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한진철,윤충화 明知大學校 産業技術硏究所 2005 産業技術硏究所論文集 Vol.24 No.-
RPA (Recursive Pattern Averaging) algorithm, which is an instance-based learning method, generates representative patterns from training set, and uses them to classify a test pattern by computing Euclidean distances. RPA is proven to show satisfactory performance, but it has a major disadvantage that it cannot explain the user how the classification result is obtained. This explanation capability is crucial to some domains where expert systems are employed. In order to overcome this disadvantage, we propose a rule-extracting algorithm that produces IF-THEN rules from RPA method, and a pruning algorithm by expanding conditions in IF part of rules in order to improve generalization capability.
한진철,김상귀,윤충화 명지대학교 산업기술연구소 2006 産業技術硏究所論文集 Vol.25 No.-
K-NN (k-Nearest Neighbors), which is a well-known memory-based learning algorithm, simply stores entire training patterns in memory, and uses a distance function to classify a test pattern. K-NN is proven to show satisfactory performance, but it is notorious for memory usage and lengthy computation. Various studies have been found in the literature in order to minimize memory usage and computation time, and NGE (Nested Generalized Exemplar) theory is one of them. In this paper, we propose RPA (Recursive Partition Averaging) and IRPA (Incremental RPA) which is an incremental version of RPA. RPA partitions the entire pattern space recursively, and generates representatives from each partition. Also, due to the fact that RPA is prone to produce excessive number of partitions as the number of features in a pattern increases, we present IRPA which reduces the number of representative patterns by processing the training set in an incremental manner. Our proposed methods have been successfully shown to exhibit comparable performance to k-NN with a lot less number of patterns and better result than EACH system which implements the NGE theory.
金翰華,盧鏞泰,鄭英和,池永得 최신의학사 1977 最新醫學 Vol.20 No.11
The authors observed the ultrastructures of the keratinocytes in the epidermis of dorsal skin of the four species in the Korean amphibia: Bombina orientalis; Kaloula borealis, Rana nigromaculata and Rana rugosa. The results were as follows: 1. Amphibian epidermis consisted of 5 or 6 layers of keratinocytes and were divided into four strata: stratum germinativum (1 cell layer), stratum spinosum (1 or 2 cell layers), stratum granulosum (1 or 2 cell layers) and stratum corneum (1 or 2 cell layers) 2. Many microfilaments and secretory mucous granules developed" during cornification of the keratinocytes in the amphibian epidermis without keratohyalin granules developing in the mammalian epidermis. 3. The keratinocytes of the amphibian epidermis were mostly connected with desmosomes. Hemidesmosomes were found between the basal lamina and the basal face of the stratum germinativum and composite desmosomes between the upper face of the stratum granulosum and the basal face of the stratum corneum. The, surface keratinized cells were connected with zonula occludens in the upper portion and with modified desmosomal elements in the lower portion, 4. The keratinocytes of the amphibian epidermis were different in ultrastructure at each stratum. a. In the stratum germinativum, the keratinocytes were columnar or cuboidal in form. Many mitochondria, microfilaments and ribosomes were found in the cytoplasm. b. In the stratum spinosum, the keratinocytes were cuboidal or polygonal in form, Many microfilaments and ribosomes were found and a few granular and agranular endoplasmic reticulum and Golgi complex developed in the cytoplasm. c. In the stratum granulosum, the keratinocytes were squamous in form and the intercellular spaces well developed. Many microfilaments, ribosomes, secretory mucous granules and pigment granules were found in the cytoplasm. d. In the stratum corneum, the keratinocytes were squamous in form and were filled with microfilaments. A few vacuoles and remnants of cell organelles were seen in the cytoplasm.
천식환자에서 병발된 S 단백 결핍과 연관된 폐동맥 색전증
박정화 ( Chung Hwa Park ),윤승배 ( Seung Bae Yoon ),김대범 ( Dae Bum Kim ),이한희 ( Han Hee Lee ),김찬준 ( Chan Joon Kim ),김정호 ( Jeong Ho Kim ),고훈영 ( Hoon Young Ko ),이미정 ( Mi Jeong Lee ),이화정 ( Hwa Jeong Lee ),김승수 ( 대한천식알레르기학회 2010 천식 및 알레르기 Vol.30 No.2
Asthma is a chronic multifactorial disease with frequent exacerbations in many patients. Much effort has been made to determine prevalent factors associated with difficult- to-control asthma. Here we report the case of a 57-year-old man who was treated for asthma during the last 4 years at our pulmonology clinic. Recently, the patient experienced severe dyspnea for more than 3 months despite the addition of the leukotriene modifier, theophylline and oral cortic- osteroid. Chest CT scans revealed multifocal areas of pulmonary arterial thrombosis. Doppler ultrasonograms showed multiple deep vein thrombi. The patient was diagnosed of having protein S deficiency and was treated with low molecular weight heparin, followed by oral warfarin. Now, he has no pulmonary arterial thrombosis and has no more asthmatic attack for half a year. (Korean J Asthma Allergy Clin Immunol 2010;30:135-139)