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Using Arabidopsis Seedlings to Teach Phototropism And Gravitropism in a K-12 Laboratory Classroom
Akhi Moni,한인섭,박형식 한국현장과학교육학회 2014 현장과학교육 Vol.8 No.3
The purpose of this study was to design a laboratory exerciseof a plant’s response to environmental stimuli, such as light andgravity. Since phototropism and gravitropism are two mainphysiological responses for plants to grow efficiently, alaboratory exercise regarding these tropic responses wasdesigned to help students understand differential responses ofshoots and roots to environmental resources. Phototropism orgravitropism is a convenient way of studying the blue-lightphotoreceptor to induce phototropic response or suppress thegravitropic response, respectively. This laboratory experiencecan enhance students’ motivation to learn science and to thinkcritically and creatively.
Repositioning Vitamin C as a Promising Option to Alleviate Complications associated with COVID-19
Farjana Mithila,Moni Akhi,Sohag Abdullah Al Mamun,Hasan Adeba,Hannan Md. Abdul,Hossain Md. Golzar,UDDIN MD JAMAL 대한감염학회 2020 Infection and Chemotherapy Vol.52 No.4
Vitamin C, also known as L-ascorbic acid, is an essential vitamin with pleiotropic functions, ranging from antioxidant to anti-microbial functions. Evidence suggests that vitamin C acts against inflammation, oxidative stress, autophagy chaos, and immune dysfunction. The ability to activate and enhance the immune system makes this versatile vitamin a prospective therapeutic agent amid the current situation of coronavirus disease 2019 (COVID-19). Being highly effective against the influenza virus, causing the common cold, vitamin C may also function against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and its associated complications. Severe infections need higher doses of the vitamin to compensate for the augmented inflammatory response and metabolic demand that commonly occur during COVID-19. Compelling evidence also suggests that a high dose of vitamin C (1.5 g/kg body weight) in inflammatory conditions can result in effective clinical outcomes and thus can be employed to combat COVID-19. However, further studies are crucial to delineate the mechanism underlying the action of vitamin C against COVID-19. The current review aims to reposition vitamin C as an alternative approach for alleviating COVID-19-associated complications.
Kidney protective potential of lactoferrin: pharmacological insights and therapeutic advances
Md,Sarwar Zahan,Kazi Ahsan Ahmed,Akhi Moni,Alessandra Sinopoli,Hunjoo Ha,Md Jamal Uddin 대한생리학회-대한약리학회 2022 The Korean Journal of Physiology & Pharmacology Vol.26 No.1
Kidney disease is becoming a global public health issue. Acute kidney injury (AKI) and chronic kidney disease (CKD) have serious adverse health outcomes. However, there is no effective therapy to treat these diseases. Lactoferrin (LF), a multi-functional glycoprotein, is protective against various pathophysiological conditions in various disease models. LF shows protective effects against AKI and CKD. LF reduces markers related to inflammation, oxidative stress, apoptosis, and kidney fibrosis, and induces autophagy and mitochondrial biogenesis in the kidney. Although there are no clinical trials of LF to treat kidney disease, several clinical trials and studies on LF-based drug development are ongoing. In this review, we discussed the possible kidney protective mechanisms of LF, as well as the pharmacological and therapeutic advances. The evidence suggests that LF may become a potent pharmacological agent to treat kidney diseases.