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Park, H.J.,Lee, S.J.,Kim, S.H.,Han, J.,Bae, J.,Kim, S.J.,Park, C.G.,Chun, T. Pergamon Press 2011 Molecular immunology Vol.48 No.4
Autophagy is an important process which maintains cellular homeostasis under stressful conditions such as starvation and pathogenic invasion. Previous observations have indicated that several cytokines are important regulators of the autophagic process. Among the various cytokines, IL-10 has a unique property which functions to suppress overall immunity. However, the functional role of IL-10 during the autophagic process has not been studied. In this study, we examined the effect of IL-10 during starvation induced autophagy of murine macrophages (J774). The results clearly indicated that IL-10 and IL-10 receptor signaling inhibits autophagy induction of murine macrophage. Further experiments revealed that IL-10 activates the class I phosphatidylinositol 3-kinase (PI3K) pathway, which results in the phosphorylation of p70S6K through the activation of Akt and a mammalian target of the rapamycin complex 1 (mTORC 1). These results will advance our understanding of the physiological function of IL-10 during the autophagic process of macrophage.
Concept of Food Sensory Engineering and Its Application
Chun, J.K. 한국산업식품공학회 2002 산업 식품공학 Vol.6 No.3
A concept of food sensory evaluation on the basis of multi-layer consciousness theory of Vasubandhu with three-way branching perception logic was developed. To understand the relationship between sensory reaction and consciousness, a model of consciousness structure and flow chart of mental process was constructed with incorporation of different time units and transformation processes. Based on the analogies among five sensory system of human and computer logic, time and attention weight were included in the new sensory evaluation concept. The concept was applied to develop a new sensory evaluation method using bar code and frequency concept. The sensory questionnaire consisted of objective and subjective consciousness parameters. Using the responses of the subjects, bar codes with different intervals and thickness were generated after the calibration of the bar width by multiplying attention weight factors to the relevant consciousness layer, and it was transformed into relevant sensory curves to produce an individual sensory curve. The method was tested 12 subjects for cooked rice. Sensory barcode and curve patterns of cooked rice showed remarkable differences in their patterns among the individuals.
Privacy-preserving disjunctive normal form operations on distributed sets
Chun, J.Y.,Hong, D.,Jeong, I.R.,Lee, D.H. North-Holland [etc ; Elsevier Science Ltd 2013 Information sciences Vol.231 No.-
Privacy-preserving set operations such as set union and set intersection on distributed sets are widely used in data mining in which the preservation of privacy is of the utmost concern. In this paper, we extended privacy-preserving set operations and considered privacy-preserving disjunctive normal form (DNF) operations on distributed sets. A privacy-preserving DNF operation on distributed sets can be used to find a set S<SUB>F</SUB> satisfying S<SUB>F</SUB>=(S<SUB>1,1</SUB>@?...@?S<SUB>1,t'2</SUB>)@?...@?(S<SUB>t'1,1</SUB>@?...@?S<SUB>t'1,t'2</SUB>) without revealing any other information besides just the information which could be inferred from the DNF operations, where S<SUB>i,j</SUB>@?{A<SUB>1</SUB>,...,A<SUB>n</SUB>,A<SUB>1</SUB>@?,...,A<SUB>n</SUB>@?} and set A<SUB>k</SUB> is known only to a party P<SUB>k</SUB>. A complement set A<SUB>k</SUB>@? is defined as A<SUB>k</SUB>@?=(A<SUB>1</SUB>@?...@?A<SUB>n</SUB>)-A<SUB>k</SUB>. Using privacy-preserving DNF operations on distributed sets, it is possible to find set union, (threshold) set intersection, and a set of k-repeated elements.
곽지연,김서연,김자영,이혜연,정문정,진수현,천선우,하소현,한희진,양숙자,김지연 이화여자대학교 간호과학대학 2016 이화간호학회지 Vol.- No.50
Purpose: The purpose of this study was to identify college student's perception and practice of 'National Cancer Prevention Actions' and the factors that influence the perception and practice. Method: The participants were 310 undergraduates selected by convenience sampling at colleges in Seoul. Instrument was 2014 Survey of Perception and Practice of National Cancer Prevention Actions by National Cancer Center(2014), and has been modified for the purpose of the study. The data were analyzed by t-test, ANOVA and Scheffe test with SPSS 23.0 Windows software. Results: The most recognized action for cancer prevention in college students was "Do not smoke, also avoid smoking smoke"(96.8%) while the most unrecognized was "Get a type B hepatitis vaccination"(58.7%). The most practiced action for cancer prevention in college students was "Sexually as to safe sex"(94.8%) while the most unpracticed was "Exercise five times a week or more, for at least 30 minutes a day"(33.9%). Among general characteristics, participants' age (t=-2.015, p<.05), major (F=3.109, p<.001), and residential type (F=4.959, p<.01) were statistically significant in the recognition of Cancer Prevention Actions and major(F=3.341 p<.05) and residential type(F=3.827, p<.05) were also significant in the practice of Cancer Prevention Actions. Among health characteristics, health concern(F=3.154, p<.05) and education in cancer(t=-3.112, p<.01) showed statistically significant differences in the recognition of Cancer Prevention Actions while health concern(F=7.896 p<.001) and subjective health status(F=9.913, p<.001) showed differences in the practice of Cancer Prevention Actions. Conclusion: These findings showed the gap between the perception and practice of cancer prevention actions. Considering the importance of individual characteristics, it is essential to develop a differentiated cancer prevention education program for college students. Also, nursing intervention program should be developed to raise the alertness of cancer in order to enhance cancer preventive practice.