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Kwak Kyu‐Won,Aktaruzzaman Md.,Kim Eunsun,Kim Sun Young,Hong Seung‐Beom,Park Ji Yeong,Park Kwanho,Koo Bonwoo,Kim Yong‐Soon 한국곤충학회 2021 Entomological Research Vol.51 No.12
Edible insects are considered novel protein sources, and the edible insect breeding industry is growing rapidly. However, fungal pathogens are a major threat to this industry, and appropriate identification of causative agents is important for the development of antifungal agents. In 2019, strains of the fungal pathogen Metarhizium were isolated from infected second and third instar larvae of the economically important edible insect Protaetia brevitarsis, which were collected from separate farms in Gimhae-si, Gyeongsangnam-do, Korea. Based on morphological characteristics and multilocus phylogenetic analysis of the internal transcribed spacer region, and 50-region of gene encoding the 1-α elongation factor, the fungal strains were identified as Metarhizium majus. Here, we report the detailed phylogenetic characteristics and morphological description of this species, which is prevalent in Korea. Identification of the principal disease-causing agent can help develop disease prevention and antifungal strategies for application in edible insect-rearing farms.
갑상선의 호산구증 경화 점액표피양 암종: 원격전이를 동반한 증례보고
김주흥,김석모,홍순원1,장항석,박정수,Joo Heung Kim,Seok-Mo Kim,Soon Won Hong1,Hang-Seok Chang,Cheong Soo Park 대한갑상선-내분비외과학회 2014 The Koreran journal of Endocrine Surgery Vol.14 No.4
Sclerosing mucoepidermoid carcinoma with eosinophilia (SMECE) of the thyroid gland is a very rare carcinoma. We herein report on a case of SMECE with metastasis to bilateral lateral neck nodes, esophagus, and trachea. A 72-year-old woman presented with a neck mass found incidentally during a medical check-up. She had a history of cerebral stroke without sequelae 20 years ago and was taking aspirin regularly. The neck mass was confirmed as papillary thyroid carcinoma by fine needle aspiration biopsy. The patient underwent bilateral total thyroidectomy with central compartment and bilateral compartment lateral neck dissection. The right recurrent laryngeal nerve was sacrificed due to tumor invasion. The trachea wall and esophagus were also invaded by the cancer. Histologically, the tumor showed dense fibrohyaline stroma and a goblet cell, nested islands of squamoid cells, and marked stromal eosinophilia with perineural invasion and lymphovascular invasion, confirming the diagnosis of SMECE. After radiation therapy for three months, distant metastasis to the liver, lung, and bone were found on PET-CT. This case appears to be more aggressive than previously reported cases.
Molecular Diagnosis of <i>Taenia saginata</i> Tapeworm Infection in 2 Schoolchildren, Myanmar
Won, Eun Jeong,Jung, Bong-Kwang,Song, Hyemi,Kim, Mi-Seon,Kim, Hyun-Seung,Lee, Keon Hoon,Kim, Min-Jae,Shin, Myung Geun,Shin, Jong Hee,Suh, Soon-Pal,Hong, Sung-Jong,Sohn, Woon-Mok,Htoon, Thi Thi,Tin, Ht Centers for Disease Control and Prevention 2018 Emerging infectious diseases Vol.24 No.6
<P><I>Taenia saginata</I> is the most common human tapeworm worldwide but has been unknown in Myanmar. In 2017, fecal examination in Yangon, Myanmar, revealed eggs of <I>Taenia</I> species in 2 children from a monastic school. Several proglottids expelled after medication with praziquantel were morphologically and molecularly confirmed to be <I>T. saginata</I> tapeworms.</P>
AN EPIDEMIOLOGICAL OBSERVATION ON THE HEMORRHAGIC FEVER WITH RENAL SYDROME OF ZOONOSES IN KOREAN
Won Chang Lee,Soon Jae Kim,Tae Jong Kim,Ki Hong Lee,Takeo Sakai,Chong Sam Yoon 한국예방수의학회 1991 예방수의학회지 Vol.15 No.1
The author’s conducted an epidemiological observation on Korean hemorrhagic fever type of hemorrhagic fever with renal syndrome(HFRS) of zoonoses in Korean during the period from 1979 to 1988 for veterinary public health. The following results were summerized: The hemorrhagic fever with renal syndrome in Korean and the year of highest incidence rate was 0.19 per 100,000 population of 1979 and the year of higher case fatality rate was 19.44% of 1984. Since the nicidence case of HFRS is geographically distribution along the mountain-range after 1960 up to now, howerer, show that patients are widely distributed throughout the Korea with urban cities having great number of cases. The seasonal incidence cases in percent of total HFRS cases in order autumn, winter, summer and spring were 75.2%, 19.13%, 4.45% and 1.02%, respectively. Hemorrhagic fever with renal syndrome appears to most frequency affect person 20 to 59 years old.
( Soon Ha Kwon ),( Soung Won Jeong ),( Jae Young Jang ),( Ji Eun Lee ),( Sae Hwan Lee ),( Sang Gyune Kim ),( Young Seok Kim ),( Young Deok Cho ),( Hong Soo Kim ),( Boo Sung Kim ),( So Young Jin ) 대한간학회 2012 Clinical and Molecular Hepatology(대한간학회지) Vol.18 No.3
Background/Aims: Cyclooxygenase-2 (COX-2) and vascular endothelial growth factor (VEGF) are up-regulated in hepatocellular carcinoma (HCC). To investigate the levels of COX-2 and VEGF expression in chronic hepatitis (CH), cirrhosis, and HCC. Methods: The immunohistochemical expressions of COX-2 and VEGF were evaluated in tissues from patients with CH (n=95), cirrhosis (n=38), low-grade HCC (LG-HCC; n=6), and high-grade HCC (HG-HCC; n=29). Results: The COX-2 expression scores in CH, cirrhosis, LG-HCC, and HG-HCC were 3.3±1.9 (mean±SD), 4.2±1.7, 5.5±1.0, and 3.4±2.4, respectively (CH vs. cirrhosis, P=0.016; CH vs. LG-HCC, P=0.008; LG-HCC vs. HG-HCC, P=0.004), and the corresponding VEGF expression scores were 0.9±0.8, 1.5±0.7, 1.8±0.9, and 1.6±1.1 (CH vs. cirrhosis, P<0.001; CH vs. LGHCC, P=0.011; LG-HCC vs. HG-HCC, P=0.075). Both factors were correlated with the fibrosis stage in CH and cirrhosis (COX-2: r=0.427, P<0.001; VEGF: r=0.491, P<0.001). There was a significant correlation between COX-2 and VEGF in all of the tissue samples (r=0.648, P<0.001), and between high COX-2 and VEGF expression scores and survival (COX-2: P=0.001; VEGF: P<0.001). Conclusions: The expressions of both COX-2 and VEGF are significantly higher in cirrhosis and LG-HCC than in CH. High COX-2 and high VEGF expressions are associated with a high survival rate. (Clin Mol Hepatol 2012;18:287-294)