실험계획법을 이용한 텔레매틱스 HMI 평가에 관한 연구

신희종(Heejong Shin),유시복(Sibok Ryu),우진명(Jinmyung Woo),천환규(Hwankyu Chun),이장일(Jangil Lee),서명원(Myungwon Suh) 한국자동차공학회 2009 한국자동차공학회 학술대회 및 전시회 Vol.2009 No.11

Recently, telematics devices have been used for driver’s safety and convenience .Telematics market including navigation is getting bigger and bigger. However, traffic accident from using telematics equipment is also increasing. Drivers may lose glance using navigation, and driver’s workload will also grow by driver’s distraction. This thesis is base on the study about the influence on the driver’s workload according to combination of display by DOE(design of experiment). The main object of this thesis is measuring the workload according to the telematics usage by HMI (Human Machine Interface) in the virtual reality. The result of these experiments is that workload when driver used navigation was different with a style of text type. Also, it confirmed the significant result from the statistics analysis.

A_(3) Adenosine Receptor Antagonist, Truncated Thio-CI-IB- MECA, Induces Apoptosis in T24 Human Bladder Cancer Cells

김희종,강정우,이소정,최원준,정낙신,Young Yang,홍진태,윤도영 Sookmyung Women's University Research Institute of 2010 여성과 건강 Vol.6 No.1

A_(3) Adenosine Receptor Antagonist, Truncated Thio-CI-IB- MECA, Induces Apoptosis in T24 Human Bladder Cancer Cells

김희종,강정우,이소정,최원준,정낙신,Young Yang,홍진태,윤도영 Sookmyung Women's University Research Institute of 2010 여성과 건강 Vol.6 No.1

IPlace 시스템에서의 공개 작업공간 지원

박희종(Heejong Park),김진홍(Jinhong Kim),신원준(Wonjoon Shin),박양수(Yangsu Park),이명준(Myungjoon Lee) 한국정보과학회 2004 한국정보과학회 학술발표논문집 Vol.31 No.1A

IPlace 시스템은 등록된 사용자 사이에서 효과적인 공동작업을 지원하는 웹 기반 협업지원 시스템이다. 현재 개발된 IPlace 시스템은 자주 일어나는 공동작업을 등록된 사용자가 생성한 팀작업장을 통해서만 지원하고 있으므로 시스템에 등록하지 않은 사용자와의 효율적인 자료공유는 제공하지 못하고 있다. 본 논문에서는 이러한 문제점을 해결하기 위해서 IPlace 시스템에 등록하지 않은 사용자에게 효과적인 공동 작업을 지원하기 위한 공개 작업공간인 OpenSpace에 대하여 기술한다. IPlace 시스템에 제안된 OpenSpace를 제공함으로써 기존의 IPlace 사용자와 등록되지 않은 사용자 사이의 자유롭고 편리한 자료공유 기능을 제공할 수 있다. OpenSpace는 플랫폼 독립적인 JSP 및 EJB 컴포넌트 기술을 이용하여 개발되었다.

A3 Adenosine Receptor Antagonist, Truncated Thio-Cl-IB-MECA, Induces Apoptosis in T24 Human Bladder Cancer Cells.

Kim, Heejong,Kang, Jeong Woo,Lee, Sojung,Choi, Won Jun,Jeong, Lak Shin,Yang, Young,Hong, Jin Tae,Yoon, DO Young Potamitis Press 2010 Anticancer research Vol.30 No.7

<P>BACKGROUND: Human A(3) adenosine receptor (A(3)AR) plays an essential role in several physiopathological processes. Thus far, A(3)AR-selective ligands have been evaluated as anti-inflammation and anticancer therapeutic agents. Among these ligands, truncated thio-Cl-IB-MECA is a newly reported antagonist, and its function has not been studied. MATERIALS AND METHODS: Cell viability was measured by MTS assay. Cell cycle progression was analysed by propidium iodide (PI) flow cytometric assay. The apoptotic effects were investigated by Hoechst staining and annexin V-FITC/PI staining. The signal-transduction mechanism was explored by Western blot. RESULTS: Truncated thio-Cl-IB-MECA induced the growth arrest of T24 cells at sub-G(1) phase and provoked apoptosis but not necrosis. Apoptotic death was mediated by the activation of extracellular signal-regulated kinase (ERK) and c-Jun N-terminal kinase (JNK). CONCLUSION: Since truncated thio-Cl-IB-MECA induces anti-proliferation and apoptotic effects via ERK and JNK activation, it may function as an anticancer agent in human bladder cancer cells.</P>

인천지역 기후변화에 따른 미세먼지의 건강 취약성 평가

유희종(Heejong Yoo),김정곤(Jongkon Kim),신재원(Jaewon Shin),김영주(Youngju Kim),민성은(Sungeun Min),제갈대성(Daesung Jegal),방기인(Kiin Bang),이성모(Sungmo Lee) 한국환경보건학회 2017 한국환경보건학회지 Vol.43 No.3

Objectives: This study was conducted to evaluate the vulnerability of the human health sector to PM 10 due to climate change in Incheon over the period of 2005-2014. Methods: Vulnerability to PM 10 consists of the three categories of climate exposure, sensitivity, and adaptive capacity. The indexes for climate exposure and sensitivity indicate positive effects, while adaptive capacity shows a negative effect on vulnerability to PM 10 . The variables in each category were standardized by the rescaling method, and respective relative regional vulnerability was analyzed through the vulnerability index calculation formula of the Intergovernmental Panel on Climate Change. Results: Regions with a high exposure index were the western and northern urban areas with industrial complexes adjacent to a highway, including Bupyong-gu and Seo-gu. Major factors determining the climate exposure index were the PM 10 concentration, days of PM 10 3 , and PM 10 emissions. The regions showing a high sensitivity index were urban regions with high populations; these commonly had a high mortality rate for related diseases and vulnerable populations. Conclusions: This study is able to support regionally adjusted adaptation policies and the quantitative background of policy priority since it provides information on the regional health vulnerability to PM 10 due to climate change in Incheon.

7 Series FPGA Transceiver IP 기반의 High-Speed Serial Transceiver 설계 및 검증

유희종(Heejong Yu),신동욱(Dongwook Shin) 항공우주시스템공학회 2023 항공우주시스템공학회 학술대회 발표집 Vol.2023 No.10

WebDAV기반 협업시스템의 클라이언트 개발

신원준(Wonjoon Shin),박희종(HeeJong Park),김동호(DongHo Kim),박양수(YangSoo Park),이명준(Myungjoon Lee) 한국정보과학회 2005 한국정보과학회 학술발표논문집 Vol.32 No.1

WebDAV는 웹통신 프로토콜인 HTTP/1.1의 확장으로서 인터넷을 통하여 다양한 자원의 비동기적인 협업을 지원하는 표준 프로토콜이다. CoSlide 시스템은 협업을 효과적으로 지원하기 위하여 WebDAV 프로토콜을 확장하여 개발된 협업시스템이다. CoSlide 협업시스템은 협업을 위한 가상공간을 제공하며 가상공간에 다양한 자원을 등록 및 관리할 수 있다. CoSlide 협업시스템을 활용하여 효과적인 협업을 수행하기 위한 사용자 중심의 클라이언트가 필요하다. 본 논문에서는 WebDAV 프로토콜을 이용한 협업시스템인 CoSlide를 효과적으로 활용하기 위한 클라이언트 개발에 대하여 기술한다. 개발된 클라이언트는 사용자가 서버에 등록한 자원을 관리하는 기능과 팀원들 간의 상호작용을 원활하게 지원하는 사용자 인터페이스를 제공한다. 또한 CoSlide 협업시스템을 사용하는 사용자는 새로운 작업장을 생성하고 다른 사용자를 초대할 수 있으며, 작업장에 파일을 등록, 이동 그리고 삭제할 수 있다. 기존의 협업시스템에서 분산저작을 하는 경우 클라이언트에서 제공하는 특정 프로그램을 이용하거나, 파일을 서버로부터 내려받아 이를 수정하여 다시 등록하는 과정을 거친다. 본 클라이언트는 이러한 단점을 개선하여 CoSlide 협업시스템의 자원에 대하여 다양한 저작프로그램을 자동적으로 연결하여주며, 실시간으로 협업시스템의 자원을 갱신하여 준다. 또한 자원에 대한 일관성을 보장하기 위하여 자동 잠금기능을 제공한다. 추가적으로 사용자는 드래그앤드랍 기능을 이용하여 작업장간의 자원을 이동할 수 있다.

Transformation of methylparaben during water chlorination: Effects of bromide and dissolved organic matter on reaction kinetics and transformation pathways

Yoom, Hoonsik,Shin, Jaedon,Ra, Jiwoon,Son, Heejong,Ryu, Dongchoon,Kim, Changwon,Lee, Yunho Elsevier BV 2018 Science of the Total Environment Vol.634 No.-

<P><B>Abstract</B></P> <P>The reaction kinetics, products, and pathways of methylparaben (MeP) during water chlorination with and without bromide (Br<SUP>−</SUP>) were investigated to better understand the fate of parabens in chlorinated waters. During the chlorination of MeP-spiked waters without Br<SUP>−</SUP>, MeP was transformed into mono-Cl-MeP and di-Cl-MeP with apparent second-order rate constants (<I>k</I> <SUB>app</SUB>) of 64M<SUP>−1</SUP> s<SUP>−1</SUP> and 243M<SUP>−1</SUP> s<SUP>−1</SUP> at pH7, respectively, while further chlorination of di-Cl-MeP was relatively slower (<I>k</I> <SUB>app</SUB> =1.3M<SUP>−1</SUP> s<SUP>−1</SUP> at pH7). With increasing Br<SUP>−</SUP> concentration, brominated MePs, such as mono-Br-MeP, Br-Cl-MeP, and di-Br-MeP, became major transformation products. The di-halogenated MePs (di-Cl-MeP, Br,Cl-MeP, and di-Br-MeP) showed relatively low reactivity to chlorine at pH7 (<I>k</I> <SUB>app</SUB> =1.3–4.6M<SUP>−1</SUP> s<SUP>−1</SUP>) and bromine (<I>k</I> <SUB>app</SUB> =32–71M<SUP>−1</SUP> s<SUP>−1</SUP>), which explains the observed high stability of di-halogenated MePs in chlorinated waters. With increasing pH from 7 to 8.5, the transformation of di-halogenated MePs was further slowed due to the decreasing reactivity of di-MePs to chlorine. The formation of the di-halogenated MePs and their further transformation become considerably faster at Br<SUP>−</SUP> concentrations higher than 0.5μM (40μg/L). Nonetheless, the accelerating effect of Br<SUP>−</SUP> diminishes in the presence of dissolved organic matter (DOM) extract (Suwannee River humic acid (SRHA)) due to a more rapid consumption of bromine by DOM than chlorine. The effect of Br<SUP>−</SUP> on the fate of MeP was less in the tested real water matrices, possibly due to a more rapid bromine consumption by the real water DOM compared to SRHA. A kinetic model was developed based on the determined species-specific second-order rate constants for chlorination/bromination of MeP and its chlorinated and brominated MePs and the transformation pathway information, which could reasonably simulate the transformation of MePs during the chlorination of water in the presence of Br<SUP>−</SUP> and selected DOM.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Transformation kinetics and pathways of methylparaben during chlorination are studied. </LI> <LI> Second-order rate constants for chlorine/bromine with methylparabens are reported. </LI> <LI> Brominated methylparabens are dominant over chlorinated ones with increasing bromide. </LI> <LI> Bromide effect on methylparaben transformation diminishes by dissolved organic matter. </LI> <LI> The developed kinetic model can simulate the paraben transformation in chlorination. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>

Elimination efficiency of organic UV filters during ozonation and UV/H₂O₂ treatment of drinking water and wastewater effluent

Seo, Changdong,Shin, Jaedon,Lee, Minju,Lee, Woongbae,Yoom, Hoonsik,Son, Heejong,Jang, Seongho,Lee, Yunho Elsevier 2019 CHEMOSPHERE - Vol.230 No.-

<P><B>Abstract</B></P> <P>The efficiency of elimination of organic UV filters by ozonation and UV<SUB>254nm</SUB>/H<SUB>2</SUB>O<SUB>2</SUB> processes was assessed and predicted in simulated treatments of sewage-impaired drinking water and wastewater effluent in bench-scale experiments. Second-order rate constants (<I>k</I>) for the reactions of the eight UV filters with ozone and OH were determined by quantum chemical calculations and competition kinetics methods, respectively. The UV filters containing phenolic (ethylhexyl-salicylate, homosalate, and benzophenone-3) and olefinic moieties (4-methylbenzylidene-camphor, benzyl-cinnamate, and 2-ethylhexyl-4-methoxycinnamate) showed high ozone reactivity (<I>k</I> ≥ 8 × 10<SUP>4</SUP> M<SUP>−1</SUP>s<SUP>−1</SUP> at pH 7), while those without such electron-rich moieties (isoamyl-benzoate and benzophenone) were ozone-refractory. All the UV filters showed high OH reactivity (<I>k</I> ≥ 6.2 × 10<SUP>9</SUP> M<SUP>−1</SUP>s<SUP>−1</SUP>). In concordance with the rate constant information, the phenolic and olefinic UV filters were efficiently eliminated by ozone treatment, requiring specific ozone doses of <0.5 mgO<SUB>3</SUB>/mgDOC for ∼100% elimination. The UV filters were eliminated by ≤ 38% at a UV fluence of 1500 mJ/cm<SUP>2</SUP> in the UV<SUB>254nm</SUB>-only treatment. Rapid photoisomerisation between the <I>E</I> and <I>Z</I> geometric isomers was observed for the olefinic UV filter, benzyl-cinnamate. The addition of H<SUB>2</SUB>O<SUB>2</SUB> (10 mg/L) greatly enhanced the elimination of all UV filters, indicating that OH was the main contributor to their elimination in the UV<SUB>254nm</SUB>/H<SUB>2</SUB>O<SUB>2</SUB> treatment. A chemical kinetics approach developed previously for ozonation and UV/H<SUB>2</SUB>O<SUB>2</SUB> processes was shown to predict the elimination of the UV filters in the tested water matrices reasonably well, demonstrating that the chemical kinetics method can be used for a priori prediction of micropollutant elimination in oxidative treatment processes for potable reuse of municipal wastewater effluents.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Reaction kinetics were determined for ozone, .OH, and UV<SUB>254nm</SUB> with organic UV filters </LI> <LI> Phenolic & olefinic UV filters show high ozone reactivity and efficient elimination. </LI> <LI> Rapid photo-isomerisation occurs for the olefinic UV filters. </LI> <LI> .OH is mainly responsible for the elimination of UV filters in UV<SUB>254nm</SUB>/H<SUB>2</SUB>O<SUB>2</SUB> treatment </LI> <LI> The chemical kinetics method allows a priori prediction of micropollutant elimination. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>