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- 저자 : Changrong Chen (검색결과 4 건)
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Study of Heat Source Calibration and Modelling for Laser Welding Process
Changrong Chen,Yueh-Jaw Lin,Hengan Ou,Yan Wang 한국정밀공학회 2018 International Journal of Precision Engineering and Vol.19 No.8
Heat source model is an important part when carrying out simulations of welding processes. The calibration process involves a great amount of numerical simulations or theoretical deductions with many simplifications. In this paper, an interaction finite element and optimization algorithm package is programmed to automatically calibrate heat source models. The results are then used to establish mathematical relationships between parameters of heat source and welding process variables. The models show that the absorption efficiency and depth of heat source are exponential functions of depth of focus and laser power, respectively while radius of heat source is determined by depth of focus quadratically.
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Structure and electrical properties of Bi0.5(Na, K)0.5TiO3-BiGaO3 lead-free piezoelectric ceramics
Changrong Zhou,Xinyu Liu,Weizhou Li,Changlai Yuan,Guohua Chen 한국물리학회 2010 Current Applied Physics Vol.10 No.1
Lead-free piezoelectric ceramics (1 - x - y)Bi0.5Na0.5TiO3-xBi0.5K0.5TiO3- yBiGaO3 have been fabricated by an ordinary sintering technique, and their structure and electrical properties and depolarization temperature have been studied. The results of X-ray diffraction reveal that Bi0.5K0.5TiO3 and BiGaO3 diffuse into the Bi0.5Na0.5TiO3 lattices to form a new solid solution with a pure perovskite structure. An obvious change in microstructure with increasing concentration of Bi0.5K0.5TiO3 and BiGaO3 was observed. The piezoelectric constant d33 and the electromechanical coupling factor kp of the ceramics attain maximum values of 165 pC/N and 0.346 at y = 0.01(x = 0.18) and x = 0.21(y = 0.01), respectively. The temperature dependence of dielectric constant indicates an obvious relaxor characteristic with strong frequency dependence of dielectric constant. The depolarization temperature decreased with increasing content of BiGaO3 and first decreases and then increases with increasing amount of Bi0.5K0.5TiO3.
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In situ monitoring of pore structure of magnesium oxysulfate cement paste: Effect of MgSO4/H2O ratio
Shengwen Tang,Changrong Wei,Rongjin Cai,Jiasheng Huang,E. Chen,Junhui Yuan 한국공업화학회 2020 Journal of Industrial and Engineering Chemistry Vol.83 No.-
This work systematically presented the pore structure evolution of different magnesium oxysulfate(MOS) cement pastes by non-contact impedance measurement (NCIM), fractal theory and othermicrostructural experiments. According to the evolution of electrical impedance response, threehydration stages (dissolution, acceleration and hardened stages) can be identified in the pastes. Furthermore, based on the results obtained from NCIM and fractal theory, the porosity, incremental porevolume, pore tortuosity, average pore diameter and maximal pore diameter of MOS cement pastes areinvestigated. The influence of MgSO4/H2O ratio on pore structure of MOS cement paste is primarilyexplained. It can be inferred from predicted and experimental results that NCIM is a good method toanalyze the microstructure evolution of MOS cement pastes in-situ.
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( Qiuke Hou ),( Yongquan Huang ),( Changrong Zhang ),( Shuilian Zhu ),( Peiwu Li ),( Xinlin Chen ),( Zhengkun Hou ),( Fengbin Liu ) 대한소화기기능성질환·운동학회(구 대한소화관운동학회) 2018 Journal of Neurogastroenterology and Motility (JNM Vol.24 No.4
Background/Aims MicroRNAs (miRNAs) were reported to be responsible for intestinal permeability in diarrhea-predominant irritable bowel syndrome (IBS-D) rats in our previous study. However, whether and how miRNAs regulate visceral hypersensitivity in IBS-D remains largely unknown. Methods We established the IBS-D rat model and evaluated it using the nociceptive visceral hypersensitivity test, myeloperoxidase activity assay, restraint stress-induced defecation, and electromyographic (EMG) activity. The distal colon was subjected to miRNA microarray analysis followed by isolation and culture of colonic epithelial cells (CECs). Bioinformatic analysis and further experiments, including dual luciferase assays, quantitative real-time polymerase chain reaction, western blot, and enzyme-linked immunosorbent assay, were used to detect the expression of miRNAs and how it regulates visceral hypersensitivity in IBS-D rats. Results The IBS-D rat model was successfully established. A total of 24 miRNAs were differentially expressed in the distal colon of IBS-D rats; 9 were upregulated and 15 were downregulated. Among them, the most significant upregulation was miR-200a, accompanied by downregulation of cannabinoid receptor 1 (CNR1) and serotonin transporter (SERT). MiR-200a mimic markedly inhibited the expression of CNR1/SERT. Bioinformatic analysis and luciferase assay confirmed that CNR1/SERT are direct targets of miR-200a. Rescue experiments that overexpressed CNR1/SERT significantly abolished the inhibitory effect of miR-200a on the IBS-D rats CECs. Conclusions This study suggests that miR-200a could induce visceral hyperalgesia by targeting the downregulation of CNR1 and SERT, aggravating or leading to the development and progression of IBS-D. MiR-200a may be a regulator of visceral hypersensitivity, which provides potential targets for the treatment of IBS-D. (J Neurogastroenterol Motil 2018;24:656-668)
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