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        • SCIESCOPUSKCI등재

          Helicobader pylori Infection: Epidemiology, Pathophysiology, and Therapy

          Crespo,,Antonio,Suh,,Byungse The Pharmaceutical Society of Korea 2001 Archives of Pharmacal Research Vol.24 No.6

          Helicobacter pylori is one of the most commonly encountered human pathogens. It has been shown to be closely associated with peptic ulcer disease (PUD), gastric adenocarcinoma, and the gastric mucosa-associated lymphoid tissue (MALT) that may lead to gastric lymphoma. The current diagnostic methods include histology, microbiological culture, classic serology unease activity detection, polymerase chain reaction (PCR) and stool antigen detection. Its treatment modality options are multiple; however, a triple regimen consisting of a proton pump inhibitor (PPI), and two antibiotics for 10 to 14 days is preferred. Drug resistance is a growing problem in this organism and new therapeutic options are currently limited .

        • SCOPUSKCI등재

          Multiple Chemical Sensitivity in Chemical Laboratory Workers

          Perez-Crespo,,Juan,Lobato-Canon,,Rafael,Solanes-Puchol,,Angel Occupational Safety and Health Research Institute 2018 Safety and health at work Vol.9 No.4

          Background: Multiple Chemical Sensitivity (MCS) is an acquired disease which etiology remains unknown. It is characterized by the development of sensitivity to certain chemical products. Most of the hypotheses formulated to explain the syndrome associate it to a previous exposition to some kind of volatile chemical. University researchers in chemical laboratories suffer a phenomenon of multi-exposition to chemical agents at low concentration during long periods of time although in an irregular form. Many of these chemical agents have similar properties to those suspicious of causing MCS. This article studies the prevalence of MCS in laboratory researchers. Methods: The study group is university researchers in chemical laboratories. The control group was obtained from administrative personnel who work in the same universities and therefore, are not exposed to chemical products from the laboratories, but have the same exposition to the rest of environmental polluting agents from the area and from the buildings of the university. In this study, it is used the Quick Environmental Exposure and Sensitivity Inventory (QEESI) (sensitivity of 92%/specificity of 95%). Results: The results showed that the prevalence of MCS for the university researchers is not related to exposition by inhalation to multiple chemical agents, at low concentration. Conclusions: The results disagree with one of the main etiological hypotheses of MCS, which is based on the existence of hypersensitive people, who presents a response after prolonged expositions to very low concentrations during a long period of time.

        • KCI등재SCOPUS

          Multiple Chemical Sensitivity in Chemical Laboratory Workers

          Juan,Pérez-Crespo,Rafael,Lobato-Cañón,Ángel,Solanes-Puchol 한국산업안전보건공단 산업안전보건연구원 2018 Safety and health at work Vol.9 No.4

          Background: Multiple Chemical Sensitivity (MCS) is an acquired disease which etiology remains unknown. It is characterized by the development of sensitivity to certain chemical products. Most of the hypotheses formulated to explain the syndrome associate it to a previous exposition to some kind of volatile chemical. University researchers in chemical laboratories suffer a phenomenon of multiexposition to chemical agents at low concentration during long periods of time although in an irregular form. Many of these chemical agents have similar properties to those suspicious of causing MCS. This article studies the prevalence of MCS in laboratory researchers. Methods: The study group is university researchers in chemical laboratories. The control group was obtained from administrative personnel who work in the same universities and therefore, are not exposed to chemical products from the laboratories, but have the same exposition to the rest of environmental polluting agents from the area and from the buildings of the university. In this study, it is used the Quick Environmental Exposure and Sensitivity Inventory (QEESI) (sensitivity of 92%/specificity of 95%). Results: The results showed that the prevalence of MCS for the university researchers is not related to exposition by inhalation to multiple chemical agents, at low concentration. Conclusions: The results disagree with one of the main etiological hypotheses of MCS, which is based on the existence of hypersensitive people, who presents a response after prolonged expositions to very low concentrations during a long period of time.

        • KCI등재SSCISCOPUS

          Long-Term Grey Matter Changes in First Episode Psychosis: A Systematic Review

          Ruth,Gallardo-Ruiz,Benedicto,Crespo-Facorro,Esther,Setié,n-Suero,Diana,Tordesillas-Gutierrez 대한신경정신의학회 2019 PSYCHIATRY INVESTIGATION Vol.16 No.5

          '스콜라' 이용 시 소속기관이 구독 중이 아닌 경우, 오후 4시부터 익일 오전 7시까지 원문보기가 가능합니다.

          Objective: To determine possible progressive changes of the grey matter at the first stages of the schizophrenia spectrum disorders, and to determine what regions are involved in these changes. Methods: We searched the literature concerning studies on longitudinal changes in grey matter in first-episode psychosis using magnetic resonance imaging, especially studies with an interval between scans of more than a year. Only articles published before 2018 were searched. We selected 19 magnetic resonance imaging longitudinal studies that used different neuroimaging analysis techniques to study changes in cerebral grey matter in a group of patients with a first episode of psychosis. Results: Patients with first episode of psychosis showed a decrease over time in cortical grey matter compared with a group of control subjects in frontal, temporal (specifically in superior regions), parietal, and subcortical regions. In addition to the above, studies indicate that patients showed a grey matter decrease in cerebellum and lateral ventricles volume. Conclusion: The results suggest a decrease in grey matter in the years after the first episode of psychosis. Furthermore, the results of the studies showed consistency, regardless of the methods used in their analyses, as well as the time intervals between image collections.

        • SCIESCOPUSKCI등재

          Reproductive development and seasonal activity of two Korean native Coprini species (Coleoptera: Scarabaeidae)

          Bang,,Hea-Son,Crespo,,Carmen,Huerta,Na,,Young-Eun,Han,,Min-Su,Lee,,Joon-Ho 한국응용곤충학회 2008 Journal of Asia-Pacific Entomology Vol. No.

          Seasonal activity of the native dung beetles, Copris ochus (Motschulsky) and Copris tripartitus Waterhouse, was studied in Jeju Island, Korea. Reproductive condition and breeding cycles of adult females were determined using physiological age-grading techniques to assess the proportions of newly emerged, nulliparous and parous beetles, and those resorbing oocytes. C. ochus appears to be univoltine. Its main period of adult emergence occurs in summer rather than in spring (March-May), as was previously thought. The female population consisted of the complete range of reproductive age classes in August-September. C. tripartitus also appears to be univoltine. However, this species has two adult activity periods: a peak activity in spring when most oviposition occurs, and another in autumn when the new generation emerges. With the onset of winter, C. tripartitus adults cease reproductive development and females over winter in a nulliparous stage.

        • KCI등재SCOPUS

          Reproductive development and seasonal activity of two Korean native Coprini species (Coleoptera: Scarabaeidae)

          Hea-Son,Bang,Carmen,Huerta,Crespo,Young-Eun,Na,Min-Su,Han,이준호 한국응용곤충학회 2008 Journal of Asia-Pacific Entomology Vol.11 No.4

          Seasonal activity of the native dung beetles, Copris ochus (Motschulsky) and Copris tripartitus Waterhouse, was studied in Jeju Island, Korea. Reproductive condition and breeding cycles of adult females were determined using physiological age-grading techniques to assess the proportions of newly emerged, nulliparous and parous beetles, and those resorbing oocytes. C. ochus appears to be univoltine. Its main period of adult emergence occurs in summer rather than in spring (March–May), as was previously thought. The female population consisted of the complete range of reproductive age classes in August– September. C. tripartitus also appears to be univoltine. However, this species has two adult activity periods: a peak activity in spring when most oviposition occurs, and another in autumn when the new generation emerges. With the onset of winter, C. tripartitus adults cease reproductive development and females over winter in a nulliparous stage.

        • SCIESCOPUSKCI등재

          QoSNC: A Novel Approach to QoS-Based Network Coding for Fixed Networks

          Salavati,,Amir,Hesam,Khalaj,,Babak,Hossein,Crespo,,Pedro,M.,Aref,,Mohammad,Reza The Korean Institute of Communications and Informa 2010 Journal of communications and networks Vol.12 No.1

          In this paper, we present a decentralized algorithm to find minimum cost quality of service (QoS) flow subgraphs in network coded multicast schemes. The main objective is to find minimum cost subgraphs that also satisfy user-specified QoS constraints, specifically with respect to rate and delay demands. We consider networks with multiple multicast sessions. Although earlier network coding algorithms in this area have demonstrated performance improvements in terms of QoS parameters, the proposed QoS network coding approach provides a framework that guarantees QoS constraints are actually met over the network.

        • Flexible Real-time Embedded Architecture for Advanced Service Robots

          David,Ramada,Carlos,Dominguez,Houcine,Hassan,Alfons,Crespo 보안공학연구지원센터 2008 International Journal of Smart Home Vol.2 No.4

          In most advanced real-time control applications such as service robots, the tasks have different criticality, flexible timing constraints and variable execution time. For instance, autonomous service robots perform their activities in dynamic environments, share resources and have to cooperate to fulfill their objectives. These changing environmental conditions produce a variability of the system load. Firstly, the computational requirements of recognition tasks are variable and dependent on the number of objects perceived in scenes. Secondly, the application processes are executed at different frequencies with varying periods and deadlines that are dependent on robot speeds. To tackle these aspects a flexible real-time architecture is implemented in rt-linux in this paper. Moreover, the architecture permits to extract the slack time, enabled in the system due to load variability, and to invest it in improving the communication performances of the robots. Experimental evaluations of the architecture have been carried out with real autonomous robots.

        • Electronic excitations in molecular solids: bridging theory and experiment

          Skelton,,Jonathan,M.,Lora,da,Silva,,E.,Crespo-Otero,,Rachel,Hatcher,,Lauren,E.,Raithby,,Paul,R.,Parker,,Stephen,C.,Walsh,,Aron The Royal Society of Chemistry 2015 Faraday discussions Vol.177 No.-

          <P>As the spatial and temporal resolution accessible to experiment and theory converge, computational chemistry is an increasingly powerful tool for modelling and interpreting spectroscopic data. However, the study of molecular processes, in particular those related to electronic excitations (<I>e.g.</I> photochemistry), frequently pushes quantum-chemical techniques to their limit. The disparity in the level of theory accessible to periodic and molecular calculations presents a significant challenge when modelling molecular crystals, since accurate calculations require a high level of theory to describe the molecular species, but must also take into account the influence of the crystalline environment on their properties. In this article, we briefly review the different classes of quantum-chemical techniques, and present an overview of methods that account for environmental influences with varying levels of approximation. Using a combination of solid-state and molecular calculations, we quantitatively evaluate the performance of implicit-solvent models for the [Ni(Et<SUB>4</SUB>dien)(η<SUP>2</SUP>-O,ON)(η<SUP>1</SUP>-NO<SUB>2</SUB>)] linkage-isomer system as a test case. We focus particularly on the accurate reproduction of the energetics of the isomerisation, and on predicting spectroscopic properties to compare with experimental results. This work illustrates how the synergy between periodic and molecular calculations can be exploited for the study of molecular crystals, and forms a basis for the investigation of more challenging phenomena, such as excited-state dynamics, and for further methodological developments.</P>

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