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      • KCI등재

        Newly recorded diatom species in marine and fresh water of Korea

        이진환,박준상 한국생태학회 2015 Journal of Ecology and Environment Vol.38 No.4

        A study on indigenous diatoms was carried out at 71 sites during the period from April 1999 to August 2014 in marine and fresh water in Korea. Forty species of diatoms are new to Korea and they are divided into three classes, six subclasses, 13 orders, 19 families, and 28 genera. The nomenclatures, references, dimensions, specimens examined, local habitat, distribution in Korea, and photograph are reported here. The 40 species found in marine and fresh water showed speciesspecific habitats.

      • KCI등재

        Effects of Roasting on the Phytochemical Contents and Antioxidant Activities of Korean Soybean (Glycine max L. Merrill) Cultivars

        이진환,황정은,이병원,김현태,고종민,백인열,안민주,이희율,조계만 한국식품과학회 2015 Food Science and Biotechnology Vol.24 No.5

        Antioxidant activities of roasted soybeans from Daewon, Daepung, Neulchan, and Taekwang cultivars were evaluated using DPPH and ABTS radical scavenging activities and FRAP assays. Roasted soybeans exhibited significantly (p<0.05) higher antioxidant activities than unroasted soybeans. Daepung soybeans roasted at 200℃ for 15min exhibited higher antioxidant activities than other cultivars and soybeans roasted under other conditions. Contents of antioxidant compounds, including isoflavone aglycones, glycosides, and phenolic acids, increased after roasting, whereas the content of isoflavone malonlyglycosides was decreased in the roasted soybeans. Moreover, total phenolic and flavonoid contents and isoflavone aglycone, glycoside, and phenolic acid contents were increased, leading to a general increase in antioxidant activities due to roasting.

      • KCI등재

        Induction of the unfolded protein response and cell death pathway in Alzheimer's disease, but not in aged Tg2576 mice

        이진환,Sun Joo Son,곽병주,Sun Mi Won,Jaehong Suh,Gyeong Joon Moon,Ui-Jin Park 생화학분자생물학회 2010 Experimental and molecular medicine Vol.42 No.5

        The endoplasmic reticulum (ER) stress results from disrupted protein folding triggered by protein mutation or oxidation, reduced proteasome activity, and altered Ca2+ homeostasis. ER stress is accompanied by activation of the unfolded protein response (UPR) and cell death pathway. We examined if the UPR and cell death pathway would be activated in Alzheimer's disease (AD). RT-PCR experiments revealed increased splicing of X-box binding protein-1 (XBP-1), an UPR transcription factor, in AD compared with age-matched control. Among target genes of XBP-1, expression of protein disulfide isomerase (PDI), but not glucose-regulated protein 78 (GRP78), was increased in AD, suggesting disturbed activation of the UPR in AD. C/EBP homologous protein (CHOP), caspase-3, caspase-4, and caspase-12, downstream mediators of cell death pathway, were activated in AD. Neither the UPR nor cell death pathway was induced in aged Tg2576mice, a transgenic mouse model of Alzheimer's disease that reveals both plaque pathology and some cognitive deficits. The present study suggests that disturbed induction of the UPR and activation of the pro-apoptotic proteins contribute to neuropathological process in AD irrespective of amyloid β and senile plaque.

      • KCI등재

        신임공무원의 성격특성이 학업소진에 미치는 영향에 대한 연구

        이진환 대한산업경영학회 2022 산업융합연구 Vol.20 No.8

        Public officials are volunteers for the people, and the police are in charge of the safety of the people. In particular, the marine safety of Korea, which has three sides of the sea, is very important. The education of maritime police is a very important factor due to the specificity and risk of the sea. In particular, since the new curriculum is linked to the job while in office, factors related to educational performance are more important. In this study, the relationship between personality characteristics and academic burnout was examined for 200 new maritime police officials. Among the five factors of personality characteristics, extroversion factors, neurotic factors, and emotional exhaustion factors were extroversion factors, neurotic factors, and cynicism factors, and extroversion factors, neurotic factors, and integrity factors. In particular, the five factors of personality characteristics that have the greatest influence on academic burnout were neurotic. For the educational satisfaction and effectiveness of the new maritime police officer, it is necessary to minimize the psychological margin and stress of the new maritime police officer. 공무원은 국민의 봉사자로서 국민의 안전은 경찰이 담당하고 있다. 특히 3면이 바다인 우리나라의 해양 안전은 매우 중요하다. 해양이라는 특수성과 위험성으로 인해 해양경찰의 교육은 매우 중요한 요소이다. 특히 신임 교육 과정은 재직하는 동안 직무와 연결되기 때문에 교육 성과와 관련이 있는 요소는 더욱 중요하다. 이 연구에서는 신임해양경찰공무원 200명을 대상으로 성격특성과 학업소진의 관계를 살펴보았다. 연구 결과 성격특성 5요인 중 신체적 고갈에 영향을 미친 요인은 외향성 요인, 신경성 요인, 정서적 고갈에 영향을 미친 요인은 외향성 요인, 신경성, 냉소주의에 영향을 미친 요인은 신경성과 개방성 요인, 성취감 저하에 영향을 미친 요인은 외향성 요인, 신경성 요인, 성실성 요인이었다. 특히 학업소진에 가장 큰 영향을 미치는 성격특성 5요인은 신경성으로 나타났다. 신임해양경찰공무원의 교육적 만족과 효과를 위해서는 신임해양경찰공무원의 심리적 여유와 스트레스 최소화 방안이 필요하다.

      • KCI등재

        Gram-negative Septicemia after Infliximab Treatment in an Infant with Refractory Kawasaki Disease

        이진환,윤정민,임재우,고경옥,천은정 대한소아감염학회 2014 Pediatric Infection and Vaccine Vol.21 No.3

        Kawasaki disease (KD) is an immune-mediated disease which is a leading cause of acquired cardiovascular disease in developed country. Recently, tumor necrosis factor-alpha (TNF-alpha) blocker, infliximab has been considered a promising option for patients with refractory KD. Although chronic use of a TNF-alpha blocker could increase risk of opportunistic infections, a few studies have documented that use of infliximab was safe without serious adverse effects in patients with KD. We observed serious bacterial infection after infliximab treatment in an infant with refractory KD. Our patient was a 5-month-old male infant diagnosed with KD who did not respond to repeated doses of intravenous immunoglobulin. We effectively treated him with a single infusion of infliximab (5 mg/kg), but gram-negative (Acinetobacter lwoffii) septicemia developed after infliximab infusion. Therefore, we report a case of serious septicemia after treatment with infliximab, and suggest considering the risk of severe infection when deciding whether to prescribe infliximab to an infant with refractory KD.

      • KCI등재
      • KCI등재

        한강하류의 환경학적 연구 -VII. 식물플랑크톤군집의 장기간 변화와 전망-

        이진환,정승원,Lee, Jin-Hwan,Jung, Seung-Won 한국조류학회(藻類) 2004 ALGAE Vol.19 No.4

        The literature review on the dynamics of the phytoplankton communities in terms of species composition, standing crops, abundant species and dominant species in the lower part of the Han River from 1940s to 2000s was conducted for the prospective prediction of their succession patterns. Total of 326 taxa were identified and they belonged to 47 blue-green algae, 139 green algae, 12 euglenoids, 126 diatoms, 6 din flagellates and 2 silicoflagellates. Composition of phytoplankton communities were 83.6% diatoms, 10.5% blue-green algae and 5.3% green algae in the middle of 1960s, whereas those were 43.2% diatoms, 40.7% green algae and 13.6% blue-green algae in the 1990s. Before 1990s, Synedra ulna, Melosira varians, Cymbella tumida, Synedra acus, Cymbella ventricosa, Navicula cryptocephala, Nitzschia palea, Aulacoseira granulata, Gomphonema parvulum and Cymbella affinis were most frequent, while those after 1990 were Asterionella formosa, Asterionella gracillima, Aulacoseira granulate, Aulacoseira granulata var. angustissima, Chlorella vulgare, Fragilaria crotonensis and Synedra ulna. Phytoplankton blooms were frequent from winter to the late spring and rare in summer due to heavy rain and discharge. Seasonal variations of the dominant species were fairly obvious; Asterionella gracillima and Aulacoseira granulata in spring, Aulacoseira granulate and Aulacoseira granulate var. angustissima in summer and autumn, Asterionella gracillima and Stephan discus hantzschii in winter. Recently blue-green algae, Microcystis, Aphanocapsa, Dactylococcopsis have been more abundant than those of the previous reports. Based on the current situations, Stephan discus hantzschii f. tennis, Asterionella gracillima, Aulacoseira granulate and blue-green algae will be more abundant and blooms of those species will be more frequent.

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