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행소음전탕액(杏蘇飮煎湯液)이 가토혈장(家兎血漿) COTISOL농도(濃度) 및 $PCO_2,\;CO_2$와 GUINEA PIG의 기관지(氣管支) 평활근(平滑筋)에 미치는 영향(影響)
이승호,Lee, Sueng-Ho 대한한방내과학회 1992 大韓韓方內科學會誌 Vol.13 No.1
The following results were obtained from the observation on the change of plasma cortisol concentration in the experiment of intravenous administration of Haengsoyeum Water Extract in the rabbit. And the effects of Haengsoyeum extract on the contractile force of the isolated guinea pig trachea smooth muscle. 1. In intravenous administration the plasma cortisol concentration increased significantly about 1 hours after with a does of 0.2 ml/kg. 2. In intravenous administration the plasma cortisol concentration increased significantly about from 1 to 3 hours after with a does of 0.4 ml/kg. 3. The contractile response of the trachea smooth muscle of isolated guinea pig to histamine $10^{-4}\;M$ was significantly inhibited by Haengsoyeum extract. 4. The contractile response of the trachea smooth muscle of isolated guinea pig to acetylcholine $10^{-4}\;M$ was considerably inhibited by Haengsoyeum extract. 5. The contractile response of the trachea smooth muscle of isolated guinea pig to 5-hydroxytryptamine $10^{-4}\;M$ was inhibited by Haengsoyeum extract.
The Structure of Kushenol M from Sophora flavescens
Ryu, Shi Yong,Lee, Seung Ho,No, Zaesung,Kim, Kye-Young,Lee, Sueng-Geun,Ahn, Jong Woong 영남대학교 약품개발연구소 1995 영남대학교 약품개발연구소 연구업적집 Vol.5 No.-
The linkage pattern of two side chains i.e., a isopentenyl and a lavandulyl group in kushenol M(I), a flavonoid form Sophora flavescns was established by the aid of 2-D NMR techniques, especially DEPT, ¹³C-¹H COSY and COLOC experiments. Thus, I was unequivocally determined and (2R, 3R)-5, 7, 2', 4'-tetrahydroxy-6-isopentenyl-8-lavandulylflavanonol.