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이세영,김승회,이윤영,구양모,Se Young Lee,Seung Hoi Kim,Youn Young Lee,Yang Mo Goo 대한화학회 1992 대한화학회지 Vol.36 No.2
3-알킬리덴-2,4-펜탄디온(1)과 아릴히드라진을 메탄올에서 반응시키면 4-아세틸(2), 4-(1-메톡시알킬)-(3) 또는 4-비닐피라졸 유도체(4)가 얻어진다. 3-(2,2,2-트리클로로에틸리덴)-2,4-펜탄디온(9)과 아릴히드라진과의 반응에서는 4-아세틸-1-아릴-3-메틸피라졸(11)이 생성된다. 이 반응들의 가능한 메카니즘을 제시하였다. Reaction of 3-alkylidene-2,4-pentanediones(1) with arylhydrazines in methanol afforded 4-acetyl-(2), 4-(1-methoxyalkyl)-(3), or 4-vinylpyrazole derivatives(4). 3-(2,2,2-Trichloroethylidene)-2,4-pentanedione(9) reacted with arylhydrazines to give 4-acetyl-1-aryl-3-methylpyrazoles(11). Possible mechanisms for these reactions were proposed.
두경부암에서 Human Papillomavirus의 검출 방법
이세영 대한이비인후과학회 2012 대한이비인후과학회지 두경부외과학 Vol.55 No.1
Ever since human papillomavirus (HPV) has known to be associated with head and neck cancer, there have been many studies investigating the role of HPV as its causative factor. The most important thing among studies for HPV is to obtain HPV from cancer tissue and find out whether the obtained HPV is related to the development of cancer. However, until now, there has been no standardized method in diagnosing HPV infection. The various detecting methods for HPV and difference in sensitivity among experimental methods are one of the reasons for the controversy over the role of HPV. In this review, we present the advantages and disadvantages of HPV detection methods those are currently used and suggest standardized methods that may be used to detect HPV in head and neck cancer in the future.
회전하는 터빈 블레이드 내부 이차냉각유로에서 엇갈린요철과 평행요철이 열/물질전달에 미치는 영향
이세영,이동호,조형희,Lee, Se-Yeong,Lee, Dong-Ho,Jo, Hyeong-Hui 대한기계학회 2002 大韓機械學會論文集B Vol.26 No.9
The present study investigates the convective heat/mass transfer inside a cooling passage of rotating gas-turbine blades. The rotating duct has various configurations made of ribs with 70。 attack angle, which are attached on leading and trailing surfaces. A naphthalene sublimation technique is employed to determine detailed local heat transfer coefficients using the heat and mass transfer analogy. The present experiments employ two-surface heating conditions in the rotating duct because the surfaces, exposed to hot gas stream, are pressure and suction side surfaces in the middle passages of an actual gas-turbine blade. In the stationary conditions, the parallel rib arrangement presents higher heat/mass transfer characteristics in the first pass, however, these characteristics disappear in the second pass due to the turning effects. In the rotating conditions, the cross rib present less heat/mass transfer discrepancy between the leading and the trailing surfaces in the first pass. In the second pass, the heat/mass transfer characteristics are much more complex due to the combined effects of the angled ribs, the sharp fuming and the rotation.