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RISS 인기검색어
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- 저자 : 정홍명 ( Hong Myung Jung ) (검색결과 2 건)
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증례 : 소화기 ; 전신홍반루푸스에 동반된 자가면역 간염 1예
황영준 ( Young Jun Hwang ),정홍명 ( Hong Myung Jung ),박혁 ( Hyeuk Park ),문장식 ( Jang Sik Mun ),명보현 ( Bo Hyun Myung ),김도현 ( Do Hyun Kim ),김호동 ( Ho Dong Kim ) 대한내과학회 2010 대한내과학회지 Vol.78 No.1
전신홍반루푸스 환자에서 간효소 수치의 상승이 보였을 때 예후와 치료를 위해 원인을 파악하는 것은 중요하다. 특히 루푸스 간염과 자가 면역 간염을 감별하는 것은 필요하지만 두 질병의 유사성 때문에 감별이 쉽지 않다. 현재 문맥 주위의 조각 괴사, 간세포의 rossetting, 두터운 림프구 침윤과 같은 조직학적 소견과 antiribosomal P protein 항체, anti ds DNA 항체, anti Sm 항체 등의 자가항체가 두 질병을 구별하는데 도움을 줄 수 있다고 알려져 있으나 명확한 구별법은 아직 확립되지 않은 상태이다. 따라서 향후 이에 대한 연구가 필요하다고 사료되며 본 저자는 자가 면역성 간염과 동반된 전신홍반루푸스를 진단하고 스테로이드 치료로 호전된 증례를 경험하였기에 보고하는 바이다. Autoimmune hepatitis accompanied by systemic erythematosus lupus is rare. Usually, lupus-related advanced liver involvement is indistinguishable from autoimmune hepatitis accompanied by lupus, as they share common clinical, biochemical, serological, and histological manifestations. However, each disease has its own diagnostic criteria, and they have been defined as two different categories. Therefore, distinguishing between the two diseases is important to determine the correct diagnosis and treatment. A 41-year-old woman was hospitalized with jaundice and a malar rash. The patient met the diagnostic criteria of both systemic erythematosus lupus and autoimmune hepatitis. After corticosteroid treatment, the patient`s condition improved. Therefore, we report our experience of a rare case of autoimmune hepatitis accompanied by systemic erythematosus lupus with a review of the literature. (Korean J Med 78:95-98, 2010)
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큰 관상동맥 병변에서 약물방출스텐트와 금속스텐트의 임상경과 비교
김우종 ( Woo Jong Kim ),조장현 ( Jang Hyun Cho ),정종혁 ( Jong Heok Jung ),이민근 ( Min Kun Lee ),윤재성 ( Jae Sung Yoon ),안용수 ( Young Soo Ahn ),황영준 ( Young Jun Hwang ),정홍명 ( Hong Myung Jung ),김수현 ( Su Hyun Kim ),김준 대한내과학회 2011 대한내과학회지 Vol.80 No.6
Background/Aims: Drug-eluting stents (DES) are superior to bare metal stents (BMS) in reducing restenosis rates across a wide range of patients and lesion subsets.This study compared the clinical outcomes of DES versus BMS in patients with large coronary Methods: The study compared 134 patients (59.9±10.6 years, 90 men, 44 women) who underwent single vessel angioplasty with DESimplantation in large vessels with 115 patients (60.3±8.9 years, 82 men, 33 women) who received BMS. The clinical outcomes at 12 months were compared between groups. The study end points were major adverse cardiac events (MACE), including cardiac death, nonfatal myocardial infarction, and the need for target vessel and target lesion revascularization. Results: The baseline clinical coronary angiography and procedural characteristics were similar in both groups. The duration of dual antiplatelet therapy was longer in the DES group than in the BMS group (240±2.7 vs. 348±1.7 days, p=0.042). During the 12-month clinical follow-up, MACE were observed in 13 patients (11.3%) with BMS and 12 patients (9.0%) with DES (p=0.486). Conclusions: For coronary stents implanted in large coronary arteries, DES seems to be more favorable, although no significant differences were observed in the clinical outcomes between DES and BMS during a 1-year clinical follow-up. (Korean J Med2011;80:664-671)
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