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Jia, Xiyuan,Zhang, Xinwu,Jing, Jiangchao,Zhou, Ming,Li, Haoyang,Friesen, Dimitris,Ma, Yue 서울대학교 교육연구소 2022 Asia Pacific Education Review Vol.23 No.1
Rural China has seen an increase in its migrant workers returning home. As a result, many of these workers’ children, who had previously boarded at school, needed to return home as well. While the existing research indicates that boarding affects the development of disadvantaged children, the effect of the switch to nonboarding on the growth of vulnerable boarding children remains unknown. Using two-stage data from 20,594 fourth- and fifth-grade students in rural Shaanxi and Gansu provinces as well as the difference-in-differences method, this study estimates the impact of switching to nonboarding on the academic performance and mental health of vulnerable boarding students. The results suggest that the shift toward nonboarding significantly reduces boarding students’ academic performance, and further testing shows that these results are robust. Additionally, the switch to nonboarding insignificantly increased the standardized mental health scores of rural primary school students but significantly increased their standardized impulsive tendency scores. Heterogeneity analysis found that boarding students whose mothers had lower educational achievement or whose families belonged to lower economic levels had poorer academic performance after switching, while boarding students whose parents had higher education achievement or myopia possessed better mental health after switching. This study offers novel, policy-relevant insights into potential strategies that would improve the academic performance and mental health of students who transition to nonboarding, especially those with low-educated parents and those belonging to poor families.
Hongwei Geng,Linlin Hao,Yunyun Cheng,Chunli Wang,Wenzhen Wei,Rui Yang,Haoyang Li,Ying Zhang,Songcai Liu 아세아·태평양축산학회 2020 Animal Bioscience Vol.33 No.10
Objective: This study aimed to elucidate the effect of miR-140 on the proliferation of porcine fetal fibroblasts (PFFs) and identify the target genes of miR-140 in PFFs. Methods: In this study, bioinformatics software was used to predict and verify target genes of miR-140. Quantitative polymerase chain reaction and western blot were used to detect the relationship between miR-140 and its target genes in PFFs. Dual luciferase reporter gene assays were performed to assess the interactions among miR-140, type 1 insulin-like growth factor receptor (IGF1R), and SRY-box 4 (SOX4). The effect of miR-140 on the proliferation of PFFs was measured by CCK-8 when PFFs were transfected with a miR-140 mimic or inhibitor. The transcription factor SOX4 binding to promoter of IGF1R was detected by chromatin immunoprecipitation assay (ChIP). Results: miR-140 directly targeted IGF1R and inhibited proliferation of PFFs. Meanwhile, miR-140 targeted transcription factor SOX4 that binds to promoter of porcine IGF1R to indirectly inhibit the expression of IGF1R. In addition, miR-140 inhibitor promoted PFFs proliferation, which is abrogated by SOX4 or IGF1R knockdown. Conclusion: miR-140 inhibited PFFs proliferation by directly targeting IGF1R and indirectly inhibiting IGF1R expression via SOX4, which play an important role in the development of porcine fetal.
Hao Yang,Bin Mu,Shue Li,Naidi Wang,Aiping Hui,Aiqin Wang 한국공업화학회 2022 Journal of Industrial and Engineering Chemistry Vol.112 No.-
To reduce the wastes discharging and production cost for preparation of cobalt blue pigments via commonliquid-phase methods, the low-cost and high-chroma cobalt blue composite pigments are fabricatedvia CaCO3-assisted mechanochemical route followed by an annealing process based on the discarded kaolintailing sand (KTS) from the mineral processing. The preparation conditions, formation and coloringmechanisms of composite pigments are studied systematically. The optimal color performance(L* = 40.54, a* = 4.12, b* = 55.22) is obtained after optimizing the preparation conditions. The resultsindicate that CaCO3 acts as a mild precipitant with the assistance of mechanochemical effects to formthe precursor. Furthermore, incorporation of KTS improves the color lightness and blueness of cobalt bluepigments due to the reflection of KTS toward light and well dispersion of CoAl2O4 on KTS surface. Compared with the commercial cobalt blue pigments, the oil absorption and hiding power of compositepigments are high while the relative tinting strength slightly reduces owing to the differences in theirsize and CoAl2O4 content, but the composite pigments may be more popular due to the low productioncost and excellent color performance. Moreover, the as-prepared composite pigments present excellentacid-resistance and coloring performance as a ceramic pigment.