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Twelve Contiguous Spinous Process Fracture of Cervico-Thoracic Spine
한성록,손문준 대한척추신경외과학회 2014 Neurospine Vol.11 No.3
The clay-shoveler's fracture is an isolated avulsion fracture of the lower cervical or upper thoracic spinous process. Among them, multiple spinous process fractures are very rare. We present 34-year-old male patient who have multiple spinous process fractures with twelve contiguous levels of cervico-thoracic spine (from C4 to T8) after motorcycle accident. This case is multiple isolated spinous process fractures with good clinical outcome.
A Case of Brachial Plexus Neurofibroma
한성록,이기택,최찬영,이채혁 대한척추신경외과학회 2011 Neurospine Vol.8 No.1
Tumors of the brachial plexus are relatively rare. The most common intrinsic tumors involving the brachial plexus are benign schwannomas and neurofibromas. Neurofibromas are usually associated with neurofibromatosis-1 (NF-1). Solitary neurofibromas unassociated with NF-1 are very uncommon. We report a 56 year-old man with brachial plexus solitary neurofibroma and reviews of literatures.
실험적 외상성 뇌손상모델에서 외상 후 저체온과 MgSO<sub>4</sub>의 효과
한성록,현동근,박종운,하영수,김준미,Han, Seong Rok,Hyun, Dong Keun,Park, Chong Oon,Ha, Young Soo,Kim, Joon Mee 대한신경외과학회 2000 Journal of Korean neurosurgical society Vol.29 No.10
Objective : Traumatic brain injury including diffuse axonal injury has been shown to result in a decrease in brainfree magnesium concentration, an endogenous inhibitor of calcium entry into neuron, that is associated with the development of neurological motor deficits. The goal of this study is to establish the therapeutic window during which the therapy with $MgSO_4$ and/or hypothermia improve damaged neurons by TUNEL stain. Method : Moderate brain injury was induced in 64 adult Sprague-Dawley rats, weighing 350 to 450gm each, by using a simple weight-drop device(Marmarou model). The animals were randomly assigned to four groups(sixteen rats each, a control group, a group treated with $MgSO_4$, a group treated with hypothermia, and a group treated with $MgSO_4$ and hypothermia) and the rats in each group were sacrificed and studied after 12 hrs, 24 hrs, 1 wk, and 2 wks after insult. In hypothermic group, these rats were subjected to hypothermia after injury, with their rectal temperatures maintained at $32^{\circ}C$ for 1 hour. After 1-hour period of hypothermia, rewarming to normothermic level was accomplished over 30-minute period. In the groups treated $MgSO_4$, hypothermia and $MgSO_4$ were subsequently treated with $MgSO_4$($750{\mu}moles/kg$) infused intra-muscularly at 30 minutes after trauma. Result : In all treated groups, a significant reduction in TUNEL positive cells was found in comparison with the control group each time(p<0.001). Between treatment groups, No differnce was seen 12hrs, 24hrs, and 1wk. However, hypothermic group treated with or without $MgSO_4$ showed more significant reduction in apoptotic cells than group treated with $MgSO_4$ 2 weeks after trauma(p<0.05). However, hypothermic group treated with $MgSO_4$ showed no significant reduction in apoptotic cells compared with hypothermic group(p>0.05). Conclusion : These findings suggest that both hypothermia and $MgSO_4$ significantly improve pathological changes. Otherwise simultaneously $MgSO_4$ and hypothermia treatment groups is failed to provide additional neuroprotection. These results may be relevant to the design of future clinical trials of therapeutic hypothermia and $MgSO_4$ for traumatic brain injury.
Spontaneous Regression of Cervical Disc Herniation : A Case Report
한성록,최찬영 대한척추신경외과학회 2014 Neurospine Vol.11 No.4
Spontaneous regression of cervical disc herniation is a rare, and such reports are few. A 39 year-old woman complained of severe neck pain associated with tingling and numbness of right upper extremity. The MRI of the cervical spine revealed a posterior disc extrusion at the C4-C5 level in the right para-central location. The patient was treated with conservative management without any surgical treatment. The patient’s symptoms were significant improvement. After two years later, we performed follow-up cervical MRI that revealed significant spontaneous regression of the C4-C5 intervertebral disc extrusion.
한성록 ( Seong Rok Han ),이기택 ( Gi Taek Yee ),윤상원 ( Sang Won Yoon ),손문준 ( Moon Jun Sohn ),황충진 ( Choong Jin Whang ) 대한뇌종양학회 2004 대한뇌종양학회지 Vol.3 No.2
Hemangioblastomas are solid or cystic benign vascular tumors that may arise anywhere in the body. Solid hemangioblastomas can be difficult to treat surgically because of their hypervascularity and reqirement for circumferential dissection. Recently, We experienced a huge solitary solid hemangioblastoma in the cerebellopontine angle. The tumor was safely resected totally. We report the case with review of literatures.
한성록 ( Seong Rok Han ),윤상원 ( Sang Won Yoon ),이기택 ( Gi Taek Yee ),최찬영 ( Chan Young Choi ),손문준 ( Moon Jun Sohn ),이동준 ( Dong Joon Lee ),황충진 ( Choong Jin Whang ) 대한뇌종양학회 2007 대한뇌종양학회지 Vol.6 No.1
Objective:Atypical meningiomas(AMs) are difficult tumors to manage. The authors evaluate local control and survival after primary surgery for patients with AMs. Methods:Of the 108 meningioma patients surgically treated between 2000 and 2005, pathologically proven 10 AMs were reviewed. Mean follow-up periods were 35.9(range, 7-68) months. Results:Four(40%) had local recurrences during the follow-up, of which 1(14%) of 7 gross total removal and 3(100%) of 3 subtotal removal. The mean time to recurrence was 33.8 months. The overall 3-year local control rates were 70%. All patients were survived during follow-up period. Seven(70%) patients were treated Novalis radiosurgery. 3 patients had residual tumors and 4 patients had recurrent tumor. Conclusion:The aim of treatment for AMs is to resect totally as possible. Radiosurgery for remnant or recurrent AMs could be considered as adjuvant therapy, although further study is mandatory.
한성록(Seong Rok Han),윤상원(Sang Won Yoon),이기택(Gi Taek Yee),최찬영(Chan Young Choi),손문준(Moon Jun Sohn),이동준(Dong Joon Lee),황충진(Choong Jin Whang) 대한두개저학회 2006 대한두개저학회지 Vol.1 No.2
Pituitary adenomas are very common neoplasms, constituting between 10 and 20% of all primary brain tumors. Historically, the treatment armamentarium for pituitary adenomas has included medical management, microsurgery, and fractionated radiotherapy. More recently, radiosurgery has emerged as a viable treatment option. We present a case of giant pituitary adenoma, treated two staged microsurgery and Novalis radiosurgery, which managed postoperative remnant pituitary adenoma successfully.
중추 신경계에서 발생한 비정형 기형/횡문근양 종양 -증례보고-
한성록 ( Seong Rok Han ),윤상원 ( Sang Won Yoon ),이기택 ( Gi Taek Yee ),손문준 ( Moon Jun Sohn ),주미 ( Mee Joo ),황충진 ( Choong Jin Whang ) 대한뇌종양학회 2004 대한뇌종양학회지 Vol.3 No.2
Atypical teratoid/Rhabdoid tumors(AT/RT) are aggressive neoplasm that afflict infants and young children and are the new entity among malignant pediatric brain tumors. These tumors show similar histological and radiological features to primitive neuroectodermal tumor-medulloblastoma(PNET-MB). So, these tumors have been misdiagnosed previously as PNET-MB. Separation of these two tumor types is crucial. Because the prognosis of a patient with an AT/RT is worse than that of a PNET-MB despite aggressive surgical treatment with or without adjuvant chemotherapy and radiation therapy. Recently, we experience a 5-month girl with a primary intracranial AT/RT in the posterior fossa. We report the case with a special emphasis on the differential diagnosis from PENT-MB.
유홍진,한성록 순천향대학교 부설 산업기술연구소 2002 순천향 산업기술연구소논문집 Vol.8 No.1
Phenol was separated from wastewater by membrane solvent extraction, using a microporous bydrophobic hollow fiber module. The system was operated counter-currently and cocurrently with the aqueous phase flowing through the fiber lumens and the solvent flowing through the shell side. MIBK was used as an extracting solvent. Separation efficiency of countercurrent flow method was better than that of cocurrent flow method.