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Helix Nucleation via Hydrocarbon Cross-link Mimicking N-capping Box
Luong Thuy Nguyen,Huy Xuan Luong,김영우 대한화학회 2016 Bulletin of the Korean Chemical Society Vol.37 No.4
The N-capping box is a well-known helix-stabilizing motif with a distinct reciprocal backbone–side chain hydrogen-bonding arrangement at the N-terminus of helices. This unique N-terminal flanking motif consists of a hydrogen-bonded cycle of four amino acid residues in which the backbone amide of the N3 residue forms a hydrogen bond with the side chain of the Ncap residue, and reciprocally, the side chain of the N3 accepts a hydrogen from the Ncap amide. In this study, as a new helix-stabilizing strategy, we examined a metathesis-based cross-linking system that mimics the hydrogen bond between the Ncap amide and the side chain of the N3 at the N-terminus. Using this new system, we prepared two alanine/lysine-based model peptides and analyzed its impact on helix stabilization. We found that a 16-membered macrocycle incorporated by ring-closing metathesis effectively induces and stabilizes helical conformations of the given model sequence.
A Concurrent Triple-band RF Energy Harvesting Circuit for IoT Sensor Networks
Luong Duy Manh,Phan Thi Bich,Nguyen Thuy Linh,Nguyen Huy Hoang,Tran Xuan Nam,Koichiro Ishibashi 대한전자공학회 2021 IEIE Transactions on Smart Processing & Computing Vol.10 No.2
In this paper, a concurrent triple-band RF energy harvesting circuit is proposed. The proposed circuit incorporates a triple-band microstrip antenna combining a low-loss diplexer and three compact RF rectifiers. The proposed circuit operates concurrently at three popular frequency bands: GSM-900, GSM-1800, and 2.45 GHz. To improve output voltage and efficiency, three rectifiers are connected in a stacked topology. The simulated and measured results demonstrate that the circuit operates well in concurrent bands. Moreover, the proposed circuit exhibits a low-complexity structure and compactness in size. These advantages make the circuit a strong potential candidate for running low-power devices in IoT sensor networks.
Lan, Truong Thi Phuong,Huy, Nguyen Duc,Luong, Nguyen Ngoc,Quang, Hoang Tan,Tan, Trinh Huu,Thu, Le Thi Anh,Huy, Nguyen Xuan,Loc, Nguyen Hoang The Korean Society of Plant Biotechnology 2019 식물생명공학회지 Vol.46 No.3
The aim of this study is to evaluate the effect of yeast extract (YE) and salicylic acid (SA) on the expression of curcuminoid-biosynthesis genes (CzDCS and CURS1-3), and accumulation of curcumin in Curcuma zedoaria cell cultures. The results showed that, in cells treated with YE or SA, the expression levels of curcuminoid genes were 1.14- to 3.64-fold higher than the control (untreated cells), in which the YE exhibited a stronger effect in comparison with SA. Curcumin accumulation also tended to be similar to gene expression, curcumin contents in YE- or SA-treated cells were 1.61- to 2.53-fold higher than the control. The SA treatment at the fifth day of culture stimulated the curcumin accumulation and expression in all four genes compared to that at the beginning. While the YE treatments gave different results, the CzCURS1 and CzCURS3 genes were expressed strongly in cells that were treated at the beginning. However, the CzDCS and CzCURS2 genes showed the opposite expression pattern, they were activated strongly in the treatments at day five of the culture. However, the content of curcumin reached its maximum value on the fifth day of culture in all investigations.
Nguyen Hoang Loc,Truong Thi Phuong Lan,Nguyen Duc Huy,Nguyen Ngoc Luong,Hoang Tan Quang,Trinh Huu Tan,Le Thi Anh Thu,Nguyen Xuan Huy 한국식물생명공학회 2019 JOURNAL OF PLANT BIOTECHNOLOGY Vol.46 No.3
The aim of this study is to evaluate the effect of yeast extract (YE) and salicylic acid (SA) on the expression of curcuminoid-biosynthesis genes (CzDCS and CURS1-3), and accumulation of curcumin in Curcuma zedoaria cell cultures. The results showed that, in cells treated with YE or SA, the expression levels of curcuminoid genes were 1.14- to 3.64-fold higher than the control (untreated cells), in which the YE exhibited a stronger effect in comparison with SA. Curcumin accumulation also tended to be similar to gene expression, curcumin contents in YE- or SA-treated cells were 1.61- to 2.53-fold higher than the control. The SA treatment at the fifth day of culture stimulated the curcumin accumulation and expression in all four genes compared to that at the beginning. While the YE treatments gave different results, the CzCURS1 and CzCURS3 genes were expressed strongly in cells that were treated at the beginning. However, the CzDCS and CzCURS2 genes showed the opposite expression pattern, they were activated strongly in the treatments at day five of the culture. However, the content of curcumin reached its maximum value on the fifth day of culture in all investigations.