Epigallocatechin-3-gallate prior to composite resin in abfraction lesions: a split-mouth randomized clinical trial

Alves Luísa Valente Gotardo Lara,Fracasso Lisiane Martins,Cortez Thiago Vinicius,Souza-Gabriel Aline Evangelista,Corona Silmara Aparecida Milori 대한치과보존학회 2023 Restorative Dentistry & Endodontics Vol.48 No.2

Objectives Natural extracts have been investigated as a biomimetic strategy to mechanically strengthen the collagen network and control the biodegradation of extracellular matrix. This study evaluated the effect of epigallocatechin-3-gallate (EGCG) on abfraction lesions prior to the composite resin. Materials and Methods The sample consisted of 30 patients (aged between 28 and 60 years) with abfraction lesions located in 2 homologous premolars. The teeth were randomly assigned according to dentin treatment: 0.02% EGCG solution or distilled water (control). After enamel acid etching, the solutions were applied immediately for 1 minute. The teeth were restored with Universal Adhesive (3M) and Filtek Z350 XT (3M). Analyzes were done by 2 independent examiners using modified USPHS (retention, secondary caries, marginal adaptation, and postoperative sensitivity) and photographic (color, marginal pigmentation, and anatomical form) criteria at baseline (7 days) and final (18 months). The data analysis used Friedman and Wilcoxon signed-rank tests (α = 0.05). Results At baseline, all restorations were evaluated as alpha for all criteria. After 18 months, restorations were evaluated as alpha for secondary caries, color, and marginal pigmentation. There was significant difference between baseline and 18 months (p = 0.009) for marginal adaptation and postoperative sensitivity (p = 0.029), but no significant difference were verified between treatments (p = 0.433). The EGCG group had a restoration retention rate of 93.3%, while the control group had 96.7%. Conclusions The application of EGCG solution on abfraction lesions did not significantly influence the survival of the restorations based on clinical and photographic criteria. Objectives Natural extracts have been investigated as a biomimetic strategy to mechanically strengthen the collagen network and control the biodegradation of extracellular matrix. This study evaluated the effect of epigallocatechin-3-gallate (EGCG) on abfraction lesions prior to the composite resin. Materials and Methods The sample consisted of 30 patients (aged between 28 and 60 years) with abfraction lesions located in 2 homologous premolars. The teeth were randomly assigned according to dentin treatment: 0.02% EGCG solution or distilled water (control). After enamel acid etching, the solutions were applied immediately for 1 minute. The teeth were restored with Universal Adhesive (3M) and Filtek Z350 XT (3M). Analyzes were done by 2 independent examiners using modified USPHS (retention, secondary caries, marginal adaptation, and postoperative sensitivity) and photographic (color, marginal pigmentation, and anatomical form) criteria at baseline (7 days) and final (18 months). The data analysis used Friedman and Wilcoxon signed-rank tests (α = 0.05). Results At baseline, all restorations were evaluated as alpha for all criteria. After 18 months, restorations were evaluated as alpha for secondary caries, color, and marginal pigmentation. There was significant difference between baseline and 18 months (p = 0.009) for marginal adaptation and postoperative sensitivity (p = 0.029), but no significant difference were verified between treatments (p = 0.433). The EGCG group had a restoration retention rate of 93.3%, while the control group had 96.7%. Conclusions The application of EGCG solution on abfraction lesions did not significantly influence the survival of the restorations based on clinical and photographic criteria.

Methodologies for the Determination of Endogenous Phosphorus Losses in Growing Pigs

Alves, Debora Aline,da Rocha, Leonardo Tombesi,dos Santos Camargo, Claudiele Aparecida,Figueiredo, Andriele Medianeira,Ceron, Marcos Speroni,Lucca, Walter,Zanella, Irineo,de Oliveira, Vladimir Asian Australasian Association of Animal Productio 2016 Animal Bioscience Vol.29 No.11

A study was conducted to compare the endogenous basal losses of phosphorus (EBLP) in pigs fed diets containing gelatin (GEL) or spray-dried porcine plasma (SDPP) as protein sources and to determine the standardized total tract digestibility (STTD) of phosphorus (P) in SDPP. The trial was carried out at the Federal University of Santa Maria, Brazil. Twelve castrated pigs with an initial body weight of 55 kg were individually allotted in metabolic crates during two 12-day periods, each with 7 days of adaptation and 5 days of total fecal collection. The beginning and the end of the collecting periods were determined according to the marker-to-marker approach, using ferric oxide as an indigestible marker. Pigs were submitted to four semi-purified diets, one being a P-free diet with 30% of GEL as the protein source and three were diets with 10%, 20%, and 30% inclusion of SDPP respectively. Data were subjected to analysis of variance and the model included the effects of period, animal and treatments; the results of the three diets with increased levels of SDPP were subjected to linear regression analysis. The intercept of the relation of between ingested P and absorbed P represented the EBLP, while the slope indicated the STTD of P in SDPP. The EBLP means obtained by P-free diet and regression method were compared with the Student t test. The EBLP were 128.95 mg/kg dry matter intake (DMI) and 153.63 mg/kg DMI (standard error = 77.0; p<0.06) using the P-free diet with GEL as the protein source and the regression method, obtained with diets containing increased levels of SDPP, respectively. The apparent digestibility of P was 87.9%, 94.2%, and 92.9% for the treatments containing 10%, 20%, and 30% inclusion of SDPP, respectively. The estimated STTD of P obtained with the linear regression was 97.4%. When the EBLP estimated by the P-free diet was used to corrected the apparent digestibility of P in diets containing SDPP, the STTD of P in SDPP was 96.9%, 98.8%, and 95.9% for 10%, 20%, and 30% SDPP, respectively. Therefore, it can be concluded that SDPP can replace GEL to estimate the endogenous losses of P. In addition, the STTD of P in SDPP estimated with the P-free diet was 97.2% and it was 97.4% by the regression method, utilizing SDPP.

SPIF-A: on the development of a new concept of incremental forming machine

Alves de Sousa, R.J.,Ferreira, J.A.F.,Sa de Farias, J.B.,Torrao, J.N.D.,Afonso, D.G.,Martins, M.A.B.E. Techno-Press 2014 Structural Engineering and Mechanics, An Int'l Jou Vol.49 No.5

This paper presents the design and project of an innovative concept for a Single Point Incremental Forming (SPIF) Machine. Nowadays, equipment currently available for conducting SPIF result mostly from the adaptation of conventional CNC machine tools that results in a limited range of applications in terms of materials and geometries. There is also a limited market supply of equipment dedicated to Incremental Sheet Forming (ISF), that are costly considering low batches, making it unattractive for industry. Other factors impairing a quicker spread of SPIF are large forming times and poor geometrical accuracy of parts. The following sections will depict the development of a new equipment, designed to overcome some of the limitations of machines currently used, allowing the development of a sounding basis for further studies on the particular features of this process. The equipment here described possesses six-degrees-of freedom for the tool, for the sake of improved flexibility in terms of achievable tool-paths and an extra stiffness provided by a parallel kinematics scheme. A brief state of the art about the existing SPIF machines is provided to support the project's guidelines.

Analysis of etching at a solid-solid interface

Alves, Washington S.,Rodrigues, Evandro A.,Fernandes, Henrique A.,Mello, Bernardo A.,Oliveira, Fernando A.,Costa, Ismael V. L. American Physical Society 2016 Physical review. E Vol.94 No.4

Prediction of the dynamic flow stress

Alves, Marcilio Techno-Press 2005 Structural Engineering and Mechanics, An Int'l Jou Vol.20 No.5

This article explores a constitutive equation that is able to correlate stress, strain and strain rate. In order to show the advantages of the constitutive equation here proposed and how its material parameters are obtained, data extracted from the literature, for materials as different as polymers and metallic alloys, are used. Finite element simulation of the impact behaviour of a beam is presented to highlight the care one needs to exercise when using the more traditional Cowper-Symonds equation. The present constitutive equation has shown to be accurate for a wide range of strains, stresses and strain rates.

Implications of strong intergalactic magnetic fields for ultrahigh-energy cosmic-ray astronomy

Alves Batista, Rafael,Shin, Min-Su,Devriendt, Julien,Semikoz, Dmitri,Sigl, Guenter American Physical Society 2017 Physical review. D Vol.96 No.2

<P>We study the propagation of ultrahigh-energy cosmic rays in the magnetized cosmic web. We focus on the particular case of highly magnetized voids (B similar to nG), using the upper bounds from the Planck satellite. The cosmic web was obtained from purely magnetohydrodynamical cosmological simulations of structure formation considering different power spectra for the seed magnetic field in order to account for theoretical uncertainties. We investigate the impact of these uncertainties on the propagation of cosmic rays, showing that they can affect the measured spectrum and composition by up to. similar or equal to 80% and. similar or equal to 5%, respectively. In our scenarios, even if magnetic fields in voids are strong, deflections of 50 EeV protons from sources closer than similar to 50 Mpc are less than 15 degrees in approximately 10-50% of the sky, depending on the distribution of sources and magnetic power spectrum. Therefore, UHECR astronomy might be possible in a significant portion of the sky depending on the primordial magnetic power spectrum, provided that protons constitute a sizeable fraction of the observed UHECR flux.</P>

Malignant Posterior Reversible Encephalopathy Syndrome: A Case of Posterior Irreversible Encephalopathy Syndrome

William Alves Martins,Luiz Carlos Porcello Marrone 대한신경과학회 2016 Journal of Clinical Neurology Vol.12 No.2

Prediction of the dynamic flow stress

Marcilio Alves 국제구조공학회 2005 Structural Engineering and Mechanics, An Int'l Jou Vol.20 No.5

Carcass characteristics of lambs fed diets with increasing levels of crude glycerin

Caio Alves da Costa,Francisco Fernando Ramos de Carvalho,Adriana Guim,Gilcifran Prestes de Andrade,Daniel Barros Cardoso,Michel do Vale Maciel,Gabriela Goncalves da Silva,Andreza Guedes de Oliveira Na 아세아·태평양축산학회 2019 Animal Bioscience Vol.32 No.12

Objective: An experiment was conducted to evaluate the effects of increasing levels of crude glycerin (0%, 6%, 12%, and 18%) used as a substitute for corn in lamb feed on the quantitative characteristics of the carcass. Methods: A total of 40 crossbred Santa Inês lambs that were four months old with a mean initial weight of 21.0±0.8 kg were randomly distributed in four treatments with ten replicates. The animals were slaughtered after 66 days of confinement. The effects of crude glycerin as a replacement for corn in the diet of the lambs on the carcass characteristics, commercial cut weight and yield and carcass measurements were studied. Results: There was an increasing linear effect for body weight at slaughter with the replacement of corn by crude glycerin. The dry matter and metabolizable energy intakes, weight of the empty body, hot carcass weight and cold carcass weight showed a quadratic effect, with maximum crude glycerin levels estimated at 10.9%, 9.8%, 10.83%, 11.78%, and 11.35%, respectively. The initial pH was not influenced by the replacement of corn for crude glycerin, while the final pH presented a quadratic effect. The other parameters of the carcass and the weights and yields of commercial cuts were not influenced. There was also no effect of the diets on carcass morphometric measurements, except for the thoracic perimeter and the carcass compactness index, which presented quadratic and linear effects, respectively. Conclusion: Crude glycerin can replace up to 18% of corn because it favours muscle tissue deposition without promoting changes in the main carcass characteristics of lambs.

Nitrous Oxide Emissions from Different N Fertilizer Rates Applied to a Maize Crop under Conventional Tillage in Brazil

Bruno Alves,Segundo Urquiaga,Robert Boddey 한국토양비료학회 2014 한국토양비료학회 학술발표회 초록집 Vol.2014 No.6