Low temperature HFCVD synthesis of tungsten oxide thin film for high response hydrogen gas sensor application

Godbole, Rhushikesh,Ameen, Sadia,Nakate, Umesh T.,Shaheer Akhtar, M.,Shin, Hyung-Shik Elsevier 2019 Materials letters Vol.254 No.-

<P><B>Abstract</B></P> <P>A quick and efficient approach was employed for the growth of nanocrystalline tungsten oxide (WO<SUB>3</SUB>) thin films using one-step hot filament chemical vapor deposition (HFCVD) method at low temperature. In a typical experiment, the parent material tungsten (W) was subjected to oxidation, gasification and its subsequent condensation to obtain the uniform deposition of WO<SUB>3</SUB> thin film on silicon substrate at significantly low temperature of ∼200 °C. Prepared WO<SUB>3</SUB> thin film possessed the cauliflower nanostructure (WCNs) with typical monoclinic WO<SUB>3</SUB> crystal structure. Prepared WCNs thin films were applied for the detection of hydrogen (H<SUB>2</SUB>) gas at 100 ppm. H<SUB>2</SUB> response increased with rise in temperature and the maximum response of ∼87% was obtained at the optimized temperature of ∼250 °C with response time 180 s.</P> <P><B>Highlights</B></P> <P> <UL> <LI> WO<SUB>3</SUB> thin films are obtained through low temperature HFCVD technique. </LI> <LI> WO<SUB>3</SUB> thin films exhibits cauliflower morphology (WCNs) with typical monoclinic WO<SUB>3</SUB> crystal structure. </LI> <LI> Highly uniform WCNs thin film is prepared. </LI> <LI> High sensitivity of ∼87% towards H<SUB>2</SUB> gas is achieved. </LI> </UL> </P>

Hot filament chemical vapour deposition processing of titanate nanotube coatings

Godbole, V P,Kim, G S,Dar, M A,Kim, Y S,Seo, H K,Khang, G,Shin, H S IOP Pub 2005 Nanotechnology Vol.16 No.8

<P>In the present paper, we report on the processing of titanate nanotubes using the hot filament chemical vapour deposition (HF-CVD) method to synthesize titania–carbon nanotube–wire composites. The titanate nanotubes are prepared using a chemical route, and then deposited on <img SRC='http://ej.iop.org/images/0957-4484/16/8/035/nano197486ieqn1.gif' ALIGN='MIDDLE' ALT='\langle 100\rangle '/> silicon using an electrodeposition method. The HF-CVD is used to process these coatings at different temperatures in vacuum as well as in different concentrations of hydrogen (H<SUB>2</SUB>) and methane (CH<SUB>4</SUB>) gas mixtures. The evolutions of the surface and precipitation for various phases have been monitored using different characterization techniques. It is observed that titanate nanotubes start disintegrating above <I>T</I><SUB>s</SUB>∼500 ?C, and exhibit different types of phase precipitation depending upon the temperature and gas ambient. Under appropriate conditions, the presence of activated hydrogen and carbon radicals leads to the formation of novel architectures of mixtures of nanophases such as carbide, nonstoichiometric titania, carbon nanotubes, and titania decorated carbon nanowires. The results are discussed in terms of reduction in the thermal reaction barrier due to the presence of atomic hydrogen, and the formation of energetic sites during disintegration of titania nanotubes to facilitate nucleation of nanotube and nanowire structures.</P>

Virechana karma (therapeutic purgation) in the restoration of gut microbiota concerning Amavata (RA): A scientific exposition

Godbole, Amrit,Sweta, Sweta,Abhinav, Abhinav,Singh, O.P. Cellmed Orthocellular Medicine and Pharmaceutical 2021 셀메드 (CellMed) Vol.11 No.1

Background: Amavata is a disease that occurs as a result of the error of metabolism. Poor dietary habits and faulty Dincharya (daily regimen) and ritucharya (seasonal regimen) leading to deranged metabolism and Agni (metabolic fire) which results in the formation of Ama(undigested product of metabolism). When Amaconceals with Vata(subtle energy associated with movement) and circulates in the body under the influence of Vyana Vayu (omnipresent air)it clogs the srotasas (microchannels) and initiates the inflammatory cascade. Amavata is commonly correlated with rheumatoid arthritis (RA) while other forms of auto-immune disorders can also be included in Amavata.Dysbiosis of the gut microbiota (GM) has been connected to the onset of diverse autoimmune diseases. In this study, it was hypothesized that Panchakarma (bio-purificatory methods) based intervention such as Virechana Karma (therapeutic purgation) may influence microbiota. Materials and Methods: Various Ayurvedic literature were reviewed for the etiopathogenesis of Amavata. Different databases were searched with research papers related to Gut Dysbiosis and autoimmunity and management of RA. A connecting link between Intestinal Dysbiosis with the autoimmune mechanisms was established and it was also found that the bowel cleansing introduced a change to the GM. Conclusion: It was concluded that Virechana karma is effective in gut flora Dysbiosis. This study aims to correlate the ancient Ayurvedic principles related to Agni Bala(metabolic energy) and biopurificatory treatment modalities like Virechana karma (therapeutic purgation)with the modern concept of gut microbiota and its role in the pathogenesis of various autoimmune disorders such as rheumatoid arthritis. The article creates an understanding about principles of Ayurveda and its rationality in today's scientific world and thereby opens newer vistas of research in therapeutics from Ayurveda, which may be helpful in the management of various immune-mediated Diseases through Ayurveda.

Application of artificial neural network for determination of wind induced pressures on gable roof

Kwatra, Naveen,Godbole, P.N.,Krishna, Prem Techno-Press 2002 Wind and Structures, An International Journal (WAS Vol.5 No.1

Artificial Neural Networks (ANN) have the capability to develop functional relationships between input-output patterns obtained from any source. Thus ANN can be conveniently used to develop a generalised relationship from limited and sometimes inconsistent data, and can therefore also be applied to tackle the data obtained from wind tunnel tests on building models with large number of variables. In this paper ANN model has been developed for predicting wind induced pressures in various zones of a Gable Building from limited test data. The procedure is also extended to a case wherein interference effects on a gable roof building by a similar building are studied. It is found that the Artificial Neural Network modelling is seen to predict successfully, the pressure coefficients for any roof slope that has not been covered by the experimental study. It is seen that ANN modelling can lead to a reduction of the wind tunnel testing effort for interference studies to almost half.

Application of artificial neural network for determination of wind induced pressures on gable roof

Naveen Kwatra,P.N. Godbole,Prem Krishna 한국풍공학회 2002 Wind and Structures, An International Journal (WAS Vol.5 No.2

Plasma enhanced chemical vapor deposition of palladium in anodic aluminum oxide template

Young-Soon Kim,V.P. Godbole,Joong-Hee Cho,Gilson Khang,Hyung-Shik Shin 한국물리학회 2006 Current Applied Physics Vol.6 No.1l

High quality AAO templates were fabricated using multi-step electrochemical process. The formation of well ordered pores havingdimensions of 50100 nm diameters and up to 2000 nm depths, could be achieved. The eect of processing time, voltage during anod-vapor deposition using palladium hexauro-acetylacetonate [Pd(C5HF6O2)2], as a precursor material. The samples were characterizedby using high resolution scanning electron microscopy (SEM), energy dispersive X-ray analysis (EDX), glancing angle X-ray diractionetc. It is observed that the conformal coatings of palladium could be achieved in AAO pores, which could subsequently be utilized formany applications where in catalytic behavior of palladium is utilized.

The tensile deformation and fracture behavior of a magnesium alloy nanocomposite reinforced with nickel

Srivatsan, T.S.,Manigandan, K.,Godbole, C.,Paramsothy, M.,Gupta, M. Techno-Press 2012 Advances in materials research Vol.1 No.3

In this paper the intrinsic influence of micron-sized nickel particle reinforcements on microstructure, micro-hardness tensile properties and tensile fracture behavior of nano-alumina particle reinforced magnesium alloy AZ31 composite is presented and discussed. The unreinforced magnesium alloy (AZ31) and the reinforced nanocomposite counterpart (AZ31/1.5 vol.% $Al_2O_3$/1.5 vol.% Ni] were manufactured by solidification processing followed by hot extrusion. The elastic modulus and yield strength of the nickel particle-reinforced magnesium alloy nano-composite was higher than both the unreinforced magnesium alloy and the unreinforced magnesium alloy nanocomposite (AZ31/1.5 vol.% $Al_2O_3$). The ultimate tensile strength of the nickel particle reinforced composite was noticeably lower than both the unreinforced nano-composite and the monolithic alloy (AZ31). The ductility, quantified by elongation-to-failure, of the reinforced nanocomposite was noticeably higher than both the unreinforced nano-composite and the monolithic alloy. Tensile fracture behavior of this novel material was essentially normal to the far-field stress axis and revealed microscopic features reminiscent of the occurrence of locally ductile failure mechanisms at the fine microscopic level.

Curcumin Conjugates Induce Apoptosis Via a Mitochondrion Dependent Pathway in MCF-7 and MDA-MB-231 Cell Lines

Singh, Durg Vijay,Agarwal, Shikha,Singh, Preeti,Godbole, Madan Madhav,Misra, Krishna Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.10

In order to enhance the bioavailability of curcumin its conjugates with piperic acid and glycine were synthesized by esterifying the 4 and 4' phenolic hydroxyls, the sites of metabolic conjugation. Antiproliferative and apoptotic efficacy of synthesized conjugates was investigated in MCF-7 and MDA-MB-231 cell lines. $IC_{50}$ values of di-O-glycinoyl (CDG) and di-O-piperoyl (CDP) esters of curcumin were found to be comparable with that of curcumin. Both conjugates induced chromatin condensation fragmentation and apoptotic body formation. CDP exposure to MCF-7 cells induced apoptosis initiating loss of mitochondrial membrane potential (${\Delta}{\Psi}m$) followed by inhibition of translocation of transcription factor NF-${\kappa}B$ and release of Cytochrome-C. Reactive oxygen species (ROS) production was evaluated by fluorescent activated cell sorter. Change in ratio of Bcl2/Bclxl was observed, suggesting permeablization of mitochondrial membrane leading to the release of AIF, Smac and other apoptogenic molecules. DNA fragmentation as a hallmark for apoptosis was monitored by TUNEL as well as agrose gel electrophoresis. Thus, it was proven that conjugation does not affect the therapeutic potential of parent molecule in vitro, while these could work in vivo as prodrugs with enhanced pharmacokinetic profile. Pharmacokinetics of these molecules under in vivo conditions is a further scope of this study.

A comparative study of smica in various body fluids of diagnosed cervical cancer patients and healthy women

( Pooja A. Pachani ),( Rajendra R. Godbole ),( Jeevitaa Kshersagar ),( Rakhi Jagdale ),( Amita Gosavi ),( Somshekhar Patil ),( Rakesh K Sharma ),( Meghnad G. Joshi ) 대한산부인과학회 2022 Obstetrics & Gynecology Science Vol.65 No.1

Objective Cervical cancer (CC) is a major public health problem in women, and its early detection can help reduce morbidity and mortality. The objective of this study was to compare serum levels of soluble major histocompatibility complex class I-related chain A (sMICA) levels in various body fluids between women diagnosed with CC and healthy women. Methods A case-control study was conducted at a tertiary care hospital and a cancer center in Kolhapur, India. Overall, 150 individuals (100 CC patients and 50 healthy women) participated after providing informed written consent. Demographic data, histopathology history, parity, and tumor, node, and metastasis (TNM) staging data were collected. Pap smears, saliva, blood, and urine samples were collected. Pap smears were examined microscopically, and sMICA levels in all samples were determined by enzyme-linked immunoassay (ELISA). Results The mean age of women with cervical cancer was 49.86±8.18 years. Squamous cell carcinoma (70%) was the most common histological variant in CC patients. Serum soluble sMICA levels differed significantly with parity and TNM staging (P<0.05). Mean levels of sMICA were significantly different in samples (CC cases vs. healthy patients; saliva: 166.721±108.718 vs. 0.039±0.005 pg/mL; urine: 82.921±45.580 vs. 0.010±0.005 pg/mL; serum: 35.756±10.799 vs. 0.039±0.005 pg/mL, P<0.001). Conclusion Levels of sMICA in body fluids can be considered as a diagnostic or prognostic tool to determine disease progression or tumor regression.