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Exclusive Enteral Nutrition for the Treatment of Pediatric Crohn's Disease: The Patient Perspective
Stephanie Christine Brown,Catherine L Wall,Richard B Gearry,Andrew S Day The Korean Society of Pediatric Gastroenterology 2023 Pediatric gastroenterology, hepatology & nutrition Vol.26 No.3
Crohn's disease (CD) is a chronic, incurable and relapsing disease involving any part of the gastrointestinal tract and exclusive enteral nutrition (EEN) is first-line therapy. Few studies have examined the patient experience of EEN. The aim of this study was to assess the child's experiences of EEN, to identify problematic themes and understand the child's mindset. Children with CD who previously completed EEN were recruited to complete a survey. All data were analyzed using Microsoft Excel and reported as N (%). Forty-four children (mean age 11.3 years) consented to participate. Sixty-eight percent of children reported limited formula flavors as the most challenging aspect and 68% of children identified 'support' to be important. This study highlights the psychological impact of chronic disease and its therapies on children. Providing adequate support is essential to insure EEN is successful. Further studies are required to determine psychological support strategies for children taking EEN.
Brown, Richard J. C.,Kumar, Yarshini,Brown, Andrew S.,Kim, Ki-Hyun American Chemical Society 2011 Environmental science & technology Vol.45 No.18
<P>The short- and long-term memory effects associated with measurements of mercury vapor in air using gold-coated silica adsorption tubes have been described. Data are presented to quantify these effects and to determine their dependence on certain relevant measurement parameters, such as number of heating cycles used for each analysis, age of adsorption tube, mass of mercury on adsorption tube, and the length of time between analyses. The results suggest that the long-term memory effect is due to absorption of mercury within the bulk gold in the adsorption tube, which may only be fully liberated by allowing enough time for this mercury to diffuse to the gold surface. The implications of these effects for air quality networks making these measurements routinely has been discussed, and recommendations have been made to ensure any measurement bias is minimized.</P><P><B>Graphic Abstract</B> <IMG SRC='http://pubs.acs.org/appl/literatum/publisher/achs/journals/content/esthag/2011/esthag.2011.45.issue-18/es201454u/production/images/medium/es-2011-01454u_0001.gif'></P><P><A href='http://pubs.acs.org/doi/suppl/10.1021/es201454u'>ACS Electronic Supporting Info</A></P>
A temperature-based approach to predicting lost data from highly seasonal pollutant data sets
Brown, Richard J. C.,Brown, Andrew S.,Kim, Ki-Hyun The Royal Society of Chemistry 2013 Environmental science Vol.15 No.6
<P>A new technique to predict concentrations of benzo[<I>a</I>]pyrene (B<I>a</I>P) in ambient air during periods of lost data has been developed and tested. This new technique is based on the relationship between ambient temperature and B<I>a</I>P concentration observed at individual monitoring stations over many years. The technique has been tested on monthly data of B<I>a</I>P concentrations in PM<SUB>10</SUB> at individual monitoring stations on the UK PAH Monitoring Network. The annual average concentration values produced with and without the use of predicted data have been compared to the actual annual averages in the absence of any data loss. The use of predicted data is a significant improvement when compared with the averages produced in the absence of any data prediction and outperforms previous prediction strategies associated with intra-year trends. Furthermore the technique is suitable for the prediction of long periods of missing data, which other prediction techniques have not been able to deal with satisfactorily.</P> <P>Graphic Abstract</P><P>A temperature-based approach to predicting lost data from highly seasonal pollutant data sets is presented. <IMG SRC='http://pubs.rsc.org/services/images/RSCpubs.ePlatform.Service.FreeContent.ImageService.svc/ImageService/image/GA?id=c3em00131h'> </P>
LEGACY EXTRAGALACTIC UV SURVEY (LEGUS) WITH THE<i>HUBBLE SPACE TELESCOPE</i>. I. SURVEY DESCRIPTION
Calzetti, D.,Lee, J. C.,Sabbi, E.,Adamo, A.,Smith, L. J.,Andrews, J. E.,Ubeda, L.,Bright, S. N.,Thilker, D.,Aloisi, A.,Brown, T. M.,Chandar, R.,Christian, C.,Cignoni, M.,Clayton, G. C.,Silva, R. da,Mi IOP Publishing 2015 The Astronomical journal Vol.149 No.2
Wafer-scale synthesis of monolayer two-dimensional porphyrin polymers for hybrid superlattices
Zhong, Yu,Cheng, Baorui,Park, Chibeom,Ray, Ariana,Brown, Sarah,Mujid, Fauzia,Lee, Jae-Ung,Zhou, Hua,Suh, Joonki,Lee, Kan-Heng,Mannix, Andrew J.,Kang, Kibum,Sibener, S. J.,Muller, David A.,Park, Jiwoon American Association for the Advancement of Scienc 2019 Science Vol.366 No.6471
<P><B>Single-layer porphyrin polymerization</B></P><P>Two-dimensional polymers can be made as monolayer sheets through controlled synthesis at an interface. However, it is often difficult to create intact sheets over large areas that can be transferred onto substrates. Zhong <I>et al.</I> polymerized derivatized porphyrin molecules during laminar flow at a sharp pentane-water interface to form sheets that are 5 centimeters in diameter (see the Perspective by MacLean and Rosei). The authors used electron microscopy and spectroscopy to confirm that they had produced intact monolayers. These films were then transferred onto monolayer sheets of molybdenum disulfide to form superlattices for use as capacitors.</P><P><I>Science</I>, this issue p. 1379; see also p. 1308</P><P>The large-scale synthesis of high-quality thin films with extensive tunability derived from molecular building blocks will advance the development of artificial solids with designed functionalities. We report the synthesis of two-dimensional (2D) porphyrin polymer films with wafer-scale homogeneity in the ultimate limit of monolayer thickness by growing films at a sharp pentane/water interface, which allows the fabrication of their hybrid superlattices. Laminar assembly polymerization of porphyrin monomers could form monolayers of metal-organic frameworks with Cu<SUP>2+</SUP> linkers or covalent organic frameworks with terephthalaldehyde linkers. Both the lattice structures and optical properties of these 2D films were directly controlled by the molecular monomers and polymerization chemistries. The 2D polymers were used to fabricate arrays of hybrid superlattices with molybdenum disulfide that could be used in electrical capacitors.</P>