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RISS 인기검색어
- 검색키워드
- 저자 : Bettini, Paolo (검색결과 5 건)
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Clinical findings, rhinoscopy and histological evaluation of 54 dogs with chronic nasal disease
Marco Pietra,Flavio Pasquali,Noemi Romagnoli,Giuliano Bettini,Alessandro Spadari,Giuseppe Spinella 대한수의학회 2010 Journal of Veterinary Science Vol.11 No.3
Nasal diseases are very common in dogs and rhinoscopy is often required for a definitive diagnosis. Rhinoscopy, while superficial in nature, can guide the clinician to the final diagnosis. In this study, rhinoscopy was performed on 54 dogs with symptoms of chronic nasopharyngeal disease. The endoscopic diagnosis of neoplasia or chronic nasal inflammation was validated with histological examination of pathological samples, in order to evaluate the degree of concordance between endoscopic findings and histological diagnosis. The agreement between endoscopy and histology was tested by application of Cohen’s kappa coefficient. We conclude that correlation between endoscopic results and histological diagnosis, expressed by a Cohen’s kappa coefficient of 0.73,is only possible with a constant cooperation between the clinician and the pathologist.
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Faraz Deirmina,Sasan Amirabdollahian,Luke Harris,Eleonora Bettini,Raveendra Siriki,Massimo Pellizzari,Paolo Bosetti,Alberto Molinari 대한금속·재료학회 2023 METALS AND MATERIALS International Vol.29 No.10
Maraging steels are a class of low-carbon ultra-high-strength martensitic steels. Due to their excellent weldability, these steels have been widely applied for laser-based additive manufacturing (AM). MAR-60HRC is a newly developed maraging grade for AM with a nominal chemical composition of 13.0Ni-15.0Co-10.0Mo-0.2Ti, Fe bal. (wt%), capable of achieving hardness levels of ~ 740 HV. Alternatively, 18Ni300 is a commercialized maraging steel with an excellent combination of strength and toughness at the peak aged hardness (i.e., ~ 590 HV). This work aims to investigate the properties and microstructure of MAR-60HRC fabricated by Laser Directed Energy Deposition (L-DED). Further, the manufacturability of bimetallic parts comprising a tough 18Ni300 core and a hard MAR-60HRC on the surface was evaluated. After proper aging, the multi-layered material showed a surface hardness of ~ 720 HV1 and apparent fracture toughness of 71 MPa m1/2, higher than that of MAR-60HRC (i.e., 60 MPa m1/2), and lower than 18Ni300 (i.e., 90 MPa m1/2). The excellent combination of surface hardness and fracture toughness was discussed, considering the crack arrest at the interface and the flawless interface between the two steels.
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Immunohistochemical expression of h-telomerase reversetranscriptase in canine and feline meningiomas
Luciana Mandrioli,Alessandro Cesari,Maria Teresa Mandara,Paolo Stefano Marcato,Giuliano Bettini,Serena Panarese 대한수의학회 2007 Journal of Veterinary Science Vol.8 No.2
Telomere length maintenance is regarded as a fundamental step in tumorigenesis, as most human brain tumors, including meningiomas, stabilize the ends of their chromosomes using telomerase. This investigation represents an introduction to telomerase expression in canine and feline meningiomas. Twenty-five archived cases (14 dogs and 11 cats) were immunohistochemically tested for human-telomerase reverse transcriptase (h- TERT), scored, and quantified; furthermore, mitoses were counted on sections stained with a modified toluidine blue. The h-TERT antibody immunolabelled the nucleus and nucleolus of meningeal neoplastic cells, with an intensity ranging from mild to strong and a speckled distribution; a significantly higher expression in cats was noted, while no significant association between h-TERT immunolabelling and sex or histotype was evident in dogs or cats. The telomerase enzyme represents a fundamental parameter of potential malignant transformation, which may occur independently of the signal to proliferate, thereby supplying the cells with unlimited growth capabilities. Telomerase expression could be a prognostic indicator independent of the kinetic parameters, although this should be evaluated using a larger dataset with available clinical information.
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An atypical case of respiratory actinobacillosis in a cow
Peli Angelo,Spadari Alessandro,Romagnoli Noemi,Scarpa Filippo,Pietra Marco,Bettini Giuliano 대한수의학회 2009 Journal of Veterinary Science Vol.10 No.3
A not pregnant 4-year-old Jersey cow was presented with the sudden appearance of respiratory noise, nasal discharge and moderate respiratory difficulty. Upon physical examination a snoring-like noise, extended head and neck position, exaggerated abdominal effort, bilateral nasal discharge and left prescapular lymph node enlargement were noted. Sub-occlusion of the initial portion of the respiratory tract was suspected. Radiographic and endoscopic examinations revealed a pedunculate mass on the dorsal aspect of the rhinopharynx, which was removed with endoscopically assisted electrosurgery. Histologic examination revealed a chronic pyogranulomatous inflammation with eosinophilic club-like bodies surrounding small colonies of rod-shaped bacteria. Results of histochemical staining were consistent with Actinobacillus-like bacteria and a diagnosis of respiratory actinobacillosis was reached. Surgery and antibiotic therapy were resolutive, as demonstated by an endoscopic check at the second month after surgery, even without the association of the traditional iodine cure, which is regarded as the treatment of choice for actinobacillosis.
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Fiber optic shape sensor system for a morphing wing trailing edge
Ciminello, Monica,Ameduri, Salvatore,Concilio, Antonio,Dimino, Ignazio,Bettini, Paolo Techno-Press 2017 Smart Structures and Systems, An International Jou Vol.20 No.4
The objective of this work is to present a conceptual design and the modelling of a distributed sensor system based on fiber optic devices (Fiber Bragg Grating, FBG), aimed at measuring span-wise and chord-wise variations of an adaptive (morphing) trailing edge. The network is made of two different integrated solutions for revealing deformations of the reference morphing structure. Strains are confined to typical values along the span (length) but they are expected to overcome standard ranges along the chord (width), up to almost 10%. In this case, suitable architectures may introduce proper modulations to keep the measured deformation low while preserving the information content. In the current paper, the designed monitoring system combines the use of a span-wise fiber reinforced patch with a chord-wise sliding beam. The two elements make up a closed grid, allowing the reconstruction of the complete deformed shape under the acceptable assumption that the transformation refers to regular geometry variations. Herein, the design logic and some integration issues are reported. Preliminary experimental test results are finally presented.
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