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      • KCI등재후보

        위장관림프종의 임상적 고찰

        천종욱(Jong Wook Cheon),송홍석(Hong Suck Song),김인호(In Ho Kim) 대한내과학회 1988 대한내과학회지 Vol.34 No.5

        N/A A retrospective review is presented for 45 previously untreated patients with gastrointestinal lymphoma between January 1972 through September 1987 at the Keimyung University. The mean age was 42.3 years with a male to female ratio of 2.2:1. On admission abdominal pain was the most frequent symptom in 23cases (51.1%) and abdominal mass, fever, weight loss, epigastric pain, diarrhea, general weakness, anorexia were commonly presented. Physical findings revealed abdominal mass in 21cases (46.7%), peripheral lymph node enlargement in 15cases (33.3%) with cervical inguinal axillary in order of frequency. Hepatomegaly was observed in 9cases, ascites in 5cases, pleural effusion in 4cases, intestinal intussusception in 4cases, intestinal perforation in 3cases and intestinal obstruction in 2cases. Gastrointestinal involvement was as follows: small intestine in 24cases, large intestine in 12casese, stomach in 11cases, cecum in 10cases, rectum in 2cases, appendix in 12cases and duodenum in 1case. Laboratory findings revealed anemia in 37,8~%, leukopenin in 8,9%, leukocytosis in 20.0%, lymphopenia in 28.9%, thrombocytopenia in 15.4%, hypoproteinemia in 24.4%, hypoalbuminemia in 57.8%, azotemia in 20.9%, increased alkaline phosphatase in 11.9% and increased SGPT in 16.7%. Histologic classification revealed Hodgkin`s disease in 3cases of all lymphocyte depletion type, non-Hodgkin`s lymphoma in 41cases with 25cases of histiocytic type, 6cases of mixed & poorly differentiated lymphocytic type respectively, and 4cases of well-differentiated lymphocytic type. By Ann Arbor staging, stage I was 6cases (13.3%), stage II 15cases (33.3%), stage III 2cases (4.4%) and stage IV 22cases (48,9%), and B symptom was associated in 24cases (53.3%), Treatment was performed as follows: Radical resection in 18cases, radiotherapy in 2cases, combination chemotherapy in 19cases, combined modality therapy in 2cases, and complete remission was obtained in 12cases (52,2%) among evaluable 23cases. Five year survival rate of 23 treated patients was 60% with statistically very significance between complete remission and partial or no remission group (P<0.005), and no statistical significance between stage A and stage B, loco-regional ~(stage I+II) and advanced stage (stage III+IV).

      • KCI등재후보

        소화성 궤양의 발생빈도와 위궤양의 연령별 호발부위

        허정욱,이수형,안성훈,박승국,천종욱,강영우 啓明大學校 醫科大學 1987 계명의대학술지 Vol.6 No.2

        Clinical analysis was performed on 1582 cases of peptic ulcer patients who were diagnosed by gastrofiberscopy at DONG SAN MEDICAL CENTER during past 5 years from 1982 to 1986. We analyzed them is terms of incidence of peptic ulcer, the ratio of grastric ulcer to duodenal ulcer, age and sex distribution, and the sites of gastric ulcer. We have got the following results. 1) We observed 1528 cases of peptic ulcer of which duodenal ulcer comprised 802 cases(52.5%) and gastric ulcer 726 cases(47.5%). 2) Annual incidence of peptic ulcer disease was variable. 3) As to the gastric ulcer, 642 cases(88.4%) were developed above 35 by age, but only 84 cases(11.6%) were developed below 35. 4) About the sites of gastric ulcer, antrum was more commonly involved than body below 60 by age. but in cases of above 60, body was more commonly involved(p<0.05). 5) The sex ratio )male: female)of gastric ulcer was 3.4:1 but in female, gastric ulcer occurred in older age group than in male(p<0.01). 6) In pediatric field, the incidence of duodenal ulcer was 3.4 times greater than that of gastric ulcer.

      • KCI등재후보

        미만성 조직구성 림프종의 임상적고찰

        남상숭,천종욱,조진환,김종서,강영우,송홍석 啓明大學校 醫科大學 1987 계명의대학술지 Vol.6 No.1

        A retrospective review is presented for 70 previously untreated adult patients with diffuse histiocytic lymphoma between March 1980 through March 1986 at the Keimyung University. The mean age was 51.4 years with a male to female ratio of 1.7:1. On admission, neck mass was the most frequent symptom in 31 cases(44%) and abdominal pain, fever, weight loss, dysphagia, anorexia, sore throat and abdominal distension were commonly presented. Physical findings revealed peripheral lymph node enlargement in 47 cases (67%) with cervical, inguinal, axillary in order of frequency. Abdominal mass was observed in 12 cases, hepatomegaly 12 cases and intussusception 2 cases and SVC syndrome, exophthalmos, scrotal mass in 1 case respetively. Extra-nodal involvement was 49 cases (70%) and GIT was most frequent site of involvement (15 cases). Laboratory findings revealed anemia in 33%, leukocytosis in 30%, leukopenia in 16%, thrombocytopenia in 7%, hypoproteinemia in 17%, increased alkaline phosphatase in 9% and increased SGOT in 20%. Local-regional involvement (stage Ⅰ-Ⅱ) occurred in 49% and advanced stage (stage Ⅲ-Ⅳ) in 51% and constitutional symptoms were associated with stage Ⅰ-Ⅱ in 15% stage Ⅲ-Ⅳ in 44%. Treatment was performed with radiotherapy in 12 cases, combination chemotherapy in 23 cases and combined modality therapy in 3 cases. Three year survival rate of complete responder is 92% and 3 year survival rate of local-regional disease was 82% and advanced disease was 33%.

      • KCI등재후보

        침윤성흉선종치료후 발생한 진정적혈구형성부전증 1 예

        송홍석,김용송,권석룡,천종욱,여인석 대한내과학회 1988 대한내과학회지 Vol.34 No.5

        Herein we wish to report a case of PRCA occurred after treatment with partial removal of an invasive thymoma and irradiation, followed by pancytopenia. Seven years ago, this male patient was accidentally found mediastinal mass on public health screening athis age of 37. Four years later, he received open thoracotomy and was found invasive thymoma which infiltrated pericarardium and pleura, and compressing superior vena cava and aorta. There after, he received 5, 000 rads of radiation. Since one month before admission, he complained of aggravated general weakness and dyspnea on exertion, Bone marrow smear revealed complete absence of erythroid and normal granulocytic and megakaryocytic series. With treatment of prednisolone and cyclophosphamide for 2 months, no significant response was obtained. After 5 months, peripheral blood disclosed pancytopenia; hematocrit of 5.5 gm/dl, WBC of 4,100/㎣, and platelet of 40,000/㎣.

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