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Chaetoglobosin A, an Inhibitor of Bleb Formation on K562 Cells Induced by Phorbol 12,13-Dibutyrate
KO, HACK-RYONG,KIM, BO YEON,AHN, SOON-CHEOL,OH, WON KEUN,KIM, JIN-HEE,LEE, HYUN SUN,KIM, HWAN-MOOK,HAN, SANG-BAE,MHEEN, TAE0ICK,AHN, JONG-SEOG 한국미생물 · 생명공학회 1998 Journal of microbiology and biotechnology Vol.8 No.6
Ahn, Ji Yun,Tae, Hyun-Jin,Cho, Jeong-Hwi,Kim, In Hye,Ahn, Ji Hyeon,Park, Joon Ha,Kim, Dong Won,Cho, Jun Hwi,Won, Moo-Ho,Hong, Seongkweon,Lee, Jae-Chul,Seo, Jeong Yeol Medknow PublicationsMedia Pvt Ltd 2015 Neural regeneration research Vol.10 No.8
<P>c-Fos is a good biological marker for detecting the pathogenesis of central nervous system disorders. Few studies are reported on the change in myocardial infarction-induced c-Fos expression in the paralimbic regions. Thus, in this study, we investigated the changes in c-Fos expression in the rat cingulate and piriform cortices after myocardial infarction. Neuronal degeneration in cingulate and piriform cortices after myocardial infarction was detected using cresyl violet staining, NeuN immunohistochemistry and Fluoro-Jade B histofluorescence staining. c-Fos-immunoreactive cells were observed in cingulate and piriform cortices at 3 days after myocardial infarction and peaked at 7 and 14 days after myocardial infarction. But they were hardly observed at 56 days after myocardial infarction. The chronological change of c-Fos expression determined by western blot analysis was basically the same as that of c-Fos immunoreactivity. These results indicate that myocardial infarction can cause the chronological change of immediate-early response gene c-Fos protein expression, which might be associated with the neural activity induced by myocardial infarction.</P>
( Won Tae Kim ),( Kang Moon Seo ),( Yeo Sung Yoon ),( Jae Hoon Kim ),( Jung Hee Yoon ),( Man Bok Jeong ),( Sun Shin Yi ),( Shin Ae Park ),( Hyung Gun Kim ),( Jeong Taek Ahn ),( Chull Gyu Park ) 한국응용약물학회 2010 Biomolecules & Therapeutics(구 응용약물학회지) Vol.18 No.4
The objective of the present study was to evaluate the effect of a mixed extract of three herbs, Panax Notoginseng, Rehmanniae Radix and Acanthopanacis cortex (AIF), for the treatment of horses with experimentally induced osteoarthritis. Twelve healthy male horses were included in this study. Horses were assigned to one of two groups: the AIF group (n=6) or the control group (n=6). Osteoarthritis was induced in all horses by intraarticular injection of sodium monoiodoacetate (0.12 mg/kg). Horses in the AIF group received 3 g of AIF with food daily, and those in the control group received food only. Treatment began on the day of intraarticular injection. Clinical and radiographic evaluations were performed every 2 weeks. At week 12, horses were euthanatized, and postmortem gross pathologic and histologic examinations of the middle carpal joint were performed. There were no significant differences in clinical values between the two groups. Radiographic evaluation revealed that the percentages of narrowness of joint space width in the control group were significantly higher than those in the AIF group (p<0.02). On gross pathologic examination, the mean total dimensions of articular cartilage erosions and fibrillations in the control group (101.5±41.5 mm²) were significantly wider than those in the AIF group (29.3±39.7 mm²; p<0.01). On histopathologic evaluation, significantly higher grades of staining intensity and lower empty lacunae (EL) ratios were found in the AIF group (p<0.03). The present study revealed that AIF had significant disease modifying effects in horses with experimentally induced osteoarthritis.
Won Sik Choi,Seok Woo Nam,Eun Kyung Ahn,Byeoung Soo Park,Sung Eun Lee,Tae Jun Kim,In Young Choi 한국응용생명화학회 2010 Applied Biological Chemistry (Appl Biol Chem) Vol.53 No.2
The fungicidal activities against phytopathogenic fungi of two aminothiazole compounds of N-[4-(4-fluoro)phenyl-2-aminothiazol-5-yl]pyrimidin-2-yl-N-subst. phenylamine (V-1, V-2) have been determined and these two compounds were used as the leading compoun
General perioperative management of gastric cancer patients at high-volume centers
Ahn, Hye Seong,Yook, Jeong Hwan,Park, Cho Hyun,Park, Young Kyu,Yu, Wansik,Lee, Moon-Soo,Sang-Uk, Han,Ryu, Keun Won,Sohn, Tae Sung,Kim, Hyung-Ho,Choi, Seung Ho,Noh, Sung Hoon,Hiki, Naoki,Sano, Takeshi Springer-Verlag 2011 Gastric cancer Vol.14 No.2
A Note on Intuitionistic Fuzzy Subgroups
Tae-Chon Ahn(안태천),Kyung-Won Jang(장경원),Seok-Beom Roh(노석범),Kul Hur(허걸) 한국지능시스템학회 2005 한국지능시스템학회 학술발표 논문집 Vol.15 No.2
In this paper, We discuss various types of sublattice of the lattice of intuitionistic fuzzy subgroups of a given group. We prove that a special class of intuitionistic fuzzy normal subgroups constitutes a modular sub lattice of the lattice of intuitionistic fuzzy subgroups. Moreover, we exhibit the relationship of the sublattices of the lattice of intuitionistic fuzzy subgroups.
A Study on PFC of Active Clamp ZVS Flyback Converter
Tae-Young Choi,Jeong-Joon Ahn,Dong-Kyun Ryu,Woo-Suk Lee,Chung-Yuen Won,Soo-Seok Kim 전력전자학회 2001 ICPE(ISPE)논문집 Vol.2001 No.10
This paper analyzed PFC of active clamp ZVS flyback converter by adding two methods PFC (Power Factor Correction) circuit - two-stage and single-stage. The addition of active clamp circuit also provides a mechanism for achieving ZVS of both the primary and auxiliary switches ZVS also limits the turn off di/dt of the output rectifier, reducing rectifier-switching loss and switching noise, due to diode reverse recovery<br/> As a result, the proposed converters have characteristics of the reduced switching noise and high efficiency in comparison to conventional flyback converter<br/> The simulation and experimental results show that the proposed converter improve the input PF of 300W ZVS flyback converter by adding single-stage, two-stage PFC circuit.<br/>
Age-dependent decrease of Nurr1 protein expression in the gerbil hippocampus
Ahn, Ji Hyeon,Lee, Joon Seok,Cho, Jun Hwi,Park, Joon Ha,Lee, Tae-Kyeong,Song, Minah,Kim, Hyunjung,Kang, Seok Hoon,Won, Moo-Ho,Lee, Choong Hyun D.A. Spandidos 2018 Biomedical reports Vol.8 No.6
<P>Nuclear receptor related-1 protein (Nurr1) serves important roles in hippocampal-dependent cognitive process. In the present study, the protein expression of Nurr1 was compared in the hippocampi of young [postnatal month 3 (PM 3)], adult (PM 12) and aged (PM 24) gerbils using western blot analysis and immunohistochemistry. Results indicated that the protein level of Nurr1 was significantly and gradually decreased in the gerbil hippocampus with increasing age. In addition, strong Nurr1 immunoreactivity was primarily observed in pyramidal neurons and granule cells of the hippocampus in the young group, which was determined to be reduced in the adult group and to a greater extent in the aged group. Collectively the data demonstrated that Nurr1 immunoreactivity was gradually and markedly decreased during normal aging. These results indicate that gradual decrease of Nurr1 expression in the hippocampus may be associated with the normal aging process and a decline in hippocampus-dependent cognitive function.</P>