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이선희,김성훈,Lee, Seon-Hui,Kim, Seong-Hun Korean Chemical Society 2004 대한화학회지 Vol.48 No.5
We designed and synthesized compounds which have negative dielectric anisotropy (N type) for VA-LCD mode. Due to the large dipole moments toward the minor axis of molecule and anisotropy of polarizability, they can be used as N type LC. F atom and NCS group and propyl group were introduced as substituents on bicyclohexylbenzene core unit and alkyl chains (propyl~heptyl) were introduced on terminal part. All of the synthesized compounds showed negative dielectric anisotropy as expected. 수식배향(VA) 모드 액정디스플레이에 사용될 수 있는 음의 유전율 상수를 갖고 있는 화합물들을 고안합성하였다. 이들은 분자의 단축방향으로 큰 쌍극자 모멘트와 큰 분극성을 갖고 있어 N 형태의 액정으로 사용될 수 있다. 중심의 바이싸이클로헥신벤젠에 플로오린과 NCS기를 말단부분에 알킬기를 도입하였다. 합성된 화합물등은 예상대로 음의 유전율 이방성을 보여 주었다
체외 순환후 지혈에 대한 저농도의 Aprotinin 효과
이선희,최승호,곽문섭,Lee, Seon-Hui,Choe, Seung-Ho,Gwak, Mun-Seop 대한흉부심장혈관외과학회 1996 Journal of Chest Surgery (J Chest Surg) Vol.29 No.2
The effect of low-dose aprotinin on hemostasis in patients undergoing cardiopulmonary bypass (CPB) for repeat valve replacement and coronary artery bypass operations were investigated. Thirty patients undergoing elective CPB from February 1993 through February 1995 at Catholic Medical Center were studied. the patients were randomly divided into two groups(15 patients per group) : group 1, receive 1, 000, 000 KIU/kg aprotinin in the CPB priming volume and 20, 000 KIU/kg aprotinin intravenously each hour during CPB ; group 2, without aprotinin administration served as the controls. The result showed that the early postoperative (during the first 24 hours) and mean postoperative total blood loss of the aprotinin group were significantly reduced than the control group (317.2 $\pm$ 89.6ml in the aprotinin group versus 821.3 $\pm$ 441.2rnl in the control group, p<0.01 ; 767.2 $\pm$ 214.1 ml in the aprotinin group versus 1562.5 $\pm$ 735.2 rnl in the control gorup, p<0.01). Total use of packed red ells and fresh frozen plasma was higher in control group(1.22 $\pm$ 0.3 units versus 4.21 $\pm$ 1.7units of packed red cells, p<0.01 : and 2.37 $\pm$ 0.4units versus 6.72 $\pm$ 0.88uni1s of fresh prozen plasma, p<0.05). We conclude the low-dose aprotinin was positive influence on postoperative blood loss in undergoing highly bleeding potency cardiac operation.
이선희,권종범,최승호,Lee, Seon-Hui,Gwon, Jong-Beom,Choe, Seung-Ho 대한흉부심장혈관외과학회 1996 Journal of Chest Surgery (J Chest Surg) Vol.29 No.2
From 1990 to 1994, 10 patients were treated for tracheobronchial injury due to blunt trauma. 7 injuries resulted from motor vehicle accident. Common presenting signs included subcutaneous emphysema, dyspnea and hemoptysis. The most common radiologic findings were pneumothorax, pneumomediastinum and hemothorax. The fiberoptic bronchoscopy was highly accurate method for the diagnosis. The operation method is simple closure except one patien underwent right pneumonectomy. One patient died because of respiratory distress and 9 patients recovered uneventfully and returned to normal activity. Early recognition and proper treatment of tracheobronchial injury is important. 1990년 1월부터 1994년 12월까지 4년간의 들상에 의한 외상성 기도손상으로 10명의 환자가 응급실로 내원하였다. 7명은 자동차 사고였고 3명은 산업재 해였다. 내원시 주증상은 피하기종, 호흡부전, 각혈 등이였다. 방사선학적 소견은 주로 기흥, 종격동기흥, 혈흥 등이 었다. 기관지내시경은 내원 초기에 매우 유효한 검사이다. 파열부위는 우폐 전적출술을 한 1명을 제외하고 단순봉합하였다. 술후 1명이 폐좌상으로 인한 급성호흡부전으로 사망하였으며 9명은 별다른 합병증없이 일상생활로 복귀하였다. 외상성 기도손상환자의 치료에 있어서 중요한 것은 조기진단과적절한 치료이다.