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- 저자 : Pietra Marco (검색결과 4 건)
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Clinical findings, rhinoscopy and histological evaluation of 54 dogs with chronic nasal disease
Marco Pietra,Flavio Pasquali,Noemi Romagnoli,Giuliano Bettini,Alessandro Spadari,Giuseppe Spinella 대한수의학회 2010 Journal of Veterinary Science Vol.11 No.3
Nasal diseases are very common in dogs and rhinoscopy is often required for a definitive diagnosis. Rhinoscopy, while superficial in nature, can guide the clinician to the final diagnosis. In this study, rhinoscopy was performed on 54 dogs with symptoms of chronic nasopharyngeal disease. The endoscopic diagnosis of neoplasia or chronic nasal inflammation was validated with histological examination of pathological samples, in order to evaluate the degree of concordance between endoscopic findings and histological diagnosis. The agreement between endoscopy and histology was tested by application of Cohen’s kappa coefficient. We conclude that correlation between endoscopic results and histological diagnosis, expressed by a Cohen’s kappa coefficient of 0.73,is only possible with a constant cooperation between the clinician and the pathologist.
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Francesca Bresciani,Marco Pietra,Sara Corradini,Massimo Giunti,Federico Fracassi 대한수의학회 2014 Journal of Veterinary Science Vol.15 No.2
In human medicine, diagnosis of diabetic ketoacidosis(DKA) is usually based on measurement of capillary3-β-hydroxybutyrate (3-HB) with a hand held ketonesensor. This study was conducted to determine ifmeasurement of capillary 3-HB could be useful for thediagnosis and monitoring of canine DKA. Fifteen dogs withdiabetic ketosis and 10 with DKA were evaluated. Pairedmeasurements of 3-HB of capillary and venous bloodsamples were analysed by the electrochemical sensor andreference method. Use of capillary 3-HB measurementduring DKA management was then evaluated throughsimultaneous measurements of capillary 3-HB, urinaryAcAc and venous blood gas analysis. Good agreementbetween capillary and venous 3-HB measurement wasdetected by the electrochemical sensor and referencemethod. Monitoring treatment of DKA revealed asignificant correlation between capillary 3-HB and acidosismarkers, while no significant correlation was observedbetween AcAc and acidosis markers. A cut-off value ofcapillary blood 3-HB >3.8 mmol/L for diagnosis of DKAresulted in 70% and 92% sensitivity and specificity. Theelectrochemical sensor accurately measures 3-HBconcentration in both capillary and venous blood samples, isaccurate in diagnosing canine DKA, and appears to reflectthe patient’s metabolic status during DKA treatment.
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Serum homocysteine concentration in dogs with immunosuppressant-responsive enteropathy
Elena Benvenuti,Alessio Pierini,Eleonora Gori,Enrico Botter,Marco Pietra,Ilaria Lippi,Valentina Meucci,Veronica Marchetti 대한수의학회 2020 Journal of Veterinary Science Vol.21 No.4
Background: Homocysteine (HCY) was evaluated in healthy and chronic enteropathic dogs, however no studies on dogs with immunosuppressant-responsive enteropathy are available. Objectives: The aim was to evaluate serum HCY concentrations and its prognostic role in dogs with immunosuppressant-responsive enteropathy compared to healthy dogs. Methods: Serum HCY concentration was statistically compared between 24 healthy dogs and 29 dogs with immunosuppressant-responsive enteropathy. Correlation analyses between serum total protein, albumin (ALB), C-reactive protein (CRP), folate and cobalamin, and serum HCY concentration were performed in immunosuppressant-responsive enteropathic dogs. Results: The associations between serum HCY concentration and clinical, histological, endoscopic scores and follow-up were evaluated. Mean serum HCY concentration was higher in immunosuppressant-responsive enteropathic dogs compared to control dogs (30.22 ± 8.67 μmol/L vs. 5.26 ± 2.78 μmol/L; p < 0.0001). No association between serum HCY concentration and total protein, ALB, CRP, folate concentration as well as, clinical score, histological and endoscopic scores was found. A negative correlation between serum HCY concentration and cobalamin was noted (p = 0.0025, r = −0.54). No significant difference in HCY was found between responsive and non-responsive dogs or between survivors and non-survivors. Conclusions: Although, serum HCY concentration was higher in immunosuppressant-responsive enteropathy, its prognostic value remains unclear. However, further prospective, large-scale studies are warranted to better investigate the possible prognostic role of HCY in immunosuppressant-responsive enteropathic dogs.
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An atypical case of respiratory actinobacillosis in a cow
Peli Angelo,Spadari Alessandro,Romagnoli Noemi,Scarpa Filippo,Pietra Marco,Bettini Giuliano 대한수의학회 2009 Journal of Veterinary Science Vol.10 No.3
A not pregnant 4-year-old Jersey cow was presented with the sudden appearance of respiratory noise, nasal discharge and moderate respiratory difficulty. Upon physical examination a snoring-like noise, extended head and neck position, exaggerated abdominal effort, bilateral nasal discharge and left prescapular lymph node enlargement were noted. Sub-occlusion of the initial portion of the respiratory tract was suspected. Radiographic and endoscopic examinations revealed a pedunculate mass on the dorsal aspect of the rhinopharynx, which was removed with endoscopically assisted electrosurgery. Histologic examination revealed a chronic pyogranulomatous inflammation with eosinophilic club-like bodies surrounding small colonies of rod-shaped bacteria. Results of histochemical staining were consistent with Actinobacillus-like bacteria and a diagnosis of respiratory actinobacillosis was reached. Surgery and antibiotic therapy were resolutive, as demonstated by an endoscopic check at the second month after surgery, even without the association of the traditional iodine cure, which is regarded as the treatment of choice for actinobacillosis.
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