http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
Papanicolaou smear에서 자궁내막암의 세포학적 진단의 의의 : 조직유형, 분화도 및 병기와의 관련성
홍성란,김희숙,박종숙,Hong, Sung-Ran,Kim, Hy-Sook,Park, Jong-Sook 대한세포병리학회 1993 대한세포병리학회지 Vol.4 No.2
The cytologic detection of endometrial carcinoma in Papanicolaou(Pap) smear according to histologic type, grade and stage was studied in 49 patients. The smears of patients who had histologically confirmed were retrospectively evaluated by the Bethesda System. The cytologic diagnosis of endometrial carcinoma was made in 61% (39/49) of patients, atypical glandular cells of undetermined significance (AGCUS) in 16% (8/49) and within normal limits in 23% (11/49). The positive rate for AGCUS and carcinoma was correlated to the histologic type, grade and stage. The cytologic grade revealed a good correlation with histologic grade, too. In conclusion, the presence of cancer cells in Pap smear suggests the tumor in high grade and high stage. Additionally, cytologic detection of AGCUS or carcinoma needs a further diagnostic evaluation. The Pap smear is a valuable method to screen for endometrial carcinoma.
질의 원발성 무색소성 악성흑색종의 세포학적 소견 - 1례 보고 -
홍성란,김희숙,박종택,Hong, Sung-Ran,Kim, Hy-Sook,Park, Chong-Tack 대한세포병리학회 1993 대한세포병리학회지 Vol.4 No.1
A case of primary amelanotic melanoma of the vagina diagnosed in scraping smear is described. A 64-year-old woman complained of vaginal bleeding with a $2.5\times2cm$ sized, fungating mass on the right lateral vaginal wall near the introitus for 2 months. Scraping smears from the mass showed scattered individual tumor cells with single, bi- or multi-nucleated eccentric nuclei having prominent macrouucleoli and occasional intranuclear inclusions. The cytoplasm was plump and cyanophilic with a indistinct rim. No melanin pigment was identified. Characteristic cytologic features of this case were very helpful to exclude more common squamous cell carcinoma in the vagina, which was strongly suggested in biopsy specimen.
만성 림프성 갑상선염과 동반된 갑상선의 악성 림프종 -1예 보고-
홍성란,윤귀옥,김성숙,조혜제,고일향,김홍용 인제대학교 1985 仁濟醫學 Vol.6 No.4
Primary lymphomas of the thyroid occur predominantly in elderly women who present with histories of rapid enlargement of the thyroid gland, often with dysphagia, hoarseness, and symtoms of tracheal compression. Involvement of only one lobe is common. Malignant lymphoma of thyroid has been frequently associated with lymphocytic thyroiditis. Recently we experienced a case of thyroid lymphoma associated with an underlying lymphocytic hyroiditis in 64-year-old female who complained of rapid growing firm, well circumscribed movable mass in anterior neck for 3 months. The thyroid function was within normal limits. Grossly, the entire lobe was nearly replaced by homogeneous white yellow rubbery mass of fish flesh glistening apperance. On light microscopy, it was histologic type of malignant lymphona by the Rappaport classification (high grade, large cell, immunoblastic type by Working formulation; FCC, immunoblastic type by Lukes-Colline classification), associated with chronic lymphocytic thyreiditis. All 14 nodes found in the adjacent tissue are partially or totally replaced by lymphomatous changes.
비정상 자궁경부도말에서 AutoPap 300 QC System의 민감도와 Score에 영향을 주는 인자의 평가
홍성란,Hong, Sung-Ran 대한세포병리학회 1998 대한세포병리학회지 Vol.9 No.2
The AutoPap 300 QC System is an automated device for the analysis and classification of conventional cervical cytology slides for quality control purpose. These studies evaluated the sensitivity of the AutoPap 300 QC System, and estimated morphologic features other than epithelial abnormality to identify a high quality control(QC) score with the AutoPap 300 QC System. The sensitivity of the AutoPap 300 QC System at 10% review rate for 210 cases of cervicovaginal cytology with low grade squamous intraepithelial lesion(LSIL) and higher grade lesion was assessed, and compared with a 10% random rescreening. The morphologic features, such as presence of endocervical component, dirty background, atrophy, abnormal ceil size, and celluiarity of single atypical cells were estimated in 45 cases of no review and 30 cases of QC review cases. The AutoPap 300 QC System identified 119(56.7%) out of 210 cases with LSIL and higher grade lesion at 10% review rate. It was more sensitive to squamous cell lesions$(50{\sim}62%)$ than to glandular lesions(10%). The dirty background and the scanty cellularity of single atypical cells were significantly related to low QC score. Conclusively, AutoPap 300 QC System is superior to human random rescreen for the identification of false negative smears. The upgrading of this device is required to enhance the defection of glandular lesion and certain Inadequate conditions of the slides.
자궁내막증식증의 세포학적 고찰: 정상자궁내막세포 및 자궁내막선암종과 비교
홍성란,선미임,김의정,전이경,김혜선,김희숙,Hong, Sung-Ran,Seon, Mee-Im,Kim, Yee-Jeong,Chun, Yi-Kyeong,Kim, Hye-Sun,Kim, Hy-Sook 대한세포병리학회 2000 대한세포병리학회지 Vol.11 No.1
The purpose of this study is to describe the cellular characteristics of endometrial hyperplasia without/with atypia in cervical smears. These cellular features were compared with those of normal endometrium and endometrial carcinoma. We reviewed 265 cervical smears : 64 normal proliferative endometrium, 118 endometrial hyperplasia without atypia, 21 endometrial hyperplasia with atypia, and 62 endometrial adenocarcinoma. Of these smears, 72(27.2%) smears which had diagnostic endometrial epithelial cells were selected for this study. The cytologic abnormalities about cellularity, background, changes in cellular architecture, alterations in nuclear size, anisokaryosis, chromatin pattern, nucleoli, cytoplasmic vacuoles, and mitosis were observed. Nuclear enlargement(1.6 to 2 times of the nucleus in the intermediate squamous cell) and anisokaryosis(${\geq}$2 fold in size variation) were highly suggestive of endometrial hyperplasia without/with atypia. The nuclei from endometrial hyperplasia with atypia were more coarsely granular in chromatin patterns than hyperplasia without atypia(33.3% vs 3.4%). Micronucleoli were observed in all endometrial conditions, but the presence of macronucleoli were more suggestive of hyperplasia with atypia(22.2%) and adenocarcinoma(55%). The changes in cellular architecture(loss of polarity, uneven internuclear distance, overlapping and loose arrangement) were seen in hyperplasia with atypia and adenocarcinoma. Characteristically, bloody background was seen in endometrial hyperpiasia, and cellular detritus or granular proteinaceous material was only observed in endometrial adenocarcinoma. Mitoses were also observed in adenocarcinoma. In conclusion, although there is no single parameter useful for the cytologic differential diagnosis of endometrial lesions, combined cytologic evaluation can be used to diagnose hyperplasia cytologically.
폐문에 발생한 Giant Lymph Node Hyperplasia의 1예
홍성란,김성숙,백애란,백인기,고일향,이남수,손광현 인제대학교 1985 仁濟醫學 Vol.6 No.1
Giant lymph node hyperplasia의 hyaline vascular type이 우측 폐문에서 발생한 1예를 보고하고자 한다. We experienced a case of the hyaline vascular variant of giant lymph node hyperplasia (Castleman's disease). This lesion was discovered by routine roentgenogram of the chest, and the rigth hilar lymph node was affected, accompanied with hyperplasia of lymph nodes on Para SVC. The hilar mass was surgically removed. Histologically, the nodal architecture was altered by an increased number of lymphoid follicles, which were transfixed by radially penetracting capillaries. Many of these capillaries were ensheathed by collagenous hyalinization. The follicles center cells were generally concentrically layered.