팥 앙금 제조 과정에서 발생하는 1차, 2차 및 3차 자숙액의 항산화성 및 생리활성 비교

이연지(Yeon-Ji Lee),김원석(Won-Suk Kim),전유진(You-Jin Jeon),김용태(Yong-Tae Kim) 한국식품영양과학회 2021 한국식품영양과학회지 Vol.50 No.11

본 연구에서는 팥 앙금을 제조하는 과정에서 발생하는 부산물인 1차, 2차 및 3차 자숙액(가공 처리수)의 총 폴리페놀 및 플라보노이드 함량, 항산화 활성 및 생리활성을 측정하여 팥 자숙액을 이용한 건강 기능성식품 및 의약품 소재로서의 활용 가능성을 탐색하고자 하였다. 팥 자숙액의 총 폴리페놀 및 플라보노이드 함량을 측정한 결과, 1차 자숙액의 총 폴리페놀(92.30 ㎎/g) 및 플라보노이드(11.54 ㎎/g) 함량이 2차 및 3차 자숙액에 대비하여 2~5배 높은 경향을 나타내었다. 또한 팥의 1차 자숙액의 ABTS 라디칼 소거 활성의 IC50은 0.18 ㎎/mL, DPPH 라디칼 소거 활성의 IC50은 1.24 ㎎/mL, 아질산염 소거 활성의 IC50은 1.82 ㎎/mL, 환원력의 EC50은 0.08 ㎎/mL로 나타나 3가지 자숙액 중에서 가장 높은 항산화 활성을 내포하고 있는 것으로 확인되었다. 팥자숙액의 생리활성을 확인하기 위하여 피부 미백, 주름 개선, 및 항당뇨 관련 효소의 활성을 측정한 결과, 1차 자숙액에서 tyrosinase(IC50, 0.40 ㎎/mL), elastase(IC50, 0.84 ㎎/mL) 및 α-glucosidase(IC50, 4.28 ㎎/mL)의 저해 활성이 확인되었다. 또한 팥 자숙액의 치매 관련 효소인 AChE 및 BACE1의 활성을 측정한 결과, 1차 자숙액에서 각각 35.81% 및 54.90% 효소 활성이 저해되는 것으로 확인되었다. 본 연구결과로부터 팥 앙금 제조 과정에서 폐기되는 1차 자숙액에는 폴리페놀 및 플라보노이드 함량이 높고 우수한 항산화 활성 및 생리활성을 내포하는 생리 기능성 물질이 함유되어 있는 것으로 확인되었다. 따라서 팥 1차 자숙액은 기능성식품 및 화장품을 비롯한 식품첨가제 등의 천연 소재로서 활용 가능하리라 판단된다. This study evaluated the antioxidant and physiological activities of processed water (PW) generated during the preparation of red bean paste. The three types of PW were prepared by heat treatment for 35 min at 95℃ (1st PW), 35 min at 95℃ (2nd PW), and 20 min at 100℃ (3rd PW), sequentially. The total polyphenol and flavonoid contents of the 1st PW were 92.30 mg/g and 11.54 mg/g, respectively. The polyphenol and flavonoid content of the PW decreased as the number of heat treatments increased. The 1st PW showed the highest 2,2′-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) and 2,2-diphenyl-1-picrylhydrazyl radical scavenging activity, nitrite scavenging activity, and reducing power. The antioxidant activities of PW also significantly decreased as the number of heat treatments increased. Whitening, anti-skin-aging, and anti-diabetic activities were observed in the 1st PW. Furthermore, the highest inhibitory activities of acetylcholinesterase and β-secretase were also observed in the 1st PW. These results indicate that the 1st PW of red bean paste may be useful as an antioxidant and functional substance in food and pharmaceutical products.

CSR 활동에 따른 재무성과 연구: 기업의 투자요인 중심으로

이연지 ( Yeon-ji Lee ),신정순 ( Jung-soon Shin ) 한국재무관리학회 2021 財務管理硏究 Vol.38 No.3

본 연구는 2015년부터 2019년까지 한국 유가증권시장에 상장된 기업 중 ESG통합등급과 KEJI 지수를 부여받은 기업들을 대상으로 기업의 투자요인들과 CSR 활동에 따른 재무성과의 관계를 알아보고자 다음과 같은 분석을 시도하였다. 첫째, 기업의 투자요인들 각 요소들과 CSR 성과가 기업의 재무성과에 영향을 미치는지 실증 분석하였다. 둘째, 기업의 투자요인과, CSR 성과와 기업의 재무성과 간의 영향을 살펴보았다. 본 연구의 실증 분석 결과는 다음과 같다. 첫째, CSR 성과지표를 ESG통합등급으로 사용한 결과로, CSR과 기술개발, 광고 선전, 기업 규모, 부채비율, 영업위험, 업력과는 기업 가치에 영향을 주는 것으로 나타났고, KEJI 지수 또 한 부채비율 및 영업현금흐름을 제외하고는 기업 가치를 향상시키는 것으로 나타났다. 둘째, 기업의 투자요인들을 포함시켜, ESG통합등급으로 CSR을 분석한 경우, 투자요인 중 기술개발과 광고 선전만이 기업 가치를 높이는데 일조한다는 사실을 발견했다. KEJI 지수의 경우, 투자 요인들 모두 기업 가치를 높이며, 조절효과가 있음을 알 수 있었다. 이러한 결과들은 ESG통합등급과 KEJI 지수가 CSR지수로 크게 다르지 않은 결과를 도출하며, 기업 가치를 높이는데 기업의 투자요인들과 CSR은 일조함을 보여준다. This study attempted the following analysis to explore the relationship between the company’s investment factors and its financial performance based on CSR activities among companies listed on the Korea Stock Market from 2015 to 2019 that were given ESG Integration Rating and KEJI Index. First, we empirically analyze whether each component of an entity’s investment factors and CSR performance affect the entity’s financial performance. Second, we looked at the investment factors of the company and the impact between CSR performance and the financial performance of the company. The results of the empirical analysis of this study are as follows. First, the results of using CSR performance indicators as ESG integrated classes showed that CSR and technology development, advertising propaganda, corporate size, debt ratio, operating risk, and performance affected corporate value, and KEJI index also improved corporate value except for debt ratio and operating cash flows. Second, in the case of analyzing CSRs with ESG integrated ratings, we found that only technology development and advertising propaganda among the investment factors contribute to enhancing corporate value. In the case of the KEJI index, it was shown that all investment factors increase corporate value and have a controlling effect. These results show that ESG’s integrated rating and KEJI index are not much different from the CSR index, and that corporate investment factors and CSR contribute to enhancing corporate value.

어린이 전문병원의 색채 환경과 아동심리에 관한 특성분석

이연지(Lee, Yeon Ji),김경숙(Kim, Kyung Sook) 한국디지털디자인협의회 2014 (사)한국디지털디자인협의회 conference Vol.2014 No.5

The hospital for children, color environment of excess primary colors it does not take into account the environment of healing and stress children feel is applied. Therefore, in the limited space in the atmosphere is the place of the main public hospital, we investigated the hospital four places of children typical of Seoul. Visit the site under investigation, we are made in the image of the photo taken, by using the NCS color system, we classify the current state of the color. As a result, we analyzed the effects and psychological effects of color plan of the hospital has on the children. Hospital of four locations were used Y of brightness and high saturation, YR, B, the GY. This color possible to know that it does not take into account the psychological effects of colors in a hospital setting, Y increases stress and induce lazy YR and boring given to children. Therefore, follow-up studies to provide a color scheme which is suitable for hospital in colors children like are required.

플래그쉽 스토어의 아이덴티티 형성 요인에 관한 연구 -SPA브랜드중심으로-

이연지 ( Yeon Ji Lee ),사영재 ( Young Jae Sa ),김경숙 ( Kying Sook Kim ) 한국기초조형학회 2015 기초조형학연구 Vol.16 No.1

소비자에게 브랜드를 효과적으로 전달하기 위하여, 기업들은 브랜드 이미지를 통한 아이덴티티 형성하는 주요한 요인인 ‘플래그쉽 스토어(Flagship Store)``를 제공하고 있다. 본 연구는 공간마케팅의 핵심인 플래그쉽 스토어 중 SPA브랜드를 중심으로 소비자에게 각인되는 플래그쉽 스토어 이미지의 아이덴티티 형성 요인을 분석하여, 향후 상업공간의 브랜드 마케팅에서 플래그쉽 스토어를 통한 공간 디자인의 방향을 모색하는데 있다. 방법은 소비자 리서치를 통해 조사·분석하기로 하며, 플래그쉽 스토어의 개념과 브랜드 아이덴티티 형성 및 소비자 인지요인에 관한 이론고찰을 시행, 사례를 쇼카드로 제시 후 타겟층인 10대-30대의 소비자를 대상으로 설문을 실시하고, 브랜드 회상과 재인의 비교분석을 통해 소비자 인지요인을 분석하였다. 결과는 플래그쉽 스토어가 소비자와 기업이 접점을 이루는 공간 마케팅으로 기억-연상 작용을 일으키는 이미지마케팅은 소비자에게 긍정적으로 인지하게 되어 브랜드의 이윤과 매출성장에 많은 영향을 준다. 또한 실내디자인의 브랜드 아이덴티티 요인은 분위기, 색상, 조명으로 공간적 요소를 통해 얼마만큼 편안함과 쾌적함을 제공하는가에 있음을 알 수 있다. 이에 따라 소비자들이 감성으로 공간을 인지하고 있음을 확인할 수 있다. 플래그쉽 스토어가 브랜드 제품에 대한 정체성을 가지고 정확한 타겟층의 니즈를 파악하여 공간요소, 조명, 색상 오브제, 가구 및 세부적인 요소들에 브랜드만의 독특한 문화적인 가치를 담아야 한다는 것이다. In order to provide a brand effectively to consumers, Companies have to provide is a major factor in identity formation using the brand image ``flagship store (Flagship Store)``. In this study, in the heart of the SPA brand of important flagship store marketing of space, by analyzing the factors of identity formation of the flagship store images that are imprinted on the consumer, the brand marketing of commercial space in the future at it is to seek the direction of the design space through the flagship store. Was decided to research and analysis through the consumer research, to perform theoretical Study of factors is the consumer with the formation of brand identity and concept of the flagship store, presented to show the card case, the method, the target layer the questionnaire was conducted targeting consumers teenage generation is -30, and analyzed factors of whether a consumer through a comparative analysis of Jane brand recollection. The flagship store, research results, remember the marketing of the space in which consumers and businesses makes contact - image marketing that causes an associative effect sales and profit of the brand so as to recognize positively to consumer I give a great influence on the growth of. Factors brand identity interior design of Flagship store, can know that it is to provide comfort and comfort degree through the spatial element atmosphere, color and lighting. This makes it possible to confirm that the consumer is aware of the spatial sensibility. To understand the needs of the exact target audience that has the identity of the brand product flagship store, unless put the cultural value of the brand unique spatial elements, lighting, objects of color, the elements and detailed furniture I hear that not.

모래지치(Messerschmidia sibirica) 추출물의 항산화성 및 생리활성

이연지 ( Yeon-ji Lee ),김지윤 ( Ji-youn Kim ),김원석 ( Won-suk Kim ),김용태 ( Yong-tae Kim ) 한국수산과학회 2021 한국수산과학회지 Vol.54 No.6

Messerschmidia sibirica is a halophyte that grows in high-salinity areas of coastal sand dunes and sandy shores. This study was conducted to investigate the constituents, antioxidant potency, and physiological activities of M. sibirica. Mineral analyses revealed that potassium, calcium, sodium, and magnesium were the most prevalent minerals in M. sibirica leaves and stems. We used 70% ethanol, 80% methanol, and distilled water as solvents to prepare extracts from M. sibirica tissues, with extraction yields of between approximately 19% and 27% being obtained. Among the six types of extract, the leaf ethanol extract (LEE) was characterized by the highest total polyphenol and flavonoid contents, and the antioxidant activities of the LEE were also the highest among the different solvent extracts. In addition, the leaf water extract was shown to have the highest tyrosinase and α-glucosidase inhibitory activities, whereas the leaf methanol extract was found to have the highest elastase inhibitory activity. Notably, all leaf extracts were established to have more than 75% β-secretase (BACE1) inhibitory activity at a final concentration of 0.5 mg/mL. These results indicate that leaf extracts of M. sibirica may have beneficial antioxidant properties, and could thus have potential application as functional supplements in food and pharmaceutical products.

백혈병 진단을 위한 CNN 모델 비교 분석

이연지(Yeon-Ji Lee),류정화(Jung-Hwa Ryu),이일구(Il-Gu Lee) 한국정보통신학회 2022 한국정보통신학회 종합학술대회 논문집 Vol.26 No.1

급성 림프모구성 백혈병은 골수 내 미성숙 림프구 과다증식으로 인해 골수 기능이 억제되어 발생하는 급성 백혈병이다. 성인 급성 백혈병의 30% 비율을 차지하고 있으며, 소아는 항암화학요법으로 80% 이상의 완치율을 보이는 반면, 성인은 20%~50%로 저조한 생존율을 보이고 있다. 그러나 급성 림프모구성 백혈병 진단을 위한 의료영상 데이터 기반 머신러닝 알고리즘에 관한 연구가 초동 단계이다. 본 논문에서는 신속하고 정확한 진단을 위해 CNN 알고리즘모델들을 비교분석한다. 네 가지 모델을 사용하여 급성 림프모구성 백혈병 진단 모델들을 비교분석하기 위한 실험 환경을 구축하고 주어진 의료영상 데이터에 대해 정확도가 가장 우수한 알고리즘을 선택하였다. 실험 결과에 따르면 네 가지의 CNN 모델들 중에서 InceptionV3모델이 98.9%의 정확도로 가장 우수한 성능을 보였다. Acute lymphoblastic leukemia is an acute leukemia caused by suppression of bone marrow function due to overgrowth of immature lymphocytes in the bone marrow. It accounts for 30% of acute leukemia in adults, and children show a cure rate of over 80% with chemotherapy, while adults show a low survival rate of 20% to 50%. However, research on a machine learning algorithm based on medical image data for the diagnosis of acute lymphoblastic leukemia is in the initial stage. In this paper, we compare and analyze CNN algorithm models for quick and accurate diagnosis. Using four models, an experimental environment for comparative analysis of acute lymphoblastic leukemia diagnostic models was established, and the algorithm with the best accuracy was selected for the given medical image data. According to the experimental results, among the four CNN models, the InceptionV3 model showed the best performance with an accuracy of 98.9%.

추출용매에 따른 톳(Hizikia fusiformis) 추출물의 항산화 및 생리활성 비교

이연지 ( Yeon-ji Lee ),전유진 ( You-jin Jeon ),김용태 ( Yong-tae Kim ) 한국수산과학회(구 한국수산학회) 2020 한국수산과학회지 Vol.53 No.6

The seaweed Hizikia fusiformis is rich in protein, carbohydrates, vitamins, and minerals. This study investigated the antioxidant and physiological activities of H. fusiformis extracts prepared with 70% ethanol, 80% methanol, or distilled water. The extraction yields of these various solvent extracts were as follows: ethanol extract, 15.26%; methanol extract, 17.95%; and water extract, 45.62%. The methanol extract showed the highest total polyphenol content (24.06 mg GAE/g), but total flavonoid content was similar in all extracts. ABTS (2,2'-Azino-bis(3-ethylbenzothiazoline-6-sulfonic acid)) radical scavenging activity was highest in the ethanol extract (IC₅₀: 0.90 mg/mL), while the methanol extract exhibited the strongest DPPH (2,2-diphenyl-1-picrylhydrazyl) radical scavenging activity (IC₅₀: 8.09 mg/mL), reducing power (EC50: 0.40 mg/mL), and ferric reducing antioxidant power (0.28 mM). By contrast, tyrosinase and α-glucosidase inhibitory activities were higher in the ethanol extract than in the other extracts. The high BACE1 (β-secretase) inhibitory activity was observed in the ethanol extract (IC₅₀: 1.03 mg/mL). These results indicate that H. fusiformis ethanol extracts may be useful for their antioxidant and functional properties in food and pharmaceutical materials.

톳(Hizikia fusiformis)을 첨가한 흰찰쌀보리죽의 제조 및 품질특성

이연지 ( Yeon Ji Lee ),임승용 ( Seung Yong Lim ),김원석 ( Won Suk Kim ),김용태 ( Yong Tae Kim ) 한국수산과학회(구 한국수산학회) 2016 한국수산과학회지 Vol.49 No.3

This study was conducted to evaluate the physicochemical characteristics, perform a sensory evaluation of glutinous barley gruel after adding Hizikia fusiformis powder to promote consumption, and identify the best ratio and recipe. The gruel was prepared with rice and glutinous barley powder, and various levels (0, 2.5, 5.0, and 7.5%) of H. fusiformis powder. pH, color, viscosity, and spreadability of the gruel were investigated. A sensory evaluation was conducted by 20 panelists in the categories of color, flavor, taste, texture appearance, and overall preference using a 9□point hedonic scale. The viscosity and pH of the gruel increased as H. fusiformis powder content increased, whereas spreadability of the gruel decreased gradually as H. fusiformis powder content increased. As the level of H. fusiformis powder increased, lightness decreased significantly, whereas redness and yellowness increased. Color, bitter taste, and H. fusiformis flavor of the gruel increased significantly as H. fusiformis powder content increased. On the other hand, sweet taste (delicious taste level) and viscosity were not different among the different gruels. The sensory test results indicated that the gruel with 5% H. fusiformis powder had the best overall acceptability. In conclusion, glutinous barley gruel with 5% added H. fusiformis powder was more acceptable than the others.

온도에 의해 유도된 2단계 배양전략을 통한 미세조류 Chlorella vulgaris와 Dunaliella salina의 지질과 탄수화물의 축적량 변화

이연지 ( Yeon-ji Lee ),이치헌 ( Chi-heon Lee ),조기철 ( Kichul Cho ),문혜나 ( Hye-na Moon ),남궁진 ( Jin Namgung ),김기혁 ( Ki-hyuk Kim ),임병진 ( Byung-jin Lim ),김대경 ( Daekyung Kim ),여인규 ( In-kyu Yeo ) 한국수산과학회(구 한국수산학회) 2017 한국수산과학회지 Vol.50 No.1

The aim of this study was to evaluate a temperature-induced two-stage cultivation (TTC) strategy for the regulation of lipid and carbohydrate production by two microalgae, Chlorella vulgaris and Dunaliella salina, for biofuel production. The microalgae were grown under several temperature conditions (15, 25, 35, and 45°C) and optimal growth was observed at 25°C for both microalgae. To test the TTC, aseptically cultured microalgae were incubated under optimal conditions (25°C) for 20 days, and then divided into four aliquots that were incubated at 15, 25, 35, and 45°C for 5 days. Similar but somewhat decreased growth rates were observed at the non-optimal temperatures (15, 35, and 45°C). In addition, while total lipid accumulation increased in a temperature-dependent manner in both microalgae, total carbohydrate increased with temperature in C. vulgaris but decreased in D. salina. However, for lipid and carbohydrate production, while the highest lipid productions of C. vulgaris and D. salina were observed at 25°C and 35°C, respectively, the highest total carbohydrate productions of C. vulgaris and D. salina were obtained at 15°C and 25°C, respectively. These results suggest that the TTC strategy may be easily and efficiently applied to bioprocessing for biofuel production.

넓패(Ishige foliacea) 추출물의 피부노화 억제활성

김지윤 ( Ji-youn Kim ),박다빈 ( Da-bin Park ),이연지 ( Yeon-ji Lee ),박선주 ( Sun Joo Park ),김용태 ( Yong-tae Kim ) 한국수산과학회 2023 한국수산과학회지 Vol.56 No.6

In this study, the antioxidant and anti-skin aging properties of the Korean marine algae Ishige foliacea were investigated. Solvent extracts from I. foliacea were prepared with 70% ethanol, 80% methanol, and water. The extraction yields of various solvent extracts ranged from 9.55% to 35.12%. In terms of antioxidant activity, the ethanol extract showed the highest ABTS (2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) diammonium salt) radical scavenging activity, nitrite oxide scavenging activity, reducing power, and FRAP (ferric reducing antioxidant power). Regarding anti-skin aging activity, evaluation of the skin whitening and anti-wrinkle activities revealed that the methanol, water, and ethanol extracts possessed the highest tyrosinase (IC₅₀=0.98 mg/mL), elastase (IC₅₀=0.15 mg/ mL), and collagenase (IC₅₀=0.06 mg/mL) inhibitory activities, respectively. These results suggest that I. foliacea holds potential as an antioxidant and anti-skin aging substance in food and cosmetic materials.