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이수길,김도영,김충혁,이준웅 한국전기전자재료학회 1992 電氣電子材料學會誌 Vol.5 No.1
유한요소법은 거의 모든 물리계를 대상으로 특정범위의 해석을 할수있는 방법이며 이에 경계요소법등을 보강하면 각종 센서류등으로만 측정이 가능한 여러가지 고체역학적측정, 유체역학적측정, 전자계적측정 및 물성적측정등을 몇가지의 관련 데이타를 가지고 수행할 수 있는 Tool을 만드는데 주도적 역할을 할 것으로 사료된다. 그리고 실제로 유한요소법을 기초로한 유용한 Simulator들이 실용화되어 있는 실정이며 특히 물성계를 해석하는 Simulator의 개발이 미개척분야로 남아있어 첨단 신소재 개발분야에 대한 연구가 요구된다.
A Study on Environmental Monitoring of Fluorouracil andDecontamination Reagents
이수길,이내우 한국안전학회 2009 한국안전학회지 Vol.24 No.4
This study has been to examine the occupational exposure levels of Fluorouracil (5-FU) in a hospital and to investigate the most effective cleaning reagent for control. Fluorouracil is one of the cytotoxic drugs which are therapeutic agents used to treat cancer. The health practitioners working in the cytotoxic work room and oncology ward areas are exposed to adverse health risks like cytogenetic and DNA damage from cytotoxic drugs exposure by frequent skin contact from contaminated surfaces. Four kinds of cleaning reagents has been examined to degrade the 5-FU. It was found that 5-FU was only degraded soon after the reaction in 0.5%(w/v) NaClO solution. Therefore, 0.5%(w/v) NaClO solution has been chosen to decompose any residues on the contamination surfaces. A substantial level of contamination was found on the surfaces of cytotoxic work room and oncology ward areas. The contamination ranges of the surfaces in cytotoxic work room and oncology ward areas were from 2.0 to 13.8µg/㎡ and 5.39 to 11.53µg/㎡, respectively. Consequently, regulation of the occupational exposure limit, procedure of special cleaning, and the use of personal protective equipment are recommended during the manipulation and administration of the drugs to avoid skin contamination from cytotoxic drugs like 5-FU.