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이미화,박기현,송지홍,조동제,황동훈,송찬호,Lee, M.H.,Park, K.H.,Song, J.H.,Cho, D.J.,Hwang, D.H.,Song, C.H. 대한생식의학회 1994 Clinical and Experimental Reproductive Medicine Vol.21 No.3
In order to define the clinical characteristics of Korean women with polycystic ovary syndrome, clinical symptoms, biochemical features and ultrasonographic findings were determined in ninety PCO patients. Frequency of clinical manifestations were as follows:acne 42%, overweight 31 %, oily skin 14 %, hirsutism 10%. Relatively low frequencies of hirsutism is recognized in patients with Korean PCO syndrome. Mean(${\pm}$S.E.) of each hormone was:testosterone 1.18${\pm}$1.07ng/ml, LH 21.47${\pm}$${\pm}$2.6mIU/ml, FSH 7.26${\pm}$2.67mIU/ml, LH/FSH ratio 2.94${\pm}$1.29, prolactin 25.48${\pm}$46.33ng/ml, DHEA-S 333.78${\pm}$309.60ng/dl, 17-0HP 1.72${\pm}$1.74ng/ml. Mean 17-OHP after ACTH stimulation test was 5.07${\pm}$12.01ng/ml. Ultrasonographically measured mean ovarian volume were $11.02{\pm}5.92cm^3$ in right and $9.23{\pm}5.64cm^3$ in left and small sized multiple subcapsular follicular cysts were noted in 43 patients (47.9%) with PCO syndrome.
불임환자의 세척정자에 의한 자궁내 인공수정의 임상적 평가
이승헌,윤영욱,이보연,이병석,박기현,황동훈,Lee, S.H.,Yoon, Y.W.,Lee, B.Y.,Lee, B.S.,Park, K.H.,Hwang, D.H. 대한생식의학회 1992 Clinical and Experimental Reproductive Medicine Vol.19 No.1
The sucess of intrauterine inseminations with washed human spermatozoa was evaluated in 92 patients. In according to indication of insemination, intrauterine inseminations of women with hostile cervical mucus yield a 35.3% and 12.8% with male factors and 27.3% with unexplained infertility. In ovulation induction group with variable agents including clomiphen, human menopausal gonadotropin (HMG) and GnRH analog, the pregnancy rate was 27.8% (22/79) and in natural cycle group, 15.4% (2/13). The fetal loss rate in insemination group was 12.5% (3/24). Multiple pregnancies were 7 cases and ovulation induction were performed in 6 cases among them. Intrauterine insemination with washed human spermatozoa therefore represents an effective and safe procedure selected infertile couples.
이보연,정미정,박기현,이병석,조동제,황동훈,송찬호 中央醫學社 1992 中央醫學 Vol.57 No.4
To evaluate the clinical effects of transdermal estrogen replacement therapy in postmenopausal women, especially cardiovascular effect by change of serum lipid profiles after the treatment, 32 postmenopausal women - 18 natural menopausal women, 14 women with premature ovarian failure - were studied before and after 6 8 weeks of treatment withE2 containing transdermal therapeutic systems. 1. The postmenopausal symptoms were improved or disappeared in all cases. 2. Significant changes of serum LDL level, HDL/LDL ratio were noted. 3. The side effects of transdermal estrogen replacement therapy were noted with skin eruption (7 cases), vaginal spotting (3 cases) and breast pain (2 cases), but no discontinuation of the treatment was resulted. This study was concluded that the transdermal estrogen replacement therapy was effective on the prevention of cardiovascular diseases in postmenopausal women.