Trichophyton rubrum에 의해 손톱에 발생한 백색 표재성 조갑진균증

안규중 (Kyu Joong Ahn) 대한피부과학회 1994 대한피부과학회지 Vol.32 No.5

Clinical types of onychorpycosis, consist of distal subungual orychomycosis, white superficial onychomycosis, proximal subongual onychomycosis and candidal onychomycosis. White superficial onychomycosis aippears as white, sharply outlined areas on the surfaces of toenails. The fingernails are not affected. Trichophyton mentogrophytes, rarely Trichophyton rubrm, is the causa ive dermatophytes. The auther reports a case of white superficial onychomycosis of the fingernail caused by T. rubrm. (Kor J Dermatol 1804;32(5) 931-933)

단세포군 항체를 이용한 건선환자 말초혈액 T 임파구 및 T 아형의 정량적 측정에 관한 연구

안규중(Kyu Joong Ahn),윤재일(Jai Il Youn),이유신(Yoo Shin Lee) 대한피부과학회 1985 대한피부과학회지 Vol.23 No.5

The study was undertaken to clarify any quantitative abnormalities in peripheral blood T lymphocytes and T subsets, mediating cell meliated immunity, and the presence of any relation between the degree of quantitative abnormalities and extent of skin lesions and activity of disease in patients with psoriasis by monoclonal antibodies. The results were as follows. 1. Mean percentages of total and suppressor T lymphocytes in 39 patients with psoriasis are significantly decreased as compared with those in 32 controls. Mean ratio of percentage of helper T lymphocytes to that of suppressor Tlymphocytes in 39 patients with psoriasis are significantly increased as compared with that in 32 controls. 2, As classified into three groups according to extent of skin lesions (E: less than 5% E,: 5-30%, and E,: more than 30%), mean pereentages of total T lymphocytes in E, and E, psoriasis group and those of suppressor T lymphocytes in all three psoriasi., groups are significantly decreased as compared with those in controIs. Mean percentages of helper T lymphor,ytes in L psoriasis group and mean ratios of percentage of helper T lymphocytes to that of suppressor T lymphocytes in E, and E, psoriasis groups are significantly increased as compared with those in controls. 3. Cis classified into three groups according to activity of disease (A,: stationary, A,: active, peripherally spreading and A,: active, small papules spreading), mean percentage of total T lymphocytes in peripheral blood lymphocytes in A, psoriasis group and those of suppressor T lymphocytes in all three psoriasis group are significantly decreased as compared with those in controls. Mean percentages of helper T lymphocytes and mean ratios of percentage if helper T lymphocytes to that of suppressor T lymphocytes in A, and A, psorixsis groups are significantly increased as compared with those in controls. These results clarified that there are quantitative abnormalities in peripheral blood I' lymphocytes and T subsets in patients with psoriasis and the degrees of abnorrnalities are related to extent of skin lesions and activity of disease. The aanorrnalities in peri.pheral blood T lymphocytes and T subsets in patients with psoriasis seem to be attributed to primary defect of suppressor T lymphoytes.

전풍 병변에서 배양된 Malassezia 균종의 분류

안규중 ( Kyu Joong Ahn ) 대한피부과학회 1997 大韓皮膚科學會誌 Vol.35 No.4

Background: The genus Mulassezia. was recently revised into seven species, M. furfur, M pachydermatis, M sympodialis, M. globosa, M. obtusa, M. restricta and M. slooffiae. Some of the Malassezia species were known to be the etiological agent of pityriasis versicolor. Object: The study was done to place the Malassezia strains cultured from the lesions of pityrisis versicolor into one of The revised species and to elucidate the relationship between certain species and pityriasis versicolor, Methods : The scales from the lesions of twenty cases of pityrisis versicolor were cultured on Leeming & Notmans media. The obtained strains were placed into one of seven species by their colony morphologies, microscopic morphologies and physiological characteristics. Results '. The strains obtained from twenty cases of pityriasis ver sicolor could be placed into one of four species as following incidences. 1 case of M. furfur, 3 cases of M. sympodialis, 15 cases of M globosa, 1 case of M. obtusa, M, globoso occupied the most commonly isolated species cultured from the lesions of pityriasis versicolor. Conclusion : The results suggested that M. globosa could be consider ed as a main etiological agent of pityriasis versicolor among the Malassezia species. (Kor J Dermatol,1997;35(4): 736-743)

Malassezia research in Korea

안규중 ( Kyu Joong Ahn ) 대한피부과학회 2017 대한피부과학회 학술발표대회집 Vol.69 No.2

Symposium 3-4 (SYP 3-4) : Malassezia folliculitis

안규중 ( Kyu Joong Ahn ) 대한피부과학회 2015 대한피부과학회 학술발표대회집 Vol.67 No.1

Histolically, this skin disease was firstly described by Graham (1968) in the discussion of Weary’sarticle. Next year, Weary(1969) also reported acneiform eruption resulting from antibiotic administration. The term ‘ Pityrosporum folliculitis’ was used by Graham (1972) and Potter et al (1973). After Malassezia and Pityrosporum were recognized as the same fungus and Malassezia was accepted as the genus name of both fungi, the term ‘ Malassezia folliculitis’ was introduced by Hanna et al (1983) and Yohn et al (1985). Malassezia folliculitis showed erythematous follicular papules and follicular pustules on the seborrheic body surfaces such as face and upper trunk. Malassezia folliculitis seems to be associated with corticosteroid administration, systemic and/or topical, and also with sweating. Interestingly, Malassezia folliculitis is usually not associated with Pityriasis versicolor, which is mostly caused by Malassezia yeast. Malassezia folliculitis may be confused with true acne, however, can be differenciated from acne by careful examination of skin lesions. The causative species are Malassezia globosa and Malassezia restricta and are closely related with the developed body sites - Malassezia globosa upper trunk, Malassezia restricta head and neck. In this session typical cases of Malassezia folliculitis will be presented. And also several differential points from acne will be briefly guided.

피부 이완증

정환교,안규중,이철현,이종주 ( Hwan Gyo Jeong,Kyu Joong Ahn,Cheol Heon Lee,Chong Ju Lee ) 대한피부과학회 1988 대한피부과학회지 Vol.26 No.2

We experienced a case of cutis laxa in a 17-year-old man. The skin showed diminished elasticity with loose folds, wrinkling, and sagging on the abdomen, lower back, and both inner thighs. There was no history of any inflammatory skit diseases prior to the appearance of the wrinkling. Family history revealed to be negative for the skin diseases showing wrinkling and laxity. The biopsy specimen from the skin of the abdomen showed shortened, fragmented elastic fibers in the dermis. The serum copper level was normal(92 ug/dl).

피지선 모반에서 발생한 피지선 상피종

민형근,안규중,김종민,이일수,이종주 ( Hyung Geun Min,Kyu Joong Ahn,Jong Min Kim,Eil Soo Lee,Chong Ju Lee ) 대한피부과학회 1991 대한피부과학회지 Vol.29 No.3

두피에 발생한 혈관육종

조희진,정환교,안규중,이철헌,이종주 ( Hee Jin Cho,Hwan Gyo Chung,Kyu Joong Ahn,Cheol Heon Lee,Chong Ju Lee ) 대한피부과학회 1988 대한피부과학회지 Vol.26 No.2

Angiosarcoma is a rare malignant vascular tumor of endothelial cell origin. Most lesions of cutaneous angiosarcoma occur over the face and scalp. We experienced a case of angiosarcoma of the scalp in a 63-year-old man. Multiple pea-sized erythematous papules and nodules developed on the forehead 6 months ago. Thereafter, the lesions have extended to make violaceous, compressible and hemorrhagic plaques. On histologic examination, there were irregular, often anastomosing vascular channels lined by the atypical endothelial cells in the dermis.

노년층의 피부 건강 및 피부 질환의 인식에 대한 분석

김민중 ( Min Joong Kim ),손호찬 ( Ho Chan Son ),유박린 ( Bark Lynn Lew ),심우영 ( Woo Young Sim ),이준영 ( Jun Young Lee ),안규중 ( Kyu Joong Ahn ),송해준 ( Hae Jun Song ),김규한 ( Kyu Han Kim ),조광현 ( Kwang Hyun Cho ),이은소 ( 대한피부과학회 2011 대한피부과학회지 Vol.49 No.2

Background: With the development of medical science and technology, the proportion of the aged in the population has significantly increased. For the same reasons, concerns regarding skin aging and skin diseases in the geriatric population has increased. Objective: To evaluate the recognition of skin health and disease in the elderly. Methods: On April 2009, 190 elderly persons were asked to complete a questionnaire in 5 senior welfare centers in the city of in Korea. The questions included: satisfaction with the subject`s own skin; treatment-seeking behavior; knowledge and common sense about representative skin problems; efforts taken to achieve healthy skin. Results: Among the elderly, 44.74% were dissatisfied with their own skin. The most complained about skin diseases in the elderly were pruritus and xerosis. Also, interest in esthetic problems such as wrinkles and pigmentation was high. On the question of whether they visit a dermatologic clinic when they develop skin problems, 40.53% of subjects said that they visited the dermatologic clinic. However, this means that 59.47% did not visit a dermatologic clinic. A somewhat unexpected finding was that knowledge of skin diseases and esthetic problems were plentiful in the geriatric population. Among the elderly, 81.05% did something to achieve skin health such as using a moisturizer or sunscreen. Conclusion: The present study contributes to our understanding of the recognition of dermatologic problems in the geriatric populations. Dermatologists and society should pay more attention to the provision of correct information and appropriate treatments for skin diseases in the elderly. (Korean J Dermatol 2011; 49(2):141~146)

피부종양 2205예에 대한 통계적 관찰

김광수(Kwang Soo Kim),안규중(Kyu Joong Ahn),이철헌(Cheol Heon Lee) 대한피부과학회 1990 大韓皮膚科學會誌 Vol.28 No.6

A statistical study was done on 2205 skin tumors filed at Department of Clinical Pathology, Han Kang and Kang Nam Sacred Heart Hospital during last 10 years from 1980 to 1989. The results were summarized as follows : 1. The number of skin tumor surveyed was 2205 among total 67931 biopsy specimens, 2052 benign skin tumors, 153 malignant tumors. 2. The specimens were requested from the Department of Surgery(707 cases, 32.1 %), Dermatology(618 cases, 28.0%), Plastic Surgery(354 cases, 15.79o), and Or thopedic Surgery(223 cases, 10.1% ). 3. Among 2052 benign skin tumors, the frequently observed tumors were epidermal cyst(577 cases, 28.1%), lipoma(398 cases, 19.4%), melanocytic nevus(121 cases, 5.9 %), dermatofibroma(74 cases, 3.6%), cavernous hemangioma(72 cases, 3.5%), ea.ch of pilmatricoma and neurofibroma(63 cases, 3.1% ), granuloma pyogenicum(57 cases, 2.8%), neurilemmoma(53 cases, 2.6%), seborrheic keratosis(45 cases, 2.2%), soft fibroma(45 cases, 2.2%). 4. Among 153 malignant tumors, the frequently observed tumors were squamaus cell carcinoma(50 cases, 32.7%), basal cell carcinoma(45 cases, 29.4%), malignant melanoma(8 cases, 5.2%), Bowens disease(7 cases, 4.6%), metastatic skin tumors(7 cases, 4.6%) in order. Male to female ratio of malignant tumors was 1.6:1 and the peak age incidence was in 6th decade. 5. Male to female ratio of squamous cell carcinoma was 3.2:1 and of basal cell carcinoma 1: 1.3. The peak age incidences of both squamous cell carcinoma and basal cell carcinoma were 6th decade. The predilection sites of squmous cell carcinoma were face, neck and genitalia and those of basal cell carcinoma were face, lower extremities, neck and trunk. (Kor J Dermatol 28(6):737 746, 1900)