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방찬일 ( Chan Yl Bang ),변지원 ( Ji Won Byun ),신정현 ( Jeong Hyun Shin ),황승식 ( Seung Sik Hwang ),최광성 ( Gwang Seong Choi ) 대한피부과학회 2013 대한피부과학회지 Vol.51 No.12
Background: Female pattern hair loss (FPHL) is the most common type of pattern hair loss in women. It has been suggested that FPHL is associated with several serological abnormalities. Objective: The aim of this study is to investigate the clinical characteristics and serological abnormalities of the Korean FPHL patients and to compare them with the data from the Korea National Health and Nutrition Examination Survey V and other relative reports. Methods: We retrospectively evaluated the age, duration and comorbidities in 264 Korean patients who have been diagnosed with FPHL. Serum levels of serum iron, total iron binding capacity, ferritin, hemoglobin, free thyroxine (T4), thyroid stimulating hormone, testosterone and 25-(OH) vitamin D were being investigated. Results: FPHL was most commonly found in patients aged from 20 to 29 years old and 55% of the patients visited the hospital one year after the onset of FPHL. In FPHL patients, the levels of testosterone, hemoglobin, serum ferritin, 25-(OH) vitamin D, thyroid stimulating hormone were all significantly higher than the average Korean adult women. And, the free thyroxine level was significantly lower than the average Korean adult women. When analyzed according to the menopausal status, premenopausal FPHL patients showed significantly higher serum levels of hemoglobin, ferritin, and 25-(OH) vitamin D than those of the Korean adult women. But, the postmenopausal FPHL patients showed significantly higher serum levels of 25-(OH) vitamin D than those of Korean adult women. Conclusion: The levels of ferritin, testosterone and vitamin D of FPHL patients were elevated higher than those of the Korean adult women. To confirm these results in the future, further large scaled evaluation is suggested.
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강민지 ( Min Ji Kang ),변지원 ( Ji Won Byun ),신정현 ( Jeong Hyun Shin ),황승식 ( Seung Sik Hwang ),최광성 ( Gwang Seong Choi ) 대한피부과학회 2013 대한피부과학회지 Vol.51 No.11
Background: Androgenetic alopecia (AGA) is the most common type of hair loss, and androgens and genetic predisposition are believed to be the major factors that influence the development of AGA. Although there have been previous reports about the relationship between family history, smoking and insulin resistance with AGA, no previous study has investigated lifestyle habits such as eating habits in AGA patients Objective: The aim of this study was to investigate family history, lifestyle including smoking and eating habits in AGA patients and to compare the results with data from Korea Health Statistics 2009: Korea National Health and Nutrition Examination Survey (KNHANESIV-3). Methods: We retrospectively evaluated a total of 347 male patients with AGA who visited the Department of dermatology, Inha University School of medicine, from September 2010 to August 2012. Results: AGA with paternal family history was the most common (49.9%), and both of maternal and paternal family history was the least (10.1%). Body mass index and smoking did not show significant differences but eating habits showed a statistically significant difference according to the duration of AGA. Patients with longer disease duration (≥60 months) showed higher intake of meat but low intake of fish than those with shorter disease duration (<12 months). Also, AGA patients showed low intake of beef, bean and squid in comparison to the average Korean population. Conclusion: This was the first study which investigated lifestyle habits such as eating habits in AGA patients and compared the results with data from Korea Health Statistics. However, a further large scale Cohort study is needed to define the casual relationship between eating habits and the development of AGA. Also, a further study including the difference of serum and hair androgen levels in relation to different lifestyle habits should be done. (Korean J Dermatol 2013;51(11):878∼884)
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