http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
Vancomycin-related Linear IgA Bullous Dermatosis in a Patient with Cervical Cancer
Lee, Mi Suk,Lee, Byeongmahn,Kim, Dong In,Cho, Kun-Hyung,Cha, Heejeong,Suh, Hoseok 대한감염학회 2005 감염과 화학요법 Vol.37 No.1
선상 IgA 수포성 피부병(linear IgA bullous dermatosis; LABD)은 기저막대 항원에 대한 IgA 자가항체에 의해 발생하는 질환이다. IgA 자가항체의 생성 기전은 아직 명확하지 않으며 발생 원인에 따라 특발성과 약제 유발성으로 나누며 자가면역 질환, 악성 종양과 연관되어 나타나기도 한다. 저자들은 내원 1년 전 자궁경부암으로 치료받은 후 추적 관찰 중 요추부위 골수염이 의심되어 입원한 48세 여자에서 vancomycin 사용과 관련되어 발생한 LABD 1예를 보고하는 바다. 환자는 척수 골수염의 치료를 위해 vancomycin을 5일째 투여받던 중갑자기 체간부에서 긴장성 수포가 발생하였으며 피부 조직의 직접 면역 형광검사에서 기저막대 층에 선상의 IgA 침착이 있어 LABD로 진단되었다. 본 증례에서 원인 약제인 vancomycin 중단과 스테로이드, dapsone의 병합 사용 후에도 수포 발생이 계속 지속되었는데 기저 질환인 자궁 경부암의 재발 및 인근 척추 전이가 뒤늦게 발견되어 LABD의 유발에 약제뿐만 아니라 자궁 경부암에 의한 종양연관 피부병이 함께 관여한 것으로 사료된다. LABD is an autoimmune subepidermal bullous disease which is characterized by linear deposition of immunoglobulin (Ig) in the basement membrane. The definite pathogenesis of LABD is still unknown. Some cases of LABD have been associated with drugs. Vancomycin is the most commonly implicated drug. Although LABD is a relatively rare adverse reaction of vancomycin, it is important for clinicians to be aware of this reaction because the use of vancomycin is increasing along with the increase in the incidence of MRSA infections.
Hippocampal neural correlates for values of experienced events.
Lee, Hyunjung,Ghim, Jeong-Wook,Kim, Hoseok,Lee, Daeyeol,Jung, MinWhan The Society 2012 The Journal of neuroscience Vol.32 No.43
<P>Newly experienced events are often remembered together with how rewarding the experiences are personally. Although the hippocampus is a candidate structure where subjective values are integrated with other elements of episodic memory, it is uncertain whether and how the hippocampus processes value-related information. We examined how activity of dorsal CA1 and dorsal subicular neurons in rats performing a dynamic foraging task was related to reward values that were estimated using a reinforcement learning model. CA1 neurons carried significant signals related to action values before the animal revealed its choice behaviorally, indicating that the information on the expected values of potential choice outcomes was available in CA1. Moreover, after the outcome of the animal's goal choice was revealed, CA1 neurons carried robust signals for the value of chosen action and they temporally overlapped with the signals related to the animal's goal choice and its outcome, indicating that all the signals necessary to evaluate the outcome of an experienced event converged in CA1. On the other hand, value-related signals were substantially weaker in the subiculum. These results suggest a major role of CA1 in adding values to experienced events during episodic memory encoding. Given that CA1 neuronal activity is modulated by diverse attributes of an experienced event, CA1 might be a place where all the elements of episodic memory are integrated.</P>
Lee, Minho,Heo, Eunyoung,Lim, Heesook,Lee, Jun Young,Weon, Sangho,Chae, Hoseok,Hwang, Hee,Yoo, Sooyoung Korean Society of Medical Informatics 2015 Healthcare Informatics Research Vol.21 No.1
<P><B>Objectives</B></P><P>We aimed to develop a common health information exchange (HIE) platform that can provide integrated services for implementing the HIE infrastructure in addition to guidelines for participating in an HIE network in South Korea.</P><P><B>Methods</B></P><P>By exploiting the Health Level 7 (HL7) Clinical Document Architecture (CDA) and Integrating the Healthcare Enterprise (IHE) Cross-enterprise Document Sharing-b (XDS.b) profile, we defined the architectural model, exchanging data items and their standardization, messaging standards, and privacy and security guidelines, for a secure, nationwide, interoperable HIE. We then developed a service-oriented common HIE platform to minimize the effort and difficulty of fulfilling the standard requirements for participating in the HIE network. The common platform supports open application program interfaces (APIs) for implementing a document registry, a document repository, a document consumer, and a master patient index. It could also be used for testing environments for the implementation of standard requirements.</P><P><B>Results</B></P><P>As the initial phase of implementing a nationwide HIE network in South Korea, we built a regional network for workers' compensation (WC) hospitals and their collaborating clinics to share referral and care record summaries to ensure the continuity of care for industrially injured workers, using the common HIE platform and verifying the feasibility of our technologies.</P><P><B>Conclusions</B></P><P>We expect to expand the HIE network on a national scale with rapid support for implementing HL7 and IHE standards in South Korea.</P>
임상 의사결정 지원 서비스 기반 u-health 포털 시스템 참조 모델
채호석(HoSeok Chae),김정아(JeongAh Kim),최민희(MinHee Choi),오성영(SungYoung Oh),이민호(MinHo Lee),이치우(ChiWoo Lee) 한국정보기술학회 2011 한국정보기술학회논문지 Vol.9 No.7
The specialization and diversity of medial service and the development of device is evolving from face-to face medical system to new types of medical services such as prevention, after-care service, and the medical service based on patients’ needs. The importance of CDS(Clinical Decision Support) Service is also increasing in u-health since CDS service provides patient-specific suggestions with medical evidences. In this paper, we suggested reference model for u-health portal system based on CDS service. Service model, process model and system architecture are included in suggested reference model. Also, glycosuria u-health system was developed based on proposed reference model to provide the case study and to check the feasibility of reference model.