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      • Fatigue Analysis of Lower Limb Muscle Group Using Elliptical Machine with Constant Loading

        ( Li-cheng Hsieh ),( Ching-chia Hsieh ) 한국농업기계학회 2018 한국농업기계학회 학술발표논문집 Vol.23 No.1

        The elliptical machine or trainer is one of the most popular sports equipment for cardiorespiratory fitness training. In recent years, it is widely used in the family and the gymnasium in Taiwan. Therefore, it is necessary for further discussion about the movements of the elliptical machine, and various levels of the lower-limb muscular fatigue using the elliptical machine in various strengths. The research collected the electromyography (EMG) signal of lower limb muscles, and used the commercially available software to analyze the possible timing that the fatigue appeared. The research applied this system to analyze the lower-limb muscular fatigue when using the elliptical machine with a constant resistance. It compiled the relevant literature, developed the experimental methods and analyzed the results. The subjects of this research arranged ten young people who used elliptical trainer for the first time. They carried the EMG and pedaled in a nature way. Then, Fourier transform was applied for all collected data, and the median frequency was calculated from 80% of the maximum value of the mild fatigue. The result showed that 60% of subject’s rectus muscle had been fatigued first. As a result, when using the elliptical trainer, it was much easier to use the muscles of the front thigh and get tired. Most of the fatigue occurred from overusing the lower limb muscle. By understanding the biomechanics of the elliptical trainer, it could avoid or reduce the fatigue and injuries during exercise. The system can analyze the fatigue timing as well. The fatigue analysis results would help the elliptical machine users avoid injuries, and increasing the efficiency of elliptical training.

      • SCIESCOPUSKCI등재

        Longevity, tumor, and physical vitality in rats consuming ginsenoside Rg1

        Chao-Chieh Hsieh,Chiung-Yun Chang,Tania Xu Yar Lee,Jinfu Wu,Suchada Saovieng,Yu-Wen Hsieh,Maijian Zhu,Chih-Yang Huang,Chia-Hua Kuo The Korean Society of Ginseng 2023 Journal of Ginseng Research Vol.47 No.2

        Background: Effects of the major ginsenoside Rg1 on mammalian longevity and physical vitality are rarely reported. Purpose: To examine longevity, tumor, and spontaneous locomotor activity in rats consuming Rg1. Methods: A total of 138 Wistar rats were randomized into 2 groups: control (N = 69) and Rg1 (N = 69). Rg1 (0.1 mg/kg per day) were orally supplemented from 6 months of age until natural death. Spontaneous mobility was measured by video-tracking together with body composition (dual energy x-ray absorptiometry) and inflammation markers at 5, 14, 21, and 28 months of age. Results: No significant differences in longevity (control: 706 days; Rg1: 651 days, p = 0.77) and tumor incidence (control: 19%; Rg1: 12%, p = 0.24) were observed between the two groups. Movement distance in the control group declined significantly by ~60% at 21 months of age, together with decreased TNF-α (p = 0.01) and increased IL-10 (p = 0.02). However, the movement distance in the Rg1 group was maintained ~50% above the control groups (p = 0.01) at 21 months of age with greater magnitudes of TNF-α decreases and IL-10 increases. Glucose, insulin, and body composition (bone, muscle and fat percentages) were similar for both groups during the entire observation period. Conclusion: The results of the study suggest a delay age-dependent decline in physical vitality during late life by lifelong Rg1 consumption. This improvement is associated with inflammatory modulation. Significant effects of Rg1 on longevity and tumorigenesis were not observed.

      • KCI등재

        Effect of Vacuum Brazing on Corrosion Resistance of SAF 2205 and Superdex 64 Duplex Stainless Steel

        Hsieh, Wen-Chin,Chiu, Liu-Ho,Ling, Yi-Chun 한국부식방식학회 2002 Corrosion Science and Technology Vol.31 No.2

        Duplex stainless steel has a combination of better mechanical strength and pitting corrosion resistance, but the precipitated brittle phase as б phase formed during the cooling from the welding procedure will rapidly degrade its properties. In order to avoid the precipitation of secondary phases in the welds, the effect of vacuum brazing on the properties of the welds of UNS S31803 (SAF 2205) and UNS S31200 (SuperDux64) duplex stainless steels has been investigated. Three fillers, such as copper foil, BNi-3 and BNi-7 Ni-based alloy, were used to evaluate the influence of chemical composition on the corrosion resistance. In air quench, a cooling rate of 0.85℃/s and the precipitation of б phase can be inhibited for those studied duplex stainless steels. Under the quenched state, the weight loss of UNS S31803 DSS dipped in 6%FeCl₃ solution at 45℃ for 24 hours is low. However, the precipitation of a phase in UNS S31803 was increased as the cooling rate decreased. When the cooling rate was decreased to 0.067℃/s, the weight loss of UNS S31803 was increased. Owing to the compositional difference between the filler and duplex stainless steel, the selective corrosion occurred at the interface of brazed joints soaked in 6% FeCl₃ solution for 24 hours.

      • SCIESCOPUSKCI등재

        The Relative Centrifugation Force Permits Visualization of the Germinal Vesicle in Pig Oocytes

        Hsieh, Chang-Hsing,Lee, Stone,Jaw, Si-Ning,Tseng, Jung-Kai,Tang, Pin-Chi,Chang, Lan-Hwa,Ju, Jyh-Cherng Asian Australasian Association of Animal Productio 2004 Animal Bioscience Vol.17 No.9

        Pig oocytes contain high levels of lipids in the ooplasm, which reduces the visibility of the germinal vesicle (GV) under microscopic examination. Therefore, the purposes of this study were to investigate the effects of relative centrifugation force (RCF) on the visibility and maturation rates of the GV stage oocytes after centrifugation. In Experiment 1, cumulus-oocyte-complexes (COCs) were collected from slaughterhouse ovaries and randomly allocated to different RCFs (3,000 rpm: 970 g; 6,000 rpm: 3,900 g; or 10,000 rpm: 10,840 g) for 10 or 20 min. Percentages of visible GV were 76-79% in the oocytes centrifuged with 10,000 rpm, which were significantly higher (p<0.01) than those with 3,000 and 6,000 rpm. No significant differences in GV visibility were observed among oocytes with different lengths of centrifugation (p<0.05) regardless of the RCFs. In esperiment 2, the maturation rate of the oocyte was found significantly lower in the 20 min than in the 10 min group received 10,840 g of RCF (30 vs. 75%, p<0.05). In conclusion, the GV of porcine oocytes can be clearly visible by centrifugation at 10,840 g for 10 min without compromising their subsequent maturation rates and a longer centrifugation time (20 min) had no beneficial influence on the visibility of GV stage pig oocytes.

      • Tumors Involving Skin, Soft Tissue and Skeletal Muscle: Benign, Primary Malignant or Metastatic?

        Hsieh, Chi-Ying,Tsai, Huang-Wen,Chang, Chih-Chun,Lin, Tsuo-Wu,Chang, Ke-Chung,Chen, Yo-Shen Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.15

        Background: Metastatic cancer with invasion of skin, soft tissue and skeletal muscle is not common. Examples presenting as soft tissue masses could sometimes lead to misdiagnosis with delayed or inappropriate management. The purpose of current study was to investigate clinical characteristics in the involvement of metastatic cancer. Materials and Methods: A total of 1,097 patients complaining of skin or soft tissue masses and/or lesions were retrospectively reviewed from January 2012 to June 2013. Tumors involving skin, soft tissue and skeletal muscle of head and neck, chest wall, abdominal wall, pelvic region, back, upper and lower extremities were included in the study. Results: Fifty-seven (5.2%) patients were recognized as having malignancies on histopathological examination. The most common involvement of malignancy was basal cell carcinoma, followed by cutaneous squamous cell carcinoma, sarcoma and melanoma. The most common anatomical location in skin and soft tissue malignancies was head and neck (52.6% of the malignancies). Four (0.36%) of the malignant group were identified as metastatic cancer with the primary cancer source from lung, liver and tonsil and the most common site was upper extremities. One of them unexpectedly expired during the operation of metastatic tumor excision at the scalp. Conclusions: Discrimination between benign and malignant soft tissue tumors is crucial. Performance of imaging study could assist in the differential diagnosis and the pre-operative risk evaluation of metastatic tumors involving skin, soft tissue and skeletal muscle.

      • KCI등재

        THE ORBITAL EPHEMERIS OF THE PARTIAL ECLIPSING X-ray BINARY X1822-371

        HSIEH, HUNG-EN,CHOU, YI,HU, CHIN-PING,YANG, TING-CHANG,SU, YI-HAO,LIN, CHING-PING,CHUANG, PO-SHENG,LIAO, NAI-HUI The Korean Astronomical Society 2015 天文學論叢 Vol.30 No.2

        X1822-371 is a low mass X-ray binary with an accretion disk corona exhibiting partial eclipses and pulsations in the X-ray band. We update its orbital ephemeris by combining new RXTE observations and historical records, with a total time span of 34 years. There were 11 RXTE observations in 2011 but the eclipsing profile can be seen in only 4 of them. The eclipsing center times were obtained by fitting the profile with the same model as previous studies. Combined with the eclipsing center times reported by Iaria et al. (2011), the O-C analysis was processed. A quadratic model was applied to fit the O-C results and produced a mean orbital period derivative of $\dot{P}_{orb}=1.339(25){\times}10^{-10}s/s$, which is slightly smaller than previous records. In addition to the orbital modulation from the orbital profile, we also present our preliminary results for measuring the orbital parameters using the orbital Doppler effect from the pulsation of the neutron star in X1822-371. The updated orbital parameters from eclipsing profiles will be further compared with the ones from pulsar timing.

      • KCI등재

        Market States and Lottery Preference: Evidence from Chinese Open-End Funds

        Hsieh Pei‐Lin,He Rongxin 한국증권학회 2023 Asia-Pacific Journal of Financial Studies Vol.52 No.5

        Recent studies find that investors prefer funds with lottery‐like payoffs. Using a sample of Chinese open‐end funds, we show that investors' preference for funds' extreme positive payoffs (MAXs) depend on the state of the market: it is significant for MAXs in an unfavorable market but weak or reversed for those in a favorable market. Such state‐dependent preference is irrational because, inconsistent with the flow–MAX relationship, higher MAXs under market downturns are associated with worse performance. We further document support for the salience‐theory‐based explanation for investors' preference and provide counter‐evidence for alternative mechanisms based on rational choice or changes in aggregate flows.

      • Delivery the Chemotherapeutic Drug through Redox Sensitive Polymeric Nano-carrier for Cancer Treatment

        Hsieh-Chih Tsai 한국고분자학회 2021 한국고분자학회 학술대회 연구논문 초록집 Vol.46 No.2

        Smart drug delivery systems have showed great potential for the disease treatment that can be stimulated by the changes in the environmental parameter. Among all the smart carrier, biocompatible amphiphilic block copolymers have been considered as the most promising bio-materials to delivery of anticancer drug due to the formation core-shell nanoparticles protect the above agents. The self-assembled nanostructure exhibited several advantage when delivery the therapeutic drug, such as improve the solubility and stability of drug before transportation to targeting organs. However, the non-select drug release from the amphiphilic copolymer limit their application in the treatment of cancer disease. Thus, the introducing of stimuli sensitive and easily cleavable groups in the polymer chain during the synthesis of materials is essential to achieve rapid and relatively completely drug release from the carrier in the cancer environment. Therefore, we have synthesized two kind of Di-selenide contained copolymer system (Bi(mPEG-SeSe)-b-(PCL) and Bi(mPEG-b-PLGA)-Se2) and evaluation their drug released mechanism of above two approach. Di-selenide containing block copolymer exhibited the selective drug release only in cancer cells, which can be utilized as targeting strategy for delivery anticancer drug.

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