On primary decompositions and radicals of submodules

M. Alkan,B. Saraç 장전수학회 2007 Proceedings of the Jangjeon mathematical society Vol.10 No.1

In this paper, we give some characterizations for prime and primary submodules of a …nitely generated free modules over PID’s and determine the height of prime submodules. We also char- acterize the minimal primary decompositions and radicals of submodules of any …nitely generated free module over a PID.

Recurrent <i>ETNK1</i> mutations in atypical chronic myeloid leukemia

Gambacorti-Passerini, Carlo B.,Donadoni, Carla,Parmiani, Andrea,Pirola, Alessandra,Redaelli, Sara,Signore, Giovanni,Piazza, Vincenzo,Malcovati, Luca,Fontana, Diletta,Spinelli, Roberta,Magistroni, Vera American Society of Hematology 2015 Blood Vol.125 No.3

<P>Despite the recent identification of recurrent <I>SETBP1</I> mutations in atypical chronic myeloid leukemia (aCML), a complete description of the somatic lesions responsible for the onset of this disorder is still lacking. To find additional somatic abnormalities in aCML, we performed whole-exome sequencing on 15 aCML cases. In 2 cases (13.3%), we identified somatic missense mutations in the <I>ETNK1</I> gene. Targeted resequencing on 515 hematological clonal disorders revealed the presence of <I>ETNK1</I> variants in 6 (8.8%) of 68 aCML and 2 (2.6%) of 77 chronic myelomonocytic leukemia samples. These mutations clustered in a small region of the kinase domain, encoding for H243Y and N244S (1/8 H243Y; 7/8 N244S). They were all heterozygous and present in the dominant clone. The intracellular phosphoethanolamine/phosphocholine ratio was, on average, 5.2-fold lower in ETNK1-mutated samples (<I>P</I> < .05). Similar results were obtained using myeloid TF1 cells transduced with ETNK1 wild type, ETNK1-N244S, and ETNK1-H243Y, where the intracellular phosphoethanolamine/phosphocholine ratio was significantly lower in ETNK1-N244S (0.76 ± 0.07) and ETNK1-H243Y (0.37 ± 0.02) than in ETNK1-WT (1.37 ± 0.32; <I>P</I> = .01 and <I>P</I> = .0008, respectively), suggesting that <I>ETNK1</I> mutations may inhibit the catalytic activity of the enzyme. In summary, our study shows for the first time the evidence of recurrent somatic <I>ETNK1</I> mutations in the context of myeloproliferative/myelodysplastic disorders.</P>

Is Anything Ever New? Fashion Design Students` Perceptions of Piracy

Sara B. Marcketti,Kate Greder,Heather Sin Clair 한국복식학회 2014 International journal of costume and fashion Vol.14 No.1

Design piracy is the unauthorized copying of another designer or manufacturer’s work. While controversial, it is an institutionalized practice in the apparel industry. The purpose of this study was to better understand student perceptions of design piracy, particularly as it is one they will encounter in their future careers. The authors interviewed twenty-four apparel design students at a land-grant Midwestern University. Data was analyzed using theme analysis. Three themes developed including: 1) Expressions of cognitive dissonance in statements expressing enjoyment of the practice of design piracy as a consumer; yet disappointment when (and if) their own design work was copied. 2) Concerns regarding the definition of originality and the logistics of enforcing a plan against design piracy. 3) Differences of opinion regarding the prevalence of the practice, particularly if the students had industry experience or not. Advice for professors from students regarding piracy is included.

Sedentary Time is Associated with Worse Attention in Parkinson’s Disease: A Pilot Study

Sara B. W. Troutman,Kirk I. Erickson,George Grove,Andrea M. Weinstein 대한파킨슨병및이상운동질환학회 2020 Journal Of Movement Disorders Vol.13 No.2

ObjectiveaaCognitive symptoms of Parkinson’s disease (PD) may be alleviated by moderate-to-vigorous physical activity(MVPA), but no published research has characterized the relationship between objectively measured sedentary behavior andcognitive symptoms of PD. Therefore, the objective of this study was to assess the cross-sectional relationship between sedentarytime and cognitive performance in a small pilot sample of individuals with mild-to-moderate PD. MethodsaaObjective measures of sedentary time were obtained using an armband accelerometer. Cognition was assessed withthe Parkinson’s Disease Cognitive Rating Scale and a computerized task-switching paradigm. ResultsaaThe percentage of awake time spent in sedentary activities was negatively correlated with attention (β = -14.20, t(12)= -2.47, p = 0.03) but not other cognitive domains (p > 0.05) after controlling for MVPA and medication dosage. ConclusionaaSedentary activity may have unique associations with cognition, particularly attention, over and above MVPA inindividuals with PD.

Charge density wave order in 1D mirror twin boundaries of single-layer MoSe₂

Barja, Sara,Wickenburg, Sebastian,Liu, Zhen-Fei,Zhang, Yi,Ryu, Hyejin,Ugeda, Miguel ,M.,Hussain, Zahid,Shen, Zhi-Xun,Mo, Sung-Kwan,Wong, Ed,Salmeron, Miquel ,B.,Wang, Feng,Crommie, Michael F. NATURE PUBLISHING GROUP 2016 NATURE PHYSICS Vol.12 No.8

We provide direct evidence for the existence of isolated, one-dimensional charge density waves at mirror twin boundaries (MTBs) of single-layer semiconducting MoSe<SUB>2</SUB>. Such MTBs have been previously observed by transmission electron microscopy and have been predicted to be metallic in MoSe<SUB>2</SUB> and MoS<SUB>2</SUB>. Our low-temperature scanning tunnelling microscopy/spectroscopy measurements revealed a substantial bandgap of 100 meV opening at the Fermi energy in the otherwise metallic one-dimensional structures. We found a periodic modulation in the density of states along the MTB, with a wavelength of approximately three lattice constants. In addition to mapping the energy-dependent density of states, we determined the atomic structure and bonding of the MTB through simultaneous high-resolution non-contact atomic force microscopy. Density functional theory calculations based on the observed structure reproduced both the gap opening and the spatially resolved density of states.

Anti-Stress Effect of GABA Enriched Brown Rice Flakes (Cereal) on Immobilized Stress Rat Model

Shalom Sara Thomas,Ravichandran Vijaya Abinaya,P.B. Tirupati Pichiah,Mi Sun Kim,Youn-Soo Cha 한국식품영양과학회 2015 한국식품영양과학회 학술대회발표집 Vol.2015 No.8

Is Anything Ever New? Fashion Design Students' Perceptions of Piracy

Marcketti, Sara B.,Greder, Kate,Sinclair, Heather The Korean Society of Costume 2014 International journal of costume and fashion Vol.14 No.1

Design piracy is the unauthorized copying of another designer or manufacturer's work. While controversial, it is an institutionalized practice in the apparel industry. The purpose of this study was to better understand student perceptions of design piracy, particularly as it is one they will encounter in their future careers. The authors interviewed twenty-four apparel design students at a land-grant Midwestern University. Data was analyzed using theme analysis. Three themes developed including: 1) Expressions of cognitive dissonance in statements expressing enjoyment of the practice of design piracy as a consumer; yet disappointment when (and if) their own design work was copied. 2) Concerns regarding the definition of originality and the logistics of enforcing a plan against design piracy. 3) Differences of opinion regarding the prevalence of the practice, particularly if the students had industry experience or not. Advice for professors from students regarding piracy is included.

Membrane-wrapped nanoparticles for photothermal cancer therapy

Aboeleneen Sara B.,Scully Mackenzie A.,Harris Jenna C.,Sterin Eric H.,Day Emily S. 나노기술연구협의회 2022 Nano Convergence Vol.9 No.37

Cancer is a global health problem that needs effective treatment strategies. Conventional treatments for solid-tumor cancers are unsatisfactory because they cause unintended harm to healthy tissues and are susceptible to cancer cell resistance. Nanoparticle-mediated photothermal therapy is a minimally invasive treatment for solid-tumor cancers that has immense promise as a standalone therapy or adjuvant to other treatments like chemotherapy, immunotherapy, or radiotherapy. To maximize the success of photothermal therapy, light-responsive nanoparticles can be camouflaged with cell membranes to endow them with unique biointerfacing capabilities that reduce opsonization, prolong systemic circulation, and improve tumor delivery through enhanced passive accumulation or homotypic targeting. This ensures a sufficient dose of photoresponsive nanoparticles arrives at tumor sites to enable their complete thermal ablation. This review summarizes the state-of-the-art in cell membrane camouflaged nanoparticles for photothermal cancer therapy and provides insights to the path forward for clinical translation.

Design Active Robot Controller for Dental Automation

Farzin Piltan,Sara Yekband,Rezvan Mirzaie,Samira Soltani,Nasri. B Sulaiman,Amin Jalali 보안공학연구지원센터 2015 International Journal of u- and e- Service, Scienc Vol.8 No.4

Following the developments in industrial robot technology, robotics has found its way into the medical field and is used in a range of surgical disciplines. The main purpose of the use of robots is to increase the precision, quality and safety of surgical procedures. Robotics is not yet used in dentistry even though all the necessary technologies have already been developed and could easily be adapted. Some of the technologies are already used in dentistry, such as image-based simulation of implant surgery followed by the use of surgical guides, and creating digital impressions of pre parathions using an intra-oral scanner, after which a milling device produces the restoration, but we have not yet seen any robot able to prepare teeth for crowns, inlays or bridges. Such a robot would fundamentally be a dental drilling device coupled with a navigation device to determine the correct position of the device in relation to the patient. The robot would either be operated directly by a dentist or be preprogrammed to perform its functions based on imaging data (CT scan). Finally, an intra-oral scanner would be used to make digital impressions. This data would then be transferred to the lab to produce temporary crowns or bridges in a very short time using a milling machine and to manufacture the final restorations in much shorter time than with conventional procedures. Robotics could offer dentistry improved accuracy, predictability, safety, quality of care and speed of treatment. One might wonder why robots have not yet been introduced to dentistry, as the functions needed are relatively simple. An explanation could be that robotics in dentistry is an example of a disruptive technology, meaning that the current manufacturers of dental equipment might fear a negative effect on their current business and the alienation of dentists, as robots might be seen as a threat to dental professionals. The passive robotic arm will sense the patient’s movement, sending feedback in the form of translation and rotation data to the dental robot giving it the capability to adjust. This device will address the age-old problem in dentistry – precision and safety. This research focuses on the intelligent control of dental drilling procedures on a stationary object. This project addresses the ability of the system to detect movement of the object and accordingly adjust the drill before continuing the procedure.

Synthesis of Evidence to Support EMS Personnel's Mental Health During Disease Outbreaks: A Scoping Review

Du Bronson B.,Rezvani Sara,Bigelow Philip,Nowrouzi-Kia Behdin,Boscart Veronique M.,Yung Marcus,Yazdani Amin 한국산업안전보건공단 산업안전보건연구원 2022 Safety and health at work Vol.13 No.4

Emergency medical services (EMS) personnel are at high risk for adverse mental health outcomes during disease outbreaks. To support the development of evidence-informed mitigation strategies, we conducted a scoping review to identify the extent of research pertaining to EMS personnel's mental health during disease outbreaks and summarized key factors associated with mental health outcomes. We systematically searched three databases for articles containing keywords within three concepts: EMS personnel, disease outbreaks, and mental health. We screened and retained original peer-reviewed articles that discussed, in English, EMS personnel's mental health during disease outbreaks. Where inferential statistics were reported, the associations between individual and work-related factors and mental health outcomes were synthesized. Twenty-five articles were eligible for data extraction. Our findings suggest that many of the contributing factors for adverse mental health outcomes are related to inadequacies in fulfilling EMS personnel's basic safety and informational needs. In preparation for future disease outbreaks, resources should be prioritized toward ensuring adequate provisions of personal protective equipment and infection prevention and control training. This scoping review serves as a launching pad for further research and intervention development.