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Consideration of the benefits of using a high current accelerator in BNCT
조일성,민선홍,박차원,김민호,이교철,이용진,홍봉환,임상무 대한방사성의약품학회 2020 Journal of radiopharmaceuticals and molecular prob Vol.6 No.1
Boron Neutron Capture Therapy (BNCT) has the advantage of selectively removing cancer cells ingesting boron compounds. In this study, the benefits for treatment time and boron compound injection dose were compared between current neutron sources and a high current neutron sources to be developed in near future. The time-activity curve (TAC) of GBM (Glioblastoma) for one bolus injection was obtained by applying modified 3 compartment model. The treatment time was determined for an accelerator-based neutron sources at the present time and a high current accelerator based neutron source to be developed in the near future. In the case of the double amount of IAEA-recommended neutron flux, the treatment time was shortened to 15 minutes. In the case of high current accelerators, which are five times the amount of IAEA-recommended neutron flux, the irradiation time is within 5 minutes. The use of a high current accelerator based neutron source in BNCT is advantageous in terms of treatment time. In addition, it can increase the efficiency of use of neutrons and reduce the boron compound injection dose to patients, thus reducing pharmacological toxicity.
Analysis of the Thermal Dome Effect from Global Solar Radiation Observed with a Modified Pyranometer
조일성,이규태,지준범,김부요 한국광학회 2017 Current Optics and Photonics Vol.1 No.4
Solar radiation data measured by pyranometers is of fundamental use in various fields. In the field ofatmospheric optics, the measurement of solar energy must be precise, and the equipment needs to bemaintained frequently. However, there seem to be many errors with the existing type of pyranometer, whichis an element of the solar-energy observation apparatus. In particular, the error caused by the thermal domeeffect occurs because of the thermal offset generated from a temperature difference between outer domeand inner casing. To resolve the thermal dome effect, intensive observation was conducted using the methodand instrument designed by Ji and Tsay. The characteristics of the observed global solar radiation wereanalyzed by classifying the observation period into clear, cloudy, and rainy cases. For the clear-weathercase, the temperature difference between the pyranometer’s case and dome was highest, and the thermaldome effect was 0.88 MJ m-2 day-1. Meanwhile, the thermal dome effect in the cloudy case was 0.69MJ m-2 day-1, because the reduced global solar radiation thus reduced the temperature difference betweencase and dome. In addition, the rainy case had the smallest temperature difference of 0.21 MJ m-2 day-1. The quantification of this thermal dome effect with respect to the daily accumulated global solar radiationgives calculated errors in the cloudy, rainy, and clear cases of 6.53%, 6.38%, and 5.41% respectively.