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안의수,손태열,안응남,김완수,이한,김향선,김동제,김현태,장동현,이상은,정영숙,강지윤 한국운동영양학회 2000 Physical Activity and Nutrition (Phys Act Nutr) Vol.4 No.2
The purpose of this study was to discuss on the preceding studies that is related to bring about the fatigue during submaximal exercise, to make propose an alternative plan on the suppression of blood lactate and ammonia concentration. In general, the fatigue is gave a definition that does not give full play or maintain one's force and power. The fatigue is classified into the central fatigue and peripheral fatigue. There is a controversy on the fatigue that is caused by the center or periphery so far. The discussion on the preceding studies proved the methods of inhibition of the increase in lactate and ammonia during submaximal exercise. We meditated that OKG administration is an effective method to decrease lactate and ammonia by increasing the concentration of glutamate in human body. In other words, we have observed that OKG administration prior to submaximal exercise can improve the exercise capacity and the rate of recovery after exercise.
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발레 동작 시 Ornithine α - ketoglutarate 섭취가 혈중 젖산 , 암모니아 농도 및 효소 활성도에 미치는 효과
이상은,김현태,김완수,이한,안응남,김향선,장동현,안의수,손태열,김동제,정영숙,강지윤 한국운동과학회 2000 운동과학 Vol.9 No.2
발레 동작 시 Ornithine α-ketoglutarate 섭취가 혈중 젖산, 암모니아 농도 및 효소 활성도에 미치는 효과. 운동과학, 제9권 제2호, 289-298, 2000. 본 연구의 목적은 OKG 섭취가 발레 작품 수행 시 증가되는 혈중 젖산과 암모니아 농도 및 그 대사과정에 영향을 주는 요인들에 미치는 효과를 규명하는데 있다. 연구대상은 남자 발레 전공자 6명이었으며, 본 실험 전 최대운동부하테스트를 실시하였다. 본 실험은 1주일 간격으로 위약 섭취 실험과 OKG 섭취 실험으로 2차에 걸쳐 실시하여 다음과 같은 결과들을 얻을 수 있었다. 첫째, 혈중 젖산 및 암모니아 농도 OKG와 섭취 위약 섭취간의 유의한 차이가 나타났다(P<.01). 둘째, 혈중 ALT 및 LDH 활성도는 OKG 섭취와 위약 섭취간의 유의한 차이는 나타나지 않았으나, ALT 활성도는 무용 직전(OKG 섭취 후 50분)부터 회복기 27분까지 OKG를 섭취했을 때가 높은 경향을 보였다. 셋째, 혈중 글루타메이트, 글루타민, 오르니친, 알라닌 농도에 유의한 차이는 나타나지 않았으나 OKG를 섭취했을 때가 높은 경향을 보였다. 결론적으로, OKG 섭취는 고강도의 짧은 발레 작품 수행 후 효소 활성도와 그와 관련된 아미노산에 영향을 미쳐 젖산과 암모니아 생성량을 감소시켜 결국 피로를 줄이고 무용수행 능력 향상에 효과적인 것으로 사료된다. Effects of ornithine α-ketoglutarate administration on blood lactate, ammonia, amino acid concentration and ALT, LDH activity during solo ballet part. Exercise Science, 9(2): 289-298, 2000. The purpose of this study was to investigate the effect of OKG administration on the blood lactate and ammonia that increased during perform in ballet and their metabloism. 6 male ballerinos were participated in the maximal exercise test with treadmill, and the main experiment was executed placebo and OKG at 1 week interval. First, OKG group in the blood lactate and ammonia concentration were significantly lower than placebo group(p<.01). Second, there was no significant difference between the OKG group and placebo group in the blood ALT activity and LDH activity. But, the OKG group in the blood ALT activity was showed the tendency to elevated from pre-dance(after 50 minutes OKG administration) to recovery 20 minutes. Third, OKG group in the blood glutamate, glutamine, omithine and alanine concentration were showed the tendency to elevated. In conclusion, OKG administraion was influenced the enzyme activity and the amino acid connected with it to decreased blood lactate and ammonia. Therefore, we think that, OKG administration is effected to reduce fatigue and to elevated dance performance.
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김현태,이한,김완수,김동제,안의수,안응남,손태열 한국운동영양학회 2001 Physical Activity and Nutrition (Phys Act Nutr) Vol.5 No.1
Carnitine is synthesized in mammals with lysine and methionine providing the carbon backbone of the molecule. Dietary carnitine also contribute to the cannitne-pool in man, but endogenous biosynthetic capacity is adequate to meet body requirments under normal conditions. As muscle does not contain the enzyme for the terminal steps in carnitine biosynthesis, muscle carnitine is derived from diet or synthesis by the liver or kidney. Carnitine is transported to the muscle in plasma, and enters the muscle via an active transport system. Recently it has been shown that L-carnitine in transport of Acyl-CoA through the inner mitochondrial membrane, which activating of β-oxidation in long-chain fatty acids, induce of glycogen sparing effect, known as enhanced exercise and regularly training. Actually, L-carnitine is not consistent of applied exercise situation. Therefore, we think that exercise performance and L-carnitne administration is need to study ahead of a lateral face in multiple.
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