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Optimization on Ready-Mixed Concrete Dispatching Problem via Sliding Time Window Searching
Machine Hsie,Chun Yen Huang,Wen-Ta Hsiao,Ming-Yen Wu,YuanChi Liu 대한토목학회 2022 KSCE JOURNAL OF CIVIL ENGINEERING Vol.26 No.8
The dispatching of ready-mixed concrete (RMC) is usually scheduled manually and difficult tomeet the demand of construction sites. The inefficient dispatching plan causes concretedefects of discontinuous casting (cold joint formation) or long on-site queuing (concrete earlyhardening inside RMC truck). The RMC dispatching literature focus on optimizing thedispatching intervals to minimize RMC truck on-site queuing, system operation costs of RMCplant and construction sites, or tradeoff. The previous research methods include mixed-integerlinear programming (MILP) and evolutionary algorithms. They have the limitations of providingoptimal solutions or computation efficiency. This paper develops a Binary Linear programmingwith Sliding Time-Window (BLSTW) to overcome these limitations. The BLSTW model subtlydetermines the dispatch of RMC trucks through binary variables incorporated into sliding timewindow search approach. Two perspectives, from the RMC plant supplier and constructionsite demanders, are discussed respectively. Three case studies are conducted to verify theefficiency improvement of the developed model including one largescale example of 25 sites. The comparisons made with two cited results shows the superior of the developed model.
Chien-Ming Wu,Hsiao-Chun Lin,Fang-Yi Cheng,Mu-Hua Chien 한국기상학회 2019 Asia-Pacific Journal of Atmospheric Sciences Vol.55 No.4
In this study, we aim to evaluate the impact of fast land-atmosphere interactions on the afternoon thunderstorm in Taiwan through high-resolution meteorological simulations. For this purpose, the Noah land surface model (LSM) is implemented into the vector vorticity equation cloud-resolving model (VVM) with corresponding realistic land surface data of Taiwan into the coupling system, called TaiwanVVM. Two idealized experiments are conducted by giving the same surface forcing but one with direct land-atmosphere coupling from Noah LSM (called Coupled experiment) and the other with prescribed surface fluxes (called Prescribed experiment). Our results show that the fast land-atmosphere interaction over complex topography has a significant influence on rainfall intensity, especially in the heavy precipitating region where the interaction is strong.Without direct coupling between the land surface and the atmosphere in the Prescribed experiment, the diurnal intensity is suppressed by 50%over whole Taiwan and 70% for East Taiwan. Our findings demonstrate that the intensity of the afternoon thunderstorm is sensitive to fast land-atmosphere interactions by modifying local circulation in the mountainous region of Taiwan.
Chung-Ze Wu,Dee Pei,An-Tsz Hsieh,Kun Wang,Jiunn-Diann Lin,Li-Hsiu Lee,Yi-Min Chu,Fone-Ching Hsiao,Chun Pei,Te-Lin Hsia 대한약학회 2010 Archives of Pharmacal Research Vol.33 No.3
The traditional sulfonylureas with long half-lives have sustained stimulatory effects on insulin secretion compared to the short-acting insulin secretagogue. In this study, we used the frequently sampled intravenous glucose tolerance test (FSIGT) to evaluate the insulin sensitivity (IS), glucose sensitivity (SG), and acute insulin response after glucose load (AIRg) after 4months treatment with either gliclazide or repaglinide. The design of study was randomizedcrossover. We enrolled 20 patients with new-onset type 2 diabetes (mean age, 49.3 years). Totally three FSIGTs were performed, one before and one after each of the two treatment periods as aforementioned. No significant differences in fasting plasma glucose, insulin, body mass index, blood pressure, glycated hemoglobin, or lipids were noted between the two treatments. After the repaglinide treatment, higher AIRg, lower IS, and lower SG were noted, but they did not reach statistical significance. The disposal index (DI) was also not significantly different between the two treatments. In conclusion, since non-significantly higher DI, AIRg, lower IS and SG were noted after repaglinide treatment, it might be a better treatment for diabetes, relative to gliclazide.
Indirect Adaptive Nonlinear Self-Balancing and Station Keeping for Omnidirectional Riding Chair
Ching-Chih Tsai,Yi-Ping Ciou,Feng-Chun Tai,Hsiao-Lang Wu 제어로봇시스템학회 2014 제어로봇시스템학회 국제학술대회 논문집 Vol.2014 No.10
This paper presents indirect adaptive self-balancing and station keeping control methods using recurrent Wavelet Fuzzy CMAC (RWFCMAC) for an omnidirectional ball-driven chair in presence of significant system uncertainties. By backstepping, sliding-mode control and RWFCMAC, the self-balancing controller is synthesized to follow the rider’s inclination angles in both two axes (x-z and y-z axis), and the station-keeping controller is designed to allow the rider to maintain the vehicle at the same place. The RWFCMAC is designed to online learning the uncertainties caused by riders’ weights and different unknown frictions between the ball and terrain surfaces. The superior performance and merit of the proposed control methods are well exemplified by comparing to two existing controllers.
Novel tailoring algorithm for abrupt motion artifact removal in photoplethysmogram signals
Limeng Pu,Pedro J. Chacon,Hsiao-Chun Wu,최진우 대한의용생체공학회 2017 Biomedical Engineering Letters (BMEL) Vol.7 No.4
Photoplethysmogram (PPG) signals are widelyused for wearable electronic devices nowadays. The PPGsignal is extremely sensitive to the motion artifacts (MAs)caused by the subject’s movement. The detection andremoval of such MAs remains a difficult problem. Due tothe complicated MA signal waveforms, none of the existingtechniques can lead to satisfactory results. In this paper,a new framework to identify and tailor the abrupt MAs inPPG is proposed, which consists of feature extraction,change-point detection, and MA removal. In order toachieve the optimal performance, a data-dependent framesizedetermination mechanism is employed. Experimentsfor the heart-beat-rate-measurement application have beenconducted to demonstrate the effectiveness of our proposedmethod, by a correct detection rate of MAs at 98% and theaverage heart-beat-rate tracking accuracy above 97%. Onthe other hand, this new framework maintains the originalsignal temporal structure unlike the spectrum-basedapproach, and it can be further applied for the calculationof blood oxygen level (SpO2).
Wang Hui-Ching,Moi Sin-Hua,Chan Leong-Perng,Wu Chun-Chieh,Du Jeng-Shiun,Liu Pei-Lin,Chou Meng-Chun,Wu Che-Wei,Huang Chih-Jen,Hsiao Hui-Hua,Pan Mei-Ren,Chen Li-Tzong 생화학분자생물학회 2023 Experimental and molecular medicine Vol.55 No.-
Personalized genetic profiling has focused on improving treatment efficacy and predicting risk stratification by identifying mutated genes and selecting targeted agents according to genetic testing. Therefore, we evaluated the role of genetic profiling and tumor mutation burden (TMB) using next-generation sequencing in patients with head and neck squamous cell carcinoma (HNSC). The relapse mutation signature (RMS) and chromatin remodeling mutation signature (CRMS) were explored to predict the risk of relapse in patients with HNSC treated with concurrent chemoradiotherapy (CCRT) with platinum-based chemotherapy. Patients in the high RMS and CRMS groups showed significantly shorter relapse-free survival than those in the low RMS and CRMS groups, respectively (p < 0.001 and p = 0.006). Multivariate Cox regression analysis showed that extranodal extension, CCRT response, and three somatic mutation profiles (TMB, RMS, and CRMS) were independent risk predictors for HNSC relapse. The predictive nomogram showed satisfactory performance in predicting relapse-free survival in patients with HNSC treated with CCRT.