.11 $\mu\textrm{g}$/ml and 0.02 $\mu\textrm{g}$/ml in the urine of non-smokers, respectively. The concentration of nicotine and cotnine in smoker\`s urine was dependent on the number of cigarettes smoked per day(p<0.01). The number of years since a person had been a smoker, and the number of smokers in the family were not associated with the concentration of nicotine and cotinine. Also there was no significant effects of passive smoking on the family of smokers by the level of nicotine and cotinine concentration. We describe the relationship between smoking habit as assessed by urinary nicotine and cotinine excretion. This study provides an evidence for the assessment of active and passive exposure to tobacco smoke.

Statistical approach for development of objective evaluation method on tobacco smoke

Hwang, Keon-Joong,Rhee, Moon-Soo,Ra, Do-Young The Korean Society of Tobacco Science 2000 한국연초학회지 Vol.22 No.2

This study was conducted to develop the objective evaluation method for tobacco smoke. The evaluation was carried out by using the data of cut or blended tobacco components, smoke components, electric nose system (ENS), and sensory test. By using the statistical methods, such as cluster analysis, discriminant analysis, factor analysis, correlation analysis, and multiple regression analysis, the relationship among the data of tobacco, smoke, ENS, and sensory evaluation was studied. By the results of cluster analysis, the data from smoke analysis by GC and ENS were able to select the difference of tobacco leaf characteristics. As the results of discriminant analysis, grouping by the components of tobacco leaves and smoke was possible and the results of GC analysis of smoke could be used for discrimination of tobacco leaves. In the results of factor analysis, nicotine, tar, CO, puff No and pH in the smoke were the factors effecting on the tobacco leaf characteristics. From the correlation analysis, aroma, taste, irritation, and smoke volume of sensory test had high relation to tar, p-cresol threonolatone, levoglucosane, and quinic acid- ${\gamma}$ -lactone of smoke. The ENS data showed high efficiency for discriminant analysis and cluster analysis, but it was not good for factor analysis, and correlation analysis. It was possible to estimate tobacco leaves and their blending characteristics by the analytical data of tobacco leaves, smoke, ENS, and sensory test results. By the multiple regression analysis, some correlation among selected chemical components and sensory evaluation were found. This study strongly indicated that the some chemical analysis data was available for the objective evaluation of tobacco sensory attributes.

Changes of Smoke Components and Smoke Odor by Far Infra-red Radiation in a Closed Room

Hwang, Keon-Joong,Rhee, Moon-Soo,Ra, Do-Young The Korean Society of Tobacco Science 1998 한국연초학회지 Vol.20 No.2

This study was conducted to evaluate the effect of far IR radiation for the elimination of sidestream smoke components in a closed room. The measurements covered particle sizes of 13.8-542.5 nm, particle concentration, TSP, UVPM, FPM, solanesol, and the following gases and vapor components of smoke: carbon dioxide, carbon monoxide, nicotine, and 3-ethenyl-pyridine. Also, the changes of smoke odor strength by far IR radiation were tested by using the electronic nose system. There was no difference between control and far IR radiation in changes of the concentration of $CO_2$ and CO. The concentrations of TSP, UVPM, FPM, solanesol, nicotine, and 3-ethenylpyridine were reduced by far IR radiation. The growth and diminishing rate of RSP diameter was accelerated by far IR radiation compared with control. There was a little difference of smoke odor change with far IR radiation by electronic nose system analysis. Our results indicated that the use of far IR radiation had a little effect on changes of solid, vapor, and odor of smoke, but it had no effect on gaseous components.

Effect of Surfactant on Solvent Extraction for Light Hydrocarbon from Soils

Hwang, Keon-Joong,Atalay, Asmare Korean Society of Environmental Health 1998 한국환경보건학회지 Vol.34 No.1

본 실험은 light hydrocarbon에 오염된 토양을 용매 추출할 때 계면활성제의 영향을 평가하고자 6가지의 계면활성제 (Witbreak DPG-482, Witbreak DRA-22, Witcomul 4016, Witcolate SL-1, Adsee 799, Triton X-100)와 2가지 용매(물, 메타놀)를 대상으로 실험하였다. Light hydrocarbon으로는 benzene, toluene, ethyl bnzene, o-xylene, m-xylene, p-xylene, n-propyl benzene, 1,2,4-trimethyl benzene, 그리고 n-butyl benzene등 9가지를 대상으로 하였다. 계면활성제중 Adsee-799과 Witbreadk DRA-22가 토양중 light hydrocarbon의 물추출 효율을 다소 증가시키는 것으로 나타나고 있으며, 나머지 계면활성제는 효과가 없었다. 또한 물중의 계면활성제의 농도가 0.5%이하에서는 효과가 없는 것으로 나타나고 있으며, 계면활성제의 농도가 4%일때 평균 10.8%의 추출증가 효과가 있었다. 메타놀을 추출용매로 사용할 때에는 Witbread DPG-782와 Witbreak DRA-22가 약 10%의 추출증가 효과를 나타내고 있었다. This study was conducted to evaluate the surfactant solutions which influence solvent extraction from light hydrocarbon contaminated soils. Nine characteristic compounds were studied: benzene, toluene, ethylbenzene, o-xylene, mxylene, p-xylene, n-propylbenzene, 1,2,4-trimethylbenzene, and n-butylbenzene which were found in gasoline. Adsee-799 and Witbreak DRA-22 showed some extractive capacity for light hydrocarbons from soil. There was no added advantage obtained by using other surfactants in this study. No removal of contaminants from soil was observed when the surfactant concentration was 0.5 percent or below. When the surfactant concentration was 4 percent, the average recovery for some hydrocarbons was 10.8 percent, which was the best obtained at these levels. There was 10 percent surfactant contribution for methanol extraction from soil with the Witbreak DPG-482 and Witbreak DRA-22. This study provided a useful screening technique for procedures that can be used to remediate soils contaminated with light hydrocarbons.

Light Hydrocarbon에 오염된 토양의 용매추출조건에 관한 연구

Hwang. Keon-Joong,Atalay. Asmare 한국환경보건학회 1997 한국환경보건학회지 Vol.23 No.4

본 실험은 석유의 주요성분인 benzene, toluene, p,m,o-xylene, ethylbenzene, n-propylbenzene, 1,2,4-trimethylbenzene, n-butylbenzene 등 light hydrocarbon에 오염된 토양의 회복에 필요한 최적 용매추출 조건을 밝히기 위하여 실시하였다. 토양의 수분함량이 증가할수록 추출효율은 감소하였으며, Methanol을 용매로 사용하였을때에 BTEX화합물은 1시간 추출시 최고 추출효율에 도달하였으며 고분자 hydrocarbon은 4시간이상 추출시 최고 추출효율에 도달하였다. 2-Propanol을 추출용매로 사용할때는 모든 light hydrocarbon은 추출 4시간 경과시 최고의 추출효율을 나타냈다. 추출용매와 토양의 비율이 2:1일때 가장 경제적이고 효율적이고 추출이 이루어 졌으며, 0.4mg/g이상의 토양오염 농도에서 최적의 추출효과가 나타났다. 위의 최적조건으로 light hydrocarbon 오염토양을 batch extraction을 이용하여 추출하였을 때 평균 66%의 light hydrocarbon이 회수되었으며, 회수율은 토양의 종류, 추출용매의 종류 그리고 hydrocarbon의 종류에 따라 좌우되었다. 본 연구의 결과는 석유에 오염된 토양의 회복을 위한 토양세척에 사용될 수 있을 것으로 사료된다. This study was conducted to establish an ideal condition for obtaining maximum extraction efficiencies using an array of soil types and under a wide variety of conditions. Nine characteristic compounds were studied: benzene, toluene, ethylbenzene, o-xylene, m-xylene, p-xylene, n-propylbenzene, 1,2,4-trimethylbenzene, and n-butylbenzene which were found in gasoline. Increasing the moisture content resulted in decreased recovery, and recovery of hydrocarbons from wet soils was significantly lower than from dry soils. For the batch extraction process, 4 hours of extraction time was sufficient to give optimum recovery of the contaminants. With methanol as an extraction solvent, maximum recovery time appeared to be reached quicker for BTEX components than with 2-propanol. The 2 to 1 ratio of solvent/soil was chosen as a compromise to provide for the indicated minimum solvent use and high extraction efficiency. The 0.4 mg/g soil contamination was adequate to show quantitative recovery. The percent recovery of BTEX was concentration dependent more than the semivolatile compounds. Methanol and 2-propanol consistently gave higher efficiency than water. Methanol was superior to 2-propanol in removing contaminants from silty clay loam soil. Using the most efficient extraction procedure, the average recovery of the light hydrocarbons from the three soils was 66 percent. Recoveries were also dependent on soil type, solvent type, extraction time, solvent amount, contaminant concentration, and compounds volatility. This study provided a useful screening technique for procedures that can be used to remediate soils contaminated with light hydrocarbons.

토양중 Light Hydrocarbon의 용매추출에 미치는 계면활성제의 영향

Hwang. Keon-Joong,Atalay. Asmare 한국환경보건학회 1998 한국환경보건학회지 Vol.24 No.2

본 실험은 light hydrocarbon에 오염된 토양을 용매 추출할 때 계면활성제의 영향을 평가하고자 6가지의 계면활성제 (Witbreak DPG-482, Witbreak DRA-22, Witcomul 4016, Witcolate SL-1, Adsee 799, Triton X-100)와 2가지 용매(물, 메타놀)를 대상으로 실험하였다. Light hydrocarbon으로는 benzene, toluene, ethyl bnzene, o-xylene, m-xylene, p-xylene, n-propyl benzene, 1,2,4-trimethyl benzene, 그리고 n-butyl benzene등 9가지를 대상으로 하였다. 계면활성제중 Adsee-799과 Witbreadk DRA-22가 토양중 light hydrocarbon의 물추출 효율을 다소 증가시키는 것으로 나타나고 있으며, 나머지 계면활성제는 효과가 없었다. 또한 물중의 계면활성제의 농도가 0.5%이하에서는 효과가 없는 것으로 나타나고 있으며, 계면활성제의 농도가 4%일때 평균 10.8%의 추출증가 효과가 있었다. 메타놀을 추출용매로 사용할 때에는 Witbread DPG-782와 Witbreak DRA-22가 약 10%의 추출증가 효과를 나타내고 있었다. This study was conducted to evaluate the surfactant solutions which influence solvent extraction from light hydrocarbon contaminated soils. Nine characteristic compounds were studied: benzene, toluene, ethylbenzene, o-xylene, mxylene, p-xylene, n-propylbenzene, 1,2,4-trimethylbenzene, and n-butylbenzene which were found in gasoline. Adsee-799 and Witbreak DRA-22 showed some extractive capacity for light hydrocarbons from soil. There was no added advantage obtained by using other surfactants in this study. No removal of contaminants from soil was observed when the surfactant concentration was 0.5 percent or below. When the surfactant concentration was 4 percent, the average recovery for some hydrocarbons was 10.8 percent, which was the best obtained at these levels. There was 10 percent surfactant contribution for methanol extraction from soil with the Witbreak DPG-482 and Witbreak DRA-22. This study provided a useful screening technique for procedures that can be used to remediate soils contaminated with light hydrocarbons.

실내 공기청정기 우형에 따른 ETS 성분 감소 효과

황건중(Keon Joong Hwang),이문수(Moon Soo Rhee),나도영(Do Young Ra) 한국환경보건학회 1999 한국환경보건학회지 Vol.25 No.2

This study was conducted to evaluate the ability of room air cleaners to remove gases, vapor and particles from closed room contaminated with environmental tobacco smoke(ETS). The types of room air cleaners selected were paper filter, fiber filter, carbom filter, static precipitator and anion generater. The ETS measurements covered total suspended particle(TSP), ultraviolet particulate matter(UVPM), fluorescent particulate matter(FPM), solanesol, carbon dioxide, carbon monoxide, nicotine, and 3-ethenylpyridine. Tobacco smoke was generated and mixed in a closed room in which the airflow rates were in the range of 0.00-0.03 m/s. As the room air cleaners were started, the decay rates of the ETS components were measured. After the use of room air cleaners, excluding paper filter cleaner, the solid components of ETS, such as TSP, UVPM, FPM and solanesol were removed over 90%, and the vapor phase components of ETS, such as nicotine, 3-ethenylpyridine(3-EP) were eliminated about 50% as time elapsed. But even after the use of room air cleaners, except the anion generating cleaner, the decreasing rate of carbon dioxide and carbon monoxide concentration were not much different with the control. Our results indicate that there was a different removal efficiency with the types of filter materials in air cleaners, and also there was a dominant effect on reduce of solid and vapor components of ETS. But there was no significant effect on reduce of gaseous components of ETS. It is possible to increase the air quality in a room contaminated by ETS with the conditions that an air cleaner is properly chased, operated and maintained well.

아황산가스가 견조 과정중 잎담배 내용성분에 미치는 영향

황건중(Keon Joong Hwang),석영선(Yeong Seon Seok) 한국환경보건학회 1985 한국환경보건학회지 Vol.11 No.1

This experiment was carried out to study 00 the effect of S02 gas to chemical com_ position of tobacco leaves during flue -curing. The results were as follows : S02 gas io briquet was the major factor to damage with tobacco leaves. The damage ooly occured in a presence of moisture io tobacco leaves, it did oot occured after color fixing stage which is a li ttle leaf moisture. The daoger of damage to tobacco leaves lies in 10 ppm of S02 gas concentration. Follow with the S02 gas concentration increased, sugar and nitrogen ∞ntents became higher, po1yphenol contents were 105s, and the quality of tobacco leaves declin.

환경 중 담배연기(ETS) 성분 분석

황건중,Hwang, Keon Joong 한국연초학회 2013 한국연초학회지 Vol.35 No.1

주류연

황건중,Hwang, Keon-Joong 한국연초학회 2008 한국연초학회지 Vol.30 No.1