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      • KCI등재후보

        약년자 위암에 관한 연구 - 약년자 , 위암 , 임상상 -

        박해옥(Hae Ok Park),최성규(Sung Kyu Choi),양대현(Dae Hyun Yang),조정곤(Jong Keun Cho),이숭(Soong Lee),윤경환(Kyung Hwan Yoon),유종선(Jong Sun Rew),윤종만(Chong Mann Yoon) 대한내과학회 1989 대한내과학회지 Vol.36 No.2

        N/A Carcinoma of the stomach, which remains the leading cause of death, could be treated successfully with early detection and curative resection, Carcinoma of the stomach in young adults is known to be so uncommon that it is often overlooked as is the case with a benign lesion, because the subjective symptoms are vague and nonspecific. In this regard, we intended to determine the clinicopathologic characteristics of this neoplasm in young adults and to find diagnostic clues for early detection. The hospital records of 39 patients, age 35 years or younger, seen at our institution between 1976 and 1986, were reviewed. The results were as follow: 1) Of the 863 cases of gastric carcinoma encountered 39 were 35 years of age or younger an incidence of 4.2% and the male to female ratio was 1.1:1.0 2) The mean time interval between the onset of symptoms and the first visit to a physician was 7.2 months, and the cases with complications or metastases at the time of diagnosis reached 50% and 56.4%, respectively. 3) Most of the symptoms were nonspecific and epigastric pain was the major symptom (59%). 4) The majority of tumors occurred in the lesser curvature side of the gastric body (51%), and were proximal to the gastric angle (64%). 5) The macroscopic findings in the 35 cases of advanced gastric cancer were in the order of frequency of type IV (33,4%), type IIL (28.2%), type II (17.9%), and type I (10.3%). 6) Histopathologic findings revealed that 90% (35 cases) of the cases were adenocarcinoma and 77% (27 cases) showed low grade differentiation. 7) Of the 15 cases which underwent surgical therapy, a resectable operation wss done in 11 cases, including 4 cases of early gastric cancer. These results may be helpful to diagnose and treat gastric cancer in young persons. In addition, it is suggested that a more aggressive and thorough diagnostic approach should be taken in young persons, which will help detect gastric cancer in the early stages.

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