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- 검색키워드
- 저자 : Faramarzi, Farhad (검색결과 32 건)
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Faramarzi, Azita,Khalili, Mohammad Ali,Mangoli, Esmat The Korean Society for Reproductive Medicine 2019 Clinical and Experimental Reproductive Medicine Vol.46 No.3
Objective: It is widely accepted that aging decreases women's fertility capacity. The aim of this study was to assess correlations between maternal age and the morphokinetic parameters and cleavage pattern of embryos. Methods: The morphokinetics of embryos derived from women < 30, 30-35, 36-40, and > 40 years of age were compared retrospectively in terms of time of second polar body extrusion, time of pronuclei appearance, time of pronuclei fading, and time of two to eight discrete cells (t2-t8). Furthermore, abnormal cleavage patterns such as uneven blastomeres at the two-cell stage, cell fusion (Fu), and trichotomous mitoses (TM) were assessed. Results: Only t5 occurred later in women aged 36-40 and > 40 years when compared with those aged < 30 and 30-35 years (p< 0.001). Other morphokinetic timing parameters, as well the presence of uneven blastomeres, were comparable between the groups (p> 0.05). However, Fu and TM were more common in women aged > 40 years than in younger women (p< 0.001). Conclusion: Maternal age was correlated with the cleavage pattern of embryos. Therefore, evaluating embryo morphokinetics may contribute to optimal embryo selection, thereby increasing fertility in patients with advanced maternal age.
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Faramarzi, Azita,Seifi, Behjat,Sadeghipour, Hamid Reza,Shabanzadeh, Alireza,Ebrahimpoor, Mitra The Korean Society for Reproductive Medicine 2012 Clinical and Experimental Reproductive Medicine Vol.39 No.2
Objective: Sterilization (tubal sterilization and vasectomy) is a widely applied contraceptive method worldwide. Although most studies have described sterilization as a safe method, there are reports of tubal ligation (TL) and vasectomy complications. The aim of this study was to evaluate the effects of TL and vasectomy on the serum oxidative stress, specifically prooxidant-antioxidant balance (PAB) and malondialdehyde (MDA) levels, over time. Methods: Male and female rats were classified into vasectomy, sham-vasectomy, TL, and sham-TL groups, respectively. The PAB and MDA levels were measured on days 15 and 45 and months 3 and 6 after the intervention. For female rats, blood sampling was performed during the diestrous phase and estradiol and progesterone were also measured. Results: Serum PAB and MDA increased after TL (p<0.05). Vasectomy increased serum MDA remarkably after 45 days, 3 months, and 6 months (p<0.05). After vasectomy, serum PAB also increased although not significantly. Serum estradiol and progesterone decreased remarkably in the TL group compared to the sham group (p<0.05). Conclusion: Bilateral TL and vasectomy both increase the serum oxidative stress; however the imbalance after TL was very noticeable. As for the TL, the reduction of serum estrogen levels can be involved in this imbalance. Complications followed by TL or vasectomy could be due to increased levels of oxidants. Thus, prescribing antioxidants during and or after surgery may be a solution.
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Masumeh Faramarzi,Zahra Goharfar,Reza Pourabbas,Atabak Kashefimehr,Adileh Shirmohmmadi 대한구강악안면외과학회 2015 대한구강악안면외과학회지 Vol.41 No.4
Objectives: The purpose of this study was to compare the microbial and clinical effects of mechanical debridement (MD) alone or in combination with the application of enamel matrix derivative (EMD) and sustained-release micro-spherical minocycline (MSM) for treatment of peri-implant mucosal inflammation (PIMI). Materials and Methods: Subjects with at least one implant with PIMI were included and divided into control and two different test groups. In all three groups, MD was performed. In the MSM group, following MD, MSM was placed subgingivally around the implants. In the EMD group, after MD, EMD was placed in the sulcus around the implants. Sampling of peri-implant crevicular fluid for microbial analysis with real-time polymerase chain reaction and recording of probing depth (PD) and bleeding on probing (BOP) were performed prior to as well as two weeks and three months after treatment. Median values and interquartile range were estimated for each variable during the various assessment intervals of the study. Results: In all groups, at two weeks and three months, the counts of Porphyromonas gingivalis decreased significantly compared to baseline. Levels of P. gingivalis were significantly reduced in MSM (P<0.001) and EMD (P=0.026) groups compared to the control group. Also, clinical parameters improved significantly at two weeks and three months. Reduction of PD was significant in MSM (P<0.001) and EMD (P<0.001) groups. The decrease in BOP in the MSM, EMD, and control groups was 60%, 50%, and 20%, respectively. Conclusion: The use of MSM and EMD can be an adjunctive treatment for management of PIMI and improves clinical parameters and reduces P. gingivalis burden three months after treatment.
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Babak Faramarzi,An Nguyen,Fanglong Dong 대한수의학회 2018 Journal of Veterinary Science Vol.19 No.4
Appropriate hoof preparation and symmetry are linked to the well-being of the horse. Previous studies have shown the efficacy of pressure plates (PPs) in delivering objective biomechanical analysis. We aimed to assess the effect of hoof trimming on hoof biomechanics using a PP. Nine clinically sound Arabian horses were walked across a PP while foot strike was recorded by a digital camera. Kinetic and kinematic parameters were recorded before and after trimming. Changes were considered significant when p < 0.05. Vertical force (p = 0.026) and contact pressure (p = 0.006) increased after trimming. Stance-phase duration (p = 0.006), swing-phase duration (p = 0.023), and gait-cycle duration (p = 0.007) decreased significantly post-trimming. The observed changes in kinetic and kinematic parameters were related to hoof trimming. The reported results underline the importance of farriery practice and its effect on hoof biomechanics, which should be considered by both farriers and veterinarians.
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THE EFFECT OF LOYALTY PROGRAM INTRODUCTION ON STOCK RETURNS
Ashkan Faramarzi,Mehdi Nezami 글로벌지식마케팅경영학회 2018 Global Marketing Conference Vol.2018 No.07
Despite significant research and progress in examining the effects of loyalty programs on consumer behavior and firm performance, it is still unclear the firm value implications of these programs. The main goal of this article is to investigate whether announcements related to the loyalty program introduction affect firm value. In addition, the current research examines the moderating role of program, firm, and market factors in order to present a complete picture. The authors test the hypotheses empirically by conducting an event study of 134 announcements which cover a set of firms in the United States in five industries for 17 years from 2000 to 2016. We find that on average, the introduction of a loyalty program is positively related to firm value. Findings of this study will help managers understand how and under what conditions, they should introduce a loyalty program in order to affect firm value positively.
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Reza Faramarzi Hafez,Bahram Heidari,Zeynab Shahabzadeh,Bahram. Heidari 한국작물학회 2013 Journal of crop science and biotechnology Vol.16 No.4
As a medicinal plant, the importance of evening primrose (Oenothera biennis L.) is due to its unsaturated fatty acids in the seedsand roots, and also oenotherine and comfarol in the leaves. Low germination and difficulties in seed production are the main problemsencountered with growing this plant in the field. As an alternative approach, an in vitro experiment was set up for the evaluationof evening primrose production via direct and indirect regeneration of the cultivars NC-1 and VNK. For callogenesis and directregeneration, the explants from the apical bud and petiole were cultured on MS medium supplemented with 0.25, 0.75, and 1.25 mgL-1 of both BAP and Kinetin (KIN). Indirect regeneration was performed by placing apical buds, petioles, and leaf explants on MSmedium supplemented with 0.5 and 1 mg L-1 2,4-D and 0.5, 1, and 1.25 mg L-1 of both BAP and KIN. The highest shoot inductionfrom direct regeneration was obtained with apical bud explants of VNK treated with 0.75 mg L-1 BAP. The highest callus weight(3.17 g) obtained from indirect regeneration was with petiole explants treated with 1 mg L-1 2, 4-D and 1 mg L-1 BAP in VNK cultivars. The highest number of torpedo embryogenic clusters (23.8) was obtained from the VNK petiole explants treated with 0.5 mg L-12, 4-D and 1.25 mg L-1 BAP. BAP had higher positive effects on in vitro production of evening primrose than KIN in both direct andindirect regeneration. In general, results indicated that VNK was more potent for regeneration than NC-1 and concentrations of 0.75mg L-1 BAP for direct and 0.5 mg L-1 2, 4-D and 1.25 mg L-1of BAP for indirect regeneration had a higher efficiency for increasing invitro production of evening primrose
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Abdolali Faramarzi Plangar,Akbar Anaeigoudari,Abolfazl Khajavi Rad,Mohammad Naser Shafei 대한약침학회 2019 Journal of pharmacopuncture Vol.22 No.2
Objectives: Angiotensin II (AngII), a major product of renin-angiotensin system (RAS) has important role in induction of hypertension and antihypertensive effect of several medicinal plant was mediated by effect on this agent. Therefore, this study examined the possible effect of hydroalcoholic extract of Crocus sativus (C. sativus) on hypertension induced by AngII. Methods: Six groups (n = 6) of rats were used as follow:1) Control, 2) AngII (300 ng/kg), 3) Losartan (Los, 10 mg/kg) + AngII and 4-6) C. sativus extract (10, 20 & 40 mg/kg,) + AngII. The femoral artery and vein were cannulated for recording cardiovascular parameters and drugs administration, respectively. All drugs were injected intravenously (i.v). Los and all doses of C. sativus injected 10 min before AngII. Systolic blood pressure (SBP), mean arterial blood pressure (MAP) and heart rate (HR) were recorded throughout the experiment and those peak changes (Δ) were calcu-ated and compared to control and AngII. Results: AngII significantly increased ∆MAP, ∆SBP and ∆HR than control (P < 0. 01 to P < 0.001) and these increments were significantly attenuated by Los. All doses of C. sativus significantly reduced peak ΔMAP, ΔSBP, and ΔHR than AngII group (P < 0. 05 to P < 0.001). In addition, peak ΔMAP, ΔSBP in doses 10 and 20 were significant than Los + AngII group (P<0.05 to P< 0.01) but in dose 40 only MAP was significant (P<0.05). Peak ΔHR in all doses of C sativus was not significant than Los+ AngII. Conclusion: Regarding the improving effect of the C. sativus extract on AngII induced hypertension, it seems that this ameliorating effect partly mediated through inhibition of RAS.
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Hafez, Reza Faramarzi,Shahabzadeh, Zeynab,Heidari, Bahram,Ghadimzadeh, Morteza 한국작물학회 2013 Journal of crop science and biotechnology Vol.16 No.4
As a medicinal plant, the importance of evening primrose (Oenothera biennis L.) is due to its unsaturated fatty acids in the seeds and roots, and also oenotherine and comfarol in the leaves. Low germination and difficulties in seed production are the main problems encountered with growing this plant in the field. As an alternative approach, an in vitro experiment was set up for the evaluation of evening primrose production via direct and indirect regeneration of the cultivars NC-1 and VNK. For callogenesis and direct regeneration, the explants from the apical bud and petiole were cultured on MS medium supplemented with 0.25, 0.75, and $1.25mg\;L^{-1}$ of both BAP and Kinetin (KIN). Indirect regeneration was performed by placing apical buds, petioles, and leaf explants on MS medium supplemented with 0.5 and $1mg\;L^{-1}$ 2,4-D and 0.5, 1, and $1.25mg\;L^{-1}$ of both BAP and KIN. The highest shoot induction from direct regeneration was obtained with apical bud explants of VNK treated with $0.75mg\;L^{-1}$ BAP. The highest callus weight (3.17 g) obtained from indirect regeneration was with petiole explants treated with $1mg\;L^{-1}$ 2, 4-D and $1mg\;L^{-1}$ BAP in VNK cultivars. The highest number of torpedo embryogenic clusters (23.8) was obtained from the VNK petiole explants treated with $0.5mg\;L^{-1}$ 2, 4-D and $1.25mg\;L^{-1}$ BAP. BAP had higher positive effects on in vitro production of evening primrose than KIN in both direct and indirect regeneration. In general, results indicated that VNK was more potent for regeneration than NC-1 and concentrations of $0.75mg\;L^{-1}$ BAP for direct and $0.5mg\;L^{-1}$ 2, 4-D and $1.25mg\;L^{-1}$of BAP for indirect regeneration had a higher efficiency for increasing in vitro production of evening primrose.
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Plangar, Abdolali Faramarzi,Anaeigoudari, Akbar,KhajaviRad, Abolfazl,Shafei, Mohammad Naser KOREAN PHARMACOPUNCTURE INSTITUTE 2019 Journal of pharmacopuncture Vol.22 No.2
Objectives: Angiotensin II (AngII), a major product of renin-angiotensin system (RAS) has important role in induction of hypertension and antihypertensive effect of several medicinal plant was mediated by effect on this agent. Therefore, this study examined the possible effect of hydroalcoholic extract of Crocus sativus (C. sativus) on hypertension induced by AngII. Methods: Six groups (n = 6) of rats were used as follow: 1) Control, 2) AngII (300 ng/kg), 3) Losartan (Los, 10 mg/kg) + AngII and 4-6) C. sativus extract (10, 20 & 40 mg/kg,) + AngII. The femoral artery and vein were cannulated for recording cardiovascular parameters and drugs administration, respectively. All drugs were injected intravenously (i.v). Los and all doses of C. sativus injected 10 min before AngII. Systolic blood pressure (SBP), mean arterial blood pressure (MAP) and heart rate (HR) were recorded throughout the experiment and those peak changes (${\Delta}$) were calculated and compared to control and AngII. Results: AngII significantly increased ${\Delta}MAP$, ${\Delta}SBP$ and ${\Delta}HR$ than control (P < 0. 01 to P < 0.001) and these increments were significantly attenuated by Los. All doses of C. sativus significantly reduced peak ${\Delta}MAP$, ${\Delta}SBP$, and ${\Delta}HR$ than AngII group (P < 0. 05 to P < 0.001). In addition, peak ${\Delta}MAP$, ${\Delta}SBP$ in doses 10 and 20 were significant than Los + AngII group (P<0.05 to P< 0.01) but in dose 40 only MAP was significant (P<0.05). Peak ${\Delta}HR$ in all doses of C sativus was not significant than Los+ AngII. Conclusion: Regarding the improving effect of the C. sativus extract on AngII induced hypertension, it seems that this ameliorating effect partly mediated through inhibition of RAS.
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