Assessing the effects of mineral content and porosity on ultrasonic wave velocity

Fereidooni, Davood Techno-Press 2018 Geomechanics & engineering Vol.14 No.4

The influences of mineral content and porosity on ultrasonic wave velocity were assessed for ten hornfelsic rocks collected from southern and western parts of the city of Hamedan, western Iran. Selected rock samples were subjected to mineralogical, physical, and index laboratory tests. The tested rocks contain quartz, feldspar, biotite, muscovite, garnet, sillimanite, kyanite, staurolite, graphite and other fine grained cryptocrystalline matrix materials. The values of dry unit weight of the rocks were high, but the values of porosity and water absorption were low. In the rocks, the values of dry unit weight are related to the presence of dense minerals such as garnet so not affected by porosity. The statistical relationships between mineral content, porosity and ultrasonic wave velocity indicated that the porosity is the most important factor influencing ultrasonic wave velocity of the studied rocks. The values of P-wave velocity of the rocks range from moderate to very high. Empirical equations, relevant to different parameters of the rocks, were proposed to determine the rocks' essential characteristics such as primary and secondary wave velocities. Quality indexes (IQ) of the studied samples were determined based on P-wave velocities of them and their composing minerals and the samples were classified as non-fissured to moderately fissured rocks. Also, all tested samples are classified as slightly fissured rocks according to the ratio of S-wave to P-wave velocities.

The effect of bee prepolis on primary dysmenorrhea: a randomized clinical trial

Ensiyeh Jenabi,Bita Fereidooni,Manoochehr Karami,Seyedeh Zahra Masoumi,Mahdi Safari,Salman Khazaei 대한산부인과학회 2019 Obstetrics & Gynecology Science Vol.62 No.5

ObjectivePrimary dysmenorrhea typically occurs with no associated pelvic pathology and is common in adolescents and youngwomen. This study evaluated the effect of bee propolis on relief of primary dysmenorrhea. MethodsThe study was performed in 2018 in Hamadan, in western Iran, among female students with primary dysmenorrhea. Participants were randomly divided into two groups, using balanced block randomization, and were administereda placebo or bee propolis capsules for 5 days during two menstruation cycles. The number of participants requiredwas estimated to be 86 in total, with 43 students in each group according to the inclusion criteria. We used the visualanalog scale to assess pain severity. The independent t-test was conducted for comparing between two groups, usingSPSS 16.0. ResultsA significant change was found in the mean pain scores during the first (P<0.001) and second (P<0.001) months afterusing bee propolis in comparison with placebo. The means of the pain scores in the bee propolis group were 5.32±2.28and 4.74±2.40 in first and second months after the intervention, respectively, whereas the means of the pain scores inthe placebo group were 7.40±1.21 and 7.17±1.24 in first and second months after the intervention, respectively. ConclusionOur study showed that the use of bee propolis for two months compared with placebo reduced primary dysmenorrheaduring the first and second months after use, with no adverse effects. Therefore, it could be used as an alternative tononsteroidal anti-inflammatory drugs for relief of primary dysmenorrhea.

Association of Poor Prognosis Subtypes of Breast Cancer with Estrogen Receptor Alpha Methylation in Iranian Women

Izadi, Pantea,Noruzinia, Mehrdad,Fereidooni, Foruzandeh,Nateghi, Mohammad Reza Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.8

Breast cancer is a prevalent heterogeneous malignant disease. Gene expression profiling by DNA microarray can classify breast tumors into five different molecular subtypes: luminal A, luminal B, HER-2, basal and normal-like which have differing prognosis. Recently it has been shown that immunohistochemistry (IHC) markers including estrogen receptor (ER), progesterone receptor (PR) and human epidermal growth factor receptor 2 (Her2), can divide tumors to main subtypes: luminal A (ER+; PR+/-; HER-2-), luminal B (ER+;PR+/-; HER-2+), basal-like (ER-;PR-;HER2-) and Her2+ (ER-; PR-; HER-2+). Some subtypes such as basal-like subtype have been characterized by poor prognosis and reduced overall survival. Due to the importance of the ER signaling pathway in mammary cell proliferation; it appears that epigenetic changes in the $ER{\alpha}$ gene as a central component of this pathway, may contribute to prognostic prediction. Thus this study aimed to clarify the correlation of different IHC-based subtypes of breast tumors with $ER{\alpha}$ methylation in Iranian breast cancer patients. For this purpose one hundred fresh breast tumors obtained by surgical resection underwent DNA extraction for assessment of their ER methylation status by methylation specific PCR (MSP). These tumors were classified into main subtypes according to IHC markers and data were collected on pathological features of the patients. $ER{\alpha}$ methylation was found in 25 of 28 (89.3%) basal tumors, 21 of 24 (87.5%) Her2+ tumors, 18 of 34 (52.9%) luminal A tumors and 7 of 14 (50%) luminal B tumors. A strong correlation was found between $ER{\alpha}$ methylation and poor prognosis tumor subtypes (basal and Her2+) in patients (P<0.001). Our findings show that $ER{\alpha}$ methylation is correlated with poor prognosis subtypes of breast tumors in Iranian patients and may play an important role in pathogenesis of the more aggressive breast tumors.

Lack of Detection of the Mouse Mammary Tumor-like Virus (MMTV) Env Gene in Iranian Women Breast Cancer using Real Time PCR

Tabriz, Hedieh Moradi,Zendehdel, Kazem,Shahsiah, Reza,Fereidooni, Forouzandeh,Mehdipour, Baharak,Hosseini, Zahra Mostakhdemin Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.5

Background: Mouse mammary tumor virus (MMTV) is the major cause of mammary tumors in mice. There is limited controversial evidence about the probable etiologic role of MMTV- like virus in human breast cancer. Materials and Methods: A total of 40 Formalin fixed paraffin embedded samples with diagnosis of breast cancer were collected in a period of 3 years from cancer institute of Iran. We selected both pre-menopausal and post-menopausal patients with different histologic grades and different ethnic groups. We evaluated presence of MMTV-like virus env gene through real time PCR method. Results: Forty patients (20 pre and 20 postmenopausal women) were evaluated with the mean age of 49.67. The average tumor size was 39 mm. None of the studied samples were positive for MMTV-like virus env gene target sequences. Conclusions: We found no evidence on the potential role of MMTV-like virus in the carcinogenicity of breast cancer among Iranian women.

Is there an association between labor induction and attention-deficit/hyperactivity disorder among children?

Jenabi, Ensiyeh,Seyedi, Mahdieh,Bashirian, Saeid,Fereidooni, Bita The Korean Pediatric Society 2021 Clinical and Experimental Pediatrics (CEP) Vol.64 No.9

Background: There is evidence of destructive effects of oxytocin use during labor on neurodevelopment. Purpose: This meta-analysis pooled all observational studies to determine the association between labor induction and the risk of attention-deficit/hyperactivity disorder (ADHD) among children. Methods: All observational studies (case-control and cohort) were reviewed until September 2020 after searches of the PubMed, Scopus, and Web of Science databases, the gray literature, and conference proceedings. The pooled odds ratios (ORs), relative ratios (RRs), and 95% confidence intervals (CI (swere calculated as random effect estimates of association among studies. Results: All observational studies were reviewed, including 4 cohort studies including 2,885,743 participants and 3 case-control studies including 51,135 participants (10,961 with ADHD and 40,174 in control groups) with a sample size of 2,936,878 participants. The pooled estimates of OR and RR did not indicate a significant association between labor induction and ADHD among children (OR, 1.13; 95% CI, 0.90-1.35) and (RR, 1.10; 95% CI, 0.96-1.24). Conclusions: The findings showed that labor induction is not associated with an increased risk of ADHD among children. However, more studies are needed to investigate the relationship between labor induction and ADHD.

Premixed filtration combustion of micron and sub-micron particles in inert porous media: A theoretical analysis

Mehdi Bidabadi,Majid Mafi,Jalil Fereidooni,Reza Tavakoli 한국화학공학회 2011 Korean Journal of Chemical Engineering Vol.28 No.2

An analytical model for one-dimensional premixed filtration combustion of volatile fuel particles-air mixture is presented. It is presumed that fuel particles first vaporize and a gaseous fuel with definite chemical structure is formed, which is subsequently oxidized in the gas phase. Flame structure is considered in the three zones. In the preheating vaporization zone, the mixture is heated until it reaches ignition temperature. In the reaction zone, the combustible mixture burns and the post flame zone is occupied by the combustion products. The temperature and mass fraction profiles are obtained of gaseous fuel in these three zones at a semi-infinite inert porous media. Thereafter, the effects of various parameters such as gas velocity, porosity, fuel particles diameter, number density of fuel particles, and heat of chemical reaction on the temperature and mass fraction profiles are investigated.

Expression Analysis of MiR-21, MiR-205, and MiR-342 in Breast Cancer in Iran

Savad, Shahram,Mehdipour, Parvin,Miryounesi, Mohammad,Shirkoohi, Reza,Fereidooni, Forouzandeh,Mansouri, Fatemeh,Modarressi, Mohammad Hossein Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.3

MicroRNAs (miRNAs) are short non-coding RNA molecules characterized by their regulatory roles in cancer and gene expression. We analyzed the expression of miR-21, miR-205, and miR-342 in 59 patients with breast cancer. Samples were divided into three different groups according to their immunohistochemistry (IHC) classification: ER- positive and/or PR-positive group ($ER^+$ and/or $PR^+$; group I); HER2-positive group ($HER^{2+}$; group II); and ER/ PR/ HER2- negative ($ER^-$/ $PR^-$/ $HER^{2-}$; group III) as the triple negative group. The expression levels of the 3 miRNAs were analyzed in the tumor samples and the compared with the normal neighboring dissected tumor (NNDT) samples in all three groups. The expression of miR-21 was similar in all three groups. In patients positive for P53 by IHC, positive for axillary lymph node metastasis and higher tumor stages, it appeared to have significantly elevated. However, significant increase was not found among the 18 fibroadenoma samples. Both miR-205 and miR-342 expressions were significantly down regulated in group III. We conclude that miR-21 does not discriminate between different breast cancer groups. In contrast, miR-205 and miR-342 may be used as potential biomarkers for diagnosis of triple negative breast cancer.