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RISS 인기검색어
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- 저자 : 홍미재(Mi Jae Hong) (검색결과 3 건)
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상부 위장관 질환에 있어 Campylobacter Pyloridis 에 대한 연구
이상종(Sang Jong Lee),이만호(Man Ho Lee),박영철(Young Chul Park),강진호(Jin Ho Kang),정을순(Eul Soon Jung),홍미재(Mi Jae Hong),김유경(You Kyoung Kim) 대한소화기학회 1989 대한소화기학회지 Vol.21 No.1
N/A Since the first description of an unidentified curved bicillus that was called campylobacter pyloridis and isolated from gastric mucosa by Warren and Marshall in 1983 the campylobacter pyloridis has been implicated as a bacteriologic agent for the etiology of gastritis and peptic ulcer. 171 patients with upper gastrointestinal symptoms referred to endoscopic study in our clinic between December 1987 and December 1988, 19 asymtomatic individuals were considered for study. By culture of Warthin-Starry silver stain and gram stain or both, we found that overall 73% (124/171) of patients were positive for compylobacter pyloridis. In other endoscopic groups, the following positive incidence were found: severe superficial gastritis, 76% (67/88): chronic superficial gastritis, 67 %(33/49); gastric ulcer, 81%(9/11): duodenal ulcer, 83%(5j6): gastric cancer 59%(10/17). In various histologic groups, we found the organism in 75%(81/108) of patients among severe superficial gastritis and 59%(10/17) of patients among gastric adenocarcinoma. But in the control group of 19 asymptomatic individuals, the organisms were found from only 5 cases (26%). In its antimicrobial sensitivity test, cephalosporin, chloramphenicol, erythromycin, carbenicillin, kanamycin and tetracycline have the sensitivity of 100%. Amikin, ampicillin and tobramycin were sensitive in 71% to 80% and gentamycin was sensitive in 50%, but colistin was resistant. 12 campylobacter pyloridis positive patients were treated by various therapeutic regimens for 4 weeks (ranitidines, sucralfate: colloidal bismuth substrate: antibiotics). Among the patients, the patients, the histologic improvement was in the group treated with colloidal bismuth substrate. These results support the hypothesis that campylobacter pyloridis might be etiologically related to gastritis and peptic ulcer.
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이만호,고동혁,이상종,정을순,홍미재,임시영,주영만 대한내분비학회 1989 Endocrinology and metabolism Vol.4 No.1
Since the severity of hyperthyroidism is generally not reflected by the magnitude of elevation of values in thyroid function test, it is potentially useful to have a hyperthyroid symptom scale (HSS) to assess the clinical status and the response to various treatments. To evaluate the changes of symptoms in the management of Graves' disease, thyroid function test including T4RIA, Free T3 and TSH, and hyperthyroid symptom scale were administered to three groups of the patients with untreated Graves' disease (Group I), patients with treated Graves' disease (Group II) and normal subjects (Group III). Hyperthyroid symptom scale is a ten item scale that rates nervousness, diaphoresis, heat tolerance, motor activity, tremor, weakness, hyperdynamic precordium, diarrhea, weight loss and appetite, and overall function. And the intencity of each item can be rated on a subsacle from 0 to 4 points. Except normal control group, all patients had the clinical and chemical evidence of graves' disease and had HSS scores of 17 to 29 points, but in normal controls, 4 to 12 points. Both thyroid function tests and HSS scores were significantly reduced after propylthiouracill and tenormin therapy in the treated Graves' disease group. And in normal controls, HSS scores showed less than those of untreated Graves' disease group. We considered that this scale including ten categories of symptoms is sensitive to changes in both the adrenergic and metabolic components of Graves' disease and it is useful in the clinical assessment and management of patients with Graves' disease. (J Kor Soc Endocrinol 4:55-58, 1989)
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채종찬,이만호,고동혁,정을순,김향,이상종,홍미재 대한내과학회 1989 대한내과학회지 Vol.36 No.2
Although embolic occlusion of a renal artery is not rare, correct diagnosis and appropriate treatment are often delayed. We recently experienced in a case of renal artery embolism associated with mitral stenosis 45-year-old male, who suffered from a sudden onset of severe intractable abdominal pain. Analgesics a and sedatives did not alleviate the pain. Pertinent but non-specific laboratory findings disclosed leukocytosis, proteinuria and an increased serum lactic dehydrogenase level. A renal scan showed delayed excretion of the right kidney and a renal arteriogram disclosed abrupt cutting of the segmental artery of the right kidney associated with a filling defect in the delayed phase. He discharged from the hospital against advice for further evaluation and observation of his condition.
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