An empirical study of blended teaching model based on SPOC— Take the course "Modern Educational Technology" as an example

Liu-wen DING,Shi-mei JIN ASCONS 2022 IJASC Vol.4 No.1

Background: In order to fight the epidemic, the Ministry of Education, PRC has put forward a work plan of "no suspension of classes", which promotes the sharing of high-quality online teaching resources through online education, promotes the "classroom revolution" by changing teaching and learning methods, and provides a learning platform with network technology, thus promoting the development of mixed teaching. Statistical analysis: In order to adapt to the development trend of contemporary educational information and fully consider the principal position of students. Finding: a blended teaching mode based on SPOC which is suitable for the courses combining theory and practice is formulated. Taking the course of "Modern Educational Technology" as an example, the blended teaching is studied in detail. Applications: in order to provide reference for future blended teaching research.

N-doped porous carbons with increased yield and hierarchical pore structures for supercapacitors derived from an N-containing phenyl-riched copolymer

Ding-Ming Xue,Shi-Chao Qi,Xin Liu,Yu-Xia Li,Xiao-Qin Liu,Lin-Bing Sun 한국공업화학회 2019 Journal of Industrial and Engineering Chemistry Vol.80 No.-

N-doped porous carbon-based materials (NPCMs) with hierarchical pore structures have beenconsidered to be a suitable alternative to meet the ever-increasing demands for supercapacitors;however, the universally low yield of the NPCMs has restricted their practical applications. Herein, aseries of NPCMs with hierarchical pore structures are synthesized with significantly increased yieldsthrough the carbonization of the copolymer made from 2,4,6-tris(chloromethyl)mesitylene and pphenylenediamine. The development of the hierarchical pore structures and the N content of the NPCMsshow opposite dependences on the increasing carbonization temperature. The NPCM exhibits the bestcapacitive ability only if the sufficiently developed hierarchical structures and moderate N content areachieved simultaneously. Therefore, NPCM-600 that is carbonized at 600 C with an excellent yield of53.6% (wt.), large specific surface area of 1778 m2 g 1, and N content of 4.13% (wt.) yields an ideal specificcapacitance of 298 F g 1 at the current density of 1 A g 1 and a perfect cycling stability of the capacitanceafter 10,000 cycles at 10 A g 1. The yield of the NPCM-600 is considerably higher than those for manyother recently reported NPCMs. NPCM-600 also shows better capacitance than those of the otherreported NPCMs, such as NOPC-bis-CN-3 (167 F g 1) and CHCPB-K-600 (260 F g 1).

Analysis and Optimization of Asymmetric Hybrid Permanent Magnet Motor for Electric Vehicle

Liu Kaiwen,Shi Liwei,Liu Zhengwei,Wang Wenqiang,Ding Hongshan 대한전기학회 2023 Journal of Electrical Engineering & Technology Vol.18 No.5

An asymmetric hybrid permanent magnet motor (AHPMM) is proposed for the traditional permanent magnet motor (TPMM) with a large amount of rare earth materials and high cogging torque. The equivalent magnetic circuit model of the motor is established and the factors affecting the fluctuation of cogging torque are analyzed. With the objective of reducing the torque ripple and cogging torque of the AHPMM, the motor is parametrically modeled and analyzed, and multi-objective hierarchical optimization of the motor parameters is carried out using a hybrid algorithm combining the response surface algorithm and the single scan method, which ultimately determines the optimal combination of motor dimensional parameters. The electromagnetic performance of the AHPMM compared to the TPMM is analyzed using the finite element method. The results show that, without any decrease in output torque, the use of rare-earth materials is reduced by 18.5%, the cogging torque and the total harmonic distortion of the No-load back EMF waveform are reduced by 0.78 Nm and 4.7% respectively compared to the TPMM. Finally, a prototype motor is manufactured and the validity of the theoretical analysis and design of the AHPMM is verified through experiments.

Combinatorial development of bulk metallic glasses

Ding, Shiyan,Liu, Yanhui,Li, Yanglin,Liu, Ze,Sohn, Sungwoo,Walker, Fred J.,Schroers, Jan Nature Publishing Group, a division of Macmillan P 2014 NATURE MATERIALS Vol.13 No.5

The identification of multicomponent alloys out of a vast compositional space is a daunting task, especially for bulk metallic glasses composed of three or more elements. Despite an increasing theoretical understanding of glass formation, bulk metallic glasses are predominantly developed through a sequential and time-consuming trial-and-error approach. Even for binary systems, accurate quantum mechanical approaches are still many orders of magnitude away from being able to simulate the relatively slow kinetics of glass formation. Here, we present a high-throughput strategy where ∼3,000 alloy compositions are fabricated simultaneously and characterized for thermoplastic formability through parallel blow forming. Using this approach, we identified the composition with the highest thermoplastic formability in the glass-forming system Mg–Cu–Y. The method provides a versatile toolbox for unveiling complex correlations of material properties and glass formation, and should facilitate a drastic increase in the discovery rate of metallic glasses.

Key Application Technologies of High Efficiency Power Quality Control Systems

Ding-Guo Liu,Zhi-kang Shuai,Chun-ming Tu,Ying Cheng,An Luo 전력전자학회 2013 JOURNAL OF POWER ELECTRONICS Vol.13 No.3

Large capacity reactive power compensation and harmonic control in the low-voltage grid of an enterprise, are important technical means to improve power quality and reduce power loss. In this paper, the principle of an efficient power quality controller is analyzed. Then, key application technologies of the HPQC which would influence the performances of the HPQC are studied. Based on an analysis of the harmonic shunt problem, a frequency dividing control strategy of the HPQC continuous subsystem is proposed. A parameter design method of the HPQC discrete subsystem and its installation method are also proposed to ensure the system compensation effect. HPQC systems have been designed for a copper foil plant. The effectiveness of this paper has been verified by the simulation and application results.

Enhanced performance of LSCF cathode through surface modification

Liu, M.,Ding, D.,Blinn, K.,Li, X.,Nie, L.,Liu, M. Pergamon Press ; Elsevier Science Ltd 2012 International journal of hydrogen energy Vol.37 No.10

Mixed ionic-electronic conductors in the family of La<SUB>x</SUB>Sr<SUB>1-x</SUB>Co<SUB>y</SUB>Fe<SUB>1-y</SUB>O<SUB>3-δ</SUB> (LSCF) have been widely studied as cathode materials for solid oxide fuel cells (SOFCs). However, the long-term stability and the limited surface catalytic activity are still a concern. Here we report a new catalyst La<SUB>0.4875</SUB>Ca<SUB>0.0125</SUB>Ce<SUB>0.5</SUB>O<SUB>2-δ</SUB> (LCC), which can significantly enhance the performance and stability of LSCF cathodes when applied as a thin-film coating on LSCF surface. For example, with 5 μL 0.25 mol L<SUP>-1</SUP> LCC solution infiltrated into LSCF cathode, the cathodic polarization resistance was reduced by ∼60% (to ∼0.076 Ω cm<SUP>2</SUP>) at 750 <SUP>o</SUP>C, leading to a peak power density of ∼1.25 W/cm<SUP>2</SUP>, which is ∼18% higher than that for the unmodified LSCF cathode in an anode-supported cell. In addition, stable power output was observed for over 500 h operation at 750 <SUP>o</SUP>C under a constant voltage of 0.7 V.

Tissues Expression, Polymorphisms Identification of FcRn Gene and Its Relationship with Serum Classical Swine Fever Virus Antibody Level in Pigs

Liu, Yang,Wang, Chonglong,Liu, Zhengzhu,Xu, Jingen,Fu, Weixuan,Wang, Wenwen,Ding, Xiangdong,Liu, Jianfeng,Zhang, Qin Asian Australasian Association of Animal Productio 2012 Animal Bioscience Vol.25 No.8

Neonatal Fc receptor (FcRn) gene encodes a receptor that binds the Fc region of monomeric immunoglobulin G (IgG) and is responsible for IgG transport and stabilization. In this report, the 8,900 bp porcine FcRn genomic DNA structure was identified and putative FcRn protein included 356 amino acids. Alignment and phylogenetic analysis of the porcine FcRn amino acid sequences with their homologies of other species showed high identity. Tissues expression of FcRn mRNA was detected by real time quantitative polymerase chain reaction (Q-PCR), the results revealed FcRn expressed widely in ten analyzed tissues. One single nucleotide polymorphism (SNP) (HQ026019:g.8526 C>T) in exon6 region of porcine FcRn gene was demonstrated by DNA sequencing analysis. A further analysis of SNP genotypes associated with serum Classical Swine Fever Virus antibody (anti-CSFV) concentration was performed in three pig populations including Large White, Landrace and Songliao Black pig (a Chinese indigenous breed). Our results of statistical analysis showed that the SNP had a highly significant association with the level of anti-CSFV antibody (At d 20; At d 35) in serum (p = 0.008; p = 0.0001). Investigation of expression and polymorphisms of the porcine FcRn gene will help us in further understanding the molecular basis of the antibody regulation pathway in the porcine immune response. All these results indicate that FcRn gene might be regarded as a molecular marker for genetic selection of anti-CSFV antibody level in pig disease resistance breeding programmes.

Tissues Expression, Polymorphisms of IFN Regulatory Factor 6 (IRF6) Gene and Their Associated with Immune Traits in Three Pig Populations

Liu, Yang,Xu, Jingeng,Fu, Weixuan,Weng, Ziqing,Niu, Xiaoyan,Liu, Jianfeng,Ding, Xiangdong,Zhang, Qin Asian Australasian Association of Animal Productio 2012 Animal Bioscience Vol.25 No.2

Interferon regulatory factor 6 (IRF6) gene is a member of the IRF-family, and plays functionally diverse roles in the regulation of the immune system. In this report, the 13,720 bp porcine IRF6 genomic DNA structure was firstly identified with a putative IRF6 protein of 467 amino acids. Alignment and phylogenetic analysis of the porcine IRF6 amino acid sequences with their homologies to other species showed high identity (over 96%). Tissues expression of IRF6 mRNA was observed by RT-PCR, the results revealed IRF6 expressed widely in eight tissues. One SNP (HQ026023:1383 G>C) in exon7 and two SNPs (HQ026023:130 G>A; 232 C>T) in the 5′ promoter region of porcine IRF6 gene were demonstrated by DNA sequencing analysis. A further analysis of SNP genotypes associated with immune traits including IFN-${\gamma}$ and IL10 concentrations in serum was carried out in three pig populations including Large White, Landraces and Songliao Black pig (a Chinese indigenous breed). The results showed that the SNP (HQ026023:1383 G>C) was significantly associated with the level of IFN-${\gamma}$ (d 20) in serum (p = 0.038) and the ratio of IFN-${\gamma}$ to IL10 (d 20) in serum (p = 0.041); The other two SNPs (HQ026023:130 G>A; 232 C>T) were highly significantly associated with IL10 level in serum both at the day 20 (p = 0.005; p = 0.001) and the day 35 (p = 0.004; p = 0.006). Identification of the porcine IRF6 gene will help our further understanding of the molecular basis of the IFN regulation pathway in the porcine immune response. All these results should indicate that the IRF6 gene can be regarded as a molecular marker associated with the IL10 level in serum and used for genetic selection in the pig breeding.

Genetic Variability of mtDNA Sequences in Chinese Native Chicken Breeds

Liu, Z.G.,Lei, C.Z.,Luo, J.,Ding, C.,Chen, G.H.,Chang, H.,Wang, K.H.,Liu, X.X.,Zhang, X.Y.,Xiao, X.J.,Wu, S.L. Asian Australasian Association of Animal Productio 2004 Animal Bioscience Vol.17 No.7

The variability of mtDNA hypervariable segment I (HVS I) sequences was investigated in a total of 48 birds belonging to 12 Chinese native chicken breeds. Sixteen haplotypes were identified from 35 polymorphic nucleotide sites which accounted for 6.4% of a sequenced 544 bp fragment. Diversity analysis of the haplotypes showed that Tibetan, Langshan and Henan cockfight chicken had only one haplotype, while ancient haplotypes existed in Taihe silky and Chahua chicken. Phylogenetic analysis of the haplotypes suggested that Chinese native chicken breeds shared 5 maternal lineages and some breeds would share the same maternal lineage, regardless of their external features and ecological types. Both divergent and phylogenetic analysis of the haplotypes indicated the close genetic relationships between the Chinese native chicken breeds and G. g. gallus and G. g. spadiceus from different areas, which implied that G. g. gallus and G. g. spadiceus were the original ancestors of the Chinese native chicken breeds.

Emerging Roles of Krüppel-Like Factor 4 in Cancer and Cancer Stem Cells

Ding, Bo,Liu, Ping,Liu, Wen,Sun, Ping,Wang, Chun-Ling Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.9

Cancer stem cells (CSCs) are rare subpopulations within tumors which are recognized as culprits in cancer recurrence, drug resistance and metastasis. However, the molecular mechanisms of how CSCs are regulated remain elusive. Kr$\ddot{u}$ppel-like factors (KLFs) are evolutionarily conserved zinc finger-containing transcription factors with diverse functions in cell differentiation, proliferation, embryogenesis and pluripotency. Recent progress has highlighted the significance of KLFs, especially KLF4, in cancer and CSCs. Therefore, for better therapeutics of cancer disease, it is crucial to develop a deeper understanding of the mechanisms of how KLF4 regulate CSC functions. Herein we summarized the current understanding of the transcriptional regulation of K LF4 in CSCs, and discussed the functional implications of targeting CSCs for potential cancer therapeutics.