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소각로 인근에서 재배되는 농산물의 다이옥신류 모니터링 및 위해도 평가에 관한 연구
신희창 ( Hee-chang Shin ),홍경숙 ( Kyong-suk Hong ),안재민 ( Jae-min An ),윤혜정 ( Hye-jeong Yun ),김성연 ( Sung-youn Kim ),유경은 ( Kyung-eun Yu ),윤재돈 ( Jae-don Yun ),이재훤 ( Jae-hwon Lee ),김동호 ( Dong-ho Kim ) 한국환경농학회 2016 한국환경농학회 학술대회집 Vol.2016 No.-
Dioxins(PCDDs; Polychlorinated dibenzo-p-dioxins, PCDFs; Polychlorinated dibenzofurans) are accumulated in the body through the food as a representative environmental pollutants. Dioxins are flowed into the environment through the incineration of chemical products and electrical products containing PCBs. Dioxins generated from incinerators can pollute the atmosphere and soil, and it were accumulated in the body through food. Therefore, the dioxins monitoring of agricultural products produced near incinerators are required to ensure the safety of agricultural products. In this study, the analysis of dioxins was carried out on the basis of the law of the U.S Environment Protection Agency (EPA) Method 1613 and Korean Food Standards Codex Method SOP. The fifty agricultural products were collected in the field around the incinerators. As a result, the concentration range of detected dioxins was (0.0507~0.5824) pg/g. In the range of concentrations that reflect the toxic equivalent factor is (0.00002~0.01631) TEQ pg/g. The contribution of agricultural products to the dioxins intake is not equally distributed: tomato (74%), Corn (15%), Cabbage (9%), Green pepper (2%), red pepper (0.04%), Blueberries (0.0006%). The estimated daily intake of Korean Population through agricultural products was 0.00430 pg TEQ/kg body weight/day, and it was estimated at about 0.11% of tolerable daily intake(TDI) of Korea. Consequently, Dioxins exposure levels of agricultural products produced near incinerators has been found to be very safe.
안재민 ( Jae-min An ),홍경숙 ( Kyong-suk Hong ),윤혜정 ( Hye-jeong Yun ),김성연 ( Sung-youn Kim ),유경은 ( Kyung-eun Yu ),신희창 ( Hee-chang Shin ),윤재돈 ( Jae-don Yun ),이재훤 ( Jae-hwon Lee ),김동호 ( Dong-ho Kim ) 한국환경농학회 2016 한국환경농학회 학술대회집 Vol.2016 No.-
The present study was carried out to reduction of lead(Pb), cadmium(Cd), mercury(Hg), arsenic(As), chromium(Cr) and nickel(Ni) concentrations by 5 milling degrees(0.0%, 2.4%, 4.8%, 7.2% and 9.6%, from husked rice to polished rice) in rice. Recently, various rice by milling degree is sold for health and taste. To provide safe food to consumers, it is need to know the change of their concentrations according to milling degree of rice. Pb, Cd, As, Cr and Ni analysis in milled rice 255 samples were performed using microwave device and Inductively Coupled Plasma Mass Spectrometry(ICP/MS), whereas mercury was determined by automatic mercury analyzer(DMA-80). The contents of lead, cadmium, mercury, arsenic, chromium and nickel in samples were determined. The contents of lead was 0.0010-0.0572 mg/kg, cadmium was 0.0031-0.1009 mg/kg, mercury was 0.0001-0.0421 mg/kg, arsenic was 0.028-0.244 mg/kg, chromium was 0.016-0.495 mg/kg and nickel was 0.027-0.608 mg/kg, respectively. The Limit of detection(LOD), Limit of quantification(LOQ) and correlation coefficient(R2) for heavy metals(Pb, Cd, Hg, As, Cr and Ni) were 0.38-0.66 μg/kg, 1.21-2.09 μg/kg and 0.9999-1.0000, respectively. The recovery results and coefficient of variations were in the range 91.3-103.5% and 2.82-4.50%, by tested certified reference materials(CRM) and spiked standard solutions. For risk assessment, daily intakes of heavy metals were calculated and compared with provisional tolerable weekly intake(PTWI) or provisional tolerable monthly intake(PTMI) established by the Joint FAO/WHO Expert Committee on Food Additives(JECFA). Therefore, the level of overall dietary exposure to heavy metals for Korean through from these results, conforming with increase of milling degree of rice, heavy metal concentration tended to decrease. The contents of heavy metal were decreased 57.7% in lead, 13.0% in cadmium, 50.3% in mercury, 38.2% in arsenic, 59.1% in chromium and 48.5% in nickel in according to the highest milling degree of 9.6%(polished rice). The reduction rate of heavy metals were as Cr>Pb>Hg>Ni>As>Cd.
국내 다소비 농산물의 알루미늄 농도 모니터링 및 농산물 섭취로 인한 위해도 평가
안재민 ( Jae Min An ),홍경숙 ( Kyong Suk Hong ),김성연 ( Sung Youn Kim ),김지혜 ( Ji Hye Kim ),유경은 ( Kyong Eun Yu ),김효영 ( Hyo Young Kim ),박형달 ( Hyoung Dal Park ),이재훤 ( Jae Hwon Lee ),김동호 ( Dong Ho Kim ) 한국환경농학회 2015 한국환경농학회지 Vol.34 No.4
BACKGROUND: This study was carried out to collect occurrence data on aluminum in 12 type agricultural products and assess dietary exposure risk to the Korean population health for aluminum concentration in agricultural products.METHODS AND RESULTS: Aluminum analysis samples were performed using microwave device and Inductively Coupled Plasma Optical Emission Spectrometer. The LOD(Limit of Detection) for aluminum was 0.851 ug/kg,while the LOQ(Limit of Quantitation) was 2.838 ug/kg and recovery was 97.6% for aluminum. The average levels of aluminum in mg/kg were 0.526 for rice, 0.546 for Korean cabbage, 1.316 for corn, 6.207 for soybean, 0.549 for sweet potato, 0.257 for potato, 6.963 for spinach, 1.213 for carrot,0.524 for garlic, 0.950 for radish, 1.015 for leek, and 3.511 for Welsh onion. The dietary exposures of aluminum through usual intake were polished rice 89.31 ug/day,Korean cabbage 33.14 ug/day, corn 0.66 ug/day, soybean 3.72 ug/day, sweet potato 6.86 ug/day, potato 4.96 ug/day,spinach 45.96 ug/day, carrot 6.79 ug/day, garlic 2.36 ug/day, radish 7.32 ug/day, leek 2.23 ug/day and Welsh onion 43.89 ug/day, taking 0.57%, 0.21%, 0.00%, 0.02%,0.04%, 0.03%, 0.04%, 0.04%, 0.02%, 0.05%, 0.01% and 0.28% of PTWI(2 mg/kg b.w./week), respectively.CONCLUSION: The levels of overall dietary exposure to aluminum for Korean population through intake of agricultural product was far below the recommended JECFA level, indicating of least possibility of risk.
Tacrolimus를 근간으로 한 면역억제제를 복용하는 장이식 환자에서 이식 후 새로 발생한 당뇨병의 위험인자
허우성 ( Woo Seong Huh ),최유경 ( Yu Kyong Choi ),김예지 ( Ye Jee Kim ),최남경 ( Nam Kyong Choi ),김민영 ( Min Young Kim ),백나나 ( Na Na Baek ),염지연 ( Ji Youn Youm ),이정은 ( Jung Eun Lee ),김대중 ( Dae Joong Kim ),김윤구 ( Yoo 대한신장학회 2010 Kidney Research and Clinical Practice Vol.29 No.6
Purpose: This study was conducted to identify risk factors for new onset diabetes after transplantation (NODAT) among renal transplant recipients treated with tacrolimus-based immunosuppressant. Methods: We selected renal transplant recipients who underwent surgery at Samsung Seoul Hospital between May 2001 and July 2009. Exclusion criteria were as follows: recipients <18 years old, history of diabetes mellitus (DM) or impaired glucose tolerance. Analysis of possible risk factors for NODAT included age, gender, body mass index, co-morbid diseases, family history of DM, infection of hepatitis B or polyomavirus, type of donors (cadaver or living) and acute rejection. Overall incidence and median value of NODAT onset day were analyzed with Kaplan-Meier curve. We calculated crude incidence rate and relative risk (RR) and 95% confidence interval (CI) for independent risk factors of NODAT using Cox proportional hazard analysis. Results: A total of 278 patients were included and the incidence of NODAT was 13.3% (5.6/100 person-year) and the median duration of NODAT onset was 28 days. In Cox analysis, risk factors for NODAT were age (45-59 years: RR=1.41, 95% CI 1.09-1.83, 60> years: RR=4.36, 95% CI 2.00-9.49), family history of DM (RR=1.62, 95% CI 1.12-2.34) and polyomavirus infection (RR=1.40, 95% CI 1.08-1.81). Conclusion: The risk factors for NODAT among renal transplant recipients treated with tacrolimus- based regimen were age (>45 years old), family history of DM and polyomavirus infection.