수세미오이(Sponge-gourd: Luffa cylindrica L.) 추출물의 항산화, 항돌연변이 및 암세포 증식 억제 효과

오세인,이미숙,Oh, Se-In,Lee, Mee-Sook 한국식품영양학회 2012 韓國食品營養學會誌 Vol.25 No.4

Considering the dearth of information regarding the medicinal properties of Luffa cylindrica, we assessed the antioxidative, antimutagenic and hyperplasia inhibitory activity of cancer cells from Luffa cylindrica extracts by employing biological and biochemical assays. Ethanol extracts of Luffa cylindrica inhibited MDA-BSA (malondialdehyde-bovine serum albumin) conjugation reaction ($66.38{\pm}2.65$), DPPH (1,1-diphenyl-2-picryl-hydrazyl) radical production ($60.13{\pm}0.42$) and lipid peroxidation ($56.04{\pm}3.24$). In this study, Luffa cylindrica is believed to exert possible antioxidative effects. The direct and indirect antimutagenic effects of the ethanol extracts of Luffa cylindrica were examined by the Ames test using Salmonella typimurium TA98 and TA100. The inhibitory effects on indirect and direct mutagenicity shows an weak tendency, particularly in direct mutagenicity mediated by 2-nitrofluorene in Salmonella typimurium TA98 ($5.82{\pm}5.74$) and in indirect mutagenicity mediated by 2-anthramine in Salmonella typimurium TA100 ($5.76{\pm}2.15$). The ethanol extracts of Luffa cylindrica on cancer cell hyperplasia inhibitory activity via MTT (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide) assay exerted cytotoxic effects on Hela cells ($55.83{\pm}3.83$) and MCF-7 cells ($33.03{\pm}2.09$), which were used in this study. Based on these results, it believed that the ethanol extracts of Luffa cylindrica have antioxidative capacities as well as hyperplasia inhibitory activity of cancer cells. Furthemore, Luffa cylindrica is a candidate for the prevention and dietetic treatment of chronic diseases and for the development of functional food.

전라북도 순창지역 노인의 건강 및 영양섭취 실태

오세인,이미숙,Oh, Se In,Lee, Mee Sook 한국식품영양학회 2019 韓國食品營養學會誌 Vol.32 No.3

The objective of this study was to investigate the health status and nutritional intake of the old population living in Soonchang, Jeollabuk-do, Korea. 69 subjects aged 65 years and older were recruited in July 2016. The WHR, was significantly higher in elderly male group than elderly female group (p<0.05), but both groups had abdominal obesity (0.85 and over). T-score mean of elderly male and female groups were below $-2.5mg/cm^3$ that they were osteoporotic. In the elderly male group, the higher concentrations of creatinine, homocysteine and uric acid were found to be significantly unfavorable factors (p<0.001, respectively). The blood vitamin $D_3$ levels of elderly male group was significantly higher than that of elderly female group (p<0.05). The physical activity and self-rated health were significantly higher in elderly male group than in elderly female group (p<0.05, p<0.01, respectively). The nutrient intakes of male group were found to be significantly favorable factors than in female group. The score of mini nutrition assessment was significantly lower in elderly female group than in the elderly male group. These results could be useful to plan effective strategies to increase the health-life expectancy and the prevention of disease of Korean elderly people living in rural areas.

전라도 장수지역에 거주하는 여자노인의 동거유형에 따른 생화학적 지표 및 영양섭취상태에 관한 연구

오세인,곽충실,연미영,이미숙,Oh, Se In,Kwak, Chung Shil,Yon, Miyong,Lee, Mee Sook 한국식품영양학회 2014 韓國食品營養學會誌 Vol.27 No.5

The purpose of this study was to compare the degree nutrient intake, health status and other characteristics of females aged 65 years and over in a longevity area according to family arrangement. For analysis, 585 female elderly were recruited from the Kugoksoondam area (Kurye, Goksung, Soonchang and Damyang counties), known as the longevity-belt region in Jeonla province, Korea. The subjects were categorized into three groups according to family arrangement (living alone, living with spouse only and living with family). Demographic characteristics were collected, as well as information on physical measurements, blood tests for biochemical indicators, health status and health-related life style, dietary behavior, favorite food groups, consumption frequency of food groups, nutrient intake and mini nutrition assessment. In the group living with their spouse only, the highest education, physical activity, diverse food intake, frequency of eating meats and fish, energy and nutrients intake, and score on the mininutrient status assessment (MNA) were found to be significantly favorable factors. Taken together, these results demonstrated that the group living with their spouse only had relatively superior nutrient intake and the quality of diet. In contrast, the group living alone showed the lowest self-rated economic status, diversity of food intake, and physical activity, with the highest frequency of drinking, smoking and regular exercise for almost everyday compared with the other groups. On the other hand, those living with family demonstrated the lowest intake of supplements or functional foods, and levels of hemoglobin hematocrit MCH, but the highest HBA1c and blood sugar. Therefore, the group living with family was assumed to be at risk of anemia and diabetes. These results could be useful to plan effective strategies to increase the health-life expectancy of Korean elderly people living in rural areas, according to family arrangement.

전라도에 거주하는 여자노인의 당화혈색소 수준에 따른 건강위험인자의 비교분석 - 생화학적 요인, 식습관 및 영양상태 -

오세인,곽충실,이미숙,Oh, Se In,Kwak, Chung Shil,Lee, Mee Sook 한국식품영양학회 2016 韓國食品營養學會誌 Vol.29 No.3

The purpose of this study was to investigate the relations between HbA1c level and health risk factor. For analysis, 330 elderly women aged 65 years and over were recruited in Jeonla province, Korea. The subjects were classified into two groups according to their HbA1c level; the diabetic group (HbA1c level${\geq}6.5%$, n=68, 20.6%) and control group (HbA1c level<6.5%, n=262, 79.4%). Demographic characteristics were collected, as well as information on physical measurements, blood tests for biochemical indicators, a health status and health-related life style, dietary behavior, favorite food groups, consumption frequency of food groups and nutrient intake. Educational level of the diabetic group was significantly lower than that of the control group. The height of the diabetic group was shorter, and percentage fat of the diabetic group was higher than those of the control group. In the diabetic group, the higher concentrations of creatinine and activity of alkaline phosphatase were found to be significantly unfavorable factors. Therefore, the diabetic group was assumed to be at risk of decreased liver and renal function. The self-rated health level of the diabetic group has a declining tendency, while the medicine intake was significantly higher than that of the control group, but there are no significant differences in visiting frequency of hospital and community health center. The distribution of physical activity showed a significant difference between the groups. Although there are no significant differences in nutrient intake, the diabetic group had relatively inferior nutrient intake of diet, especially vitamin C, as contrasted with the control group. In conclusion, the weight control and increasing physical activity may be effective in the prevention of the diabetes and continuous education and intervention by specialized nutritionists will be needed for diabetic patients. These results could be useful to plan effective strategies to increase the health-life expectancy and the prevention of the diabetes of Korean elderly people living in rural areas.

전라도 장수지역에 거주하는 여자노인의 골밀도에 따른 생화학적 지표 및 영양섭취상태에 관한 연구

오세인,곽충실,이미숙,Oh, Se In,Kwak, Chung Shil,Lee, Mee Sook 한국식품영양학회 2015 韓國食品營養學會誌 Vol.28 No.2

This study was conducted to investigate the dietary and other factors affecting bone mineral density (BMD) in older Korean women. A total of 340 women aged 65 to 74 were recruited from the Kugoksoondam area (Kurye, Goksung, Soonchang and Damyang counties), known as the longevity-belt region in Jeonla province, Korea. They were categorized into two groups according to bone status by T-score : a nonosteoporotic group and an osteoporotic group. Demographic characteristics were collected, as well as information on physical measurements, blood tests for biochemical indicators, health status health-related life style, dietary behavior, favorite food groups, nutrient intake and mini nutrition assessment (MNA). The results are as follows: The mean age of 185 nonosteoporotic women was 69.6 years and that of 155 osteoporotic women was 70.9 years (p<0.001). The mean T-score of the nonosteoporotic group was $-1.5mg/cm^3$ and that of theosteoporotic group was $-3.2mg/cm^3$ (p<0.001). Height and body weight in the nonosteoporotic group were significantly higher than in the osteoporotic group (p<0.001, respectively). There was no significant difference in BMI, although the BMI in the nonosteoporotic group was slightly higher. Waist and hip circumferences in the nonosteoporotic group were significantly higher than in the osteoporotic group (p<0.01, respectively), and the mid upper arm and calf circumferences were also significantly higher than in the osteoporotic group (p<0.001, p<0.01, respectively). The 5 m walking ability was significantly superior compared to the osteoporotic group. Serum levels did not show any significant differences between the groups and were within normal range. The serum total protein, albumin and Insulin-like growth factor (IGFs) levels of the nonosteoporotic group were significantly higher than those of the osteoporotic group (p<0.05, p<0.05, p<0.001, respectively). IGF was 104.7 ng/mL for the nonosteoporotic group and 88.1 ng/mL for the osteoporotic group. Physical activity and appetite in the nonosteoporotic group were significantly higher (p<0.01, p<0.05, respectively). The favorite food groups of the nonosteoporotic group comprised more meats and fish than those of the osteoporotic group (p<0.05, respectively). Nutrient intake was not significantly different, with the exception of niacin intake (p<0.05), but the nutrient intake of the nonosteoporotic group was slightly higher than that of the osteoporotic group. The niacin intake of the nonosteoporotic group and the osteoporotic group were 11.4 mgNE and 10.0 mgNE, corresponding to 103.6% and 90.9% of the Korean EAR, respectively. The MNA score of the nonosteoporotic group was significantly more favorable than for the osteoporotic group. In conclusion, it is necessary to maintain adequate body weight and muscle mass. Habitual physical activity may have a beneficial effect on BMD for older women. Dietary factors, such as meat and fish, higher intake of niacin rich foods and nutrient status for older women also appear to have favorable effects on bone mineral density.

식민지적 디아스포라와 유랑 의식 : 김소월, 이상화, 오장환의 시를 중심으로

오세인(Oh Se-In) 중앙어문학회 2010 語文論集 Vol.45 No.-

This paper considers 'wandering consciousness' of Kim, So-wol, Lee, Sang-hwa and Oh, Jang-hwan's Poetry as the expression of 'colonial diaspora'. Also, by including colonial particularities in the discussion of diaspora, it aims to enrich the existing concept of diaspora. Until now, studies on diaspora in the Western and Korean academia have mainly focused on disposition of space and identity, without considering particularities of the colonized. The colonized perceive their place of residence as a place belong to the mainland of the colonizer because of the fact that they lost their country, material and mental sense of alienation, political and economical discrimination, etc. This is diasporic in that it leads them to consider their country before the colonization as symbolic homeland and the land which they should regain. Kim, So-wol and Lee, Sang-hwa described wandering consciousness of the subject who lost its destination because of oppression and discrimination by the colonizer. Paek, Seok and Lee, Yong-ak tragically depicted the life of Koreans who had to leave homeland and wandered about the northern region. By portraying the life of sailors who wandered about the stateless space(harbour), Oh, Jang-hwan expressed the colonial subject's wandering consciousness, that is, 'colonial diaspora consciousness'.

현대문학 : 1920년대 초중반 "거리(街)"의 문학적 표상화 과정 연구

오세인 ( Se In Oh ) 배달말학회 2012 배달말 Vol.50 No.-

이 논문은 근대 초기 ``거리``가 중요한 사회적, 문학적인 표상으로 등장하는 이유와 과정을 밝히기 위해 1920년대 초중반 신문 기사와 문학 비평, 그리고 수필에서 ``거리(街)``를 묘사하는 방식을 살펴보았다. 폭력성과 차별에 대한 표상 공간으로서의 ``거리``에 대한 당대의 주목은 근대 주체들이 ``식민지 자본주의 도시``라는 새로운 체제와 질서에 대한 비판적 인식을 ``거리``의 표상화를 통해 드러내려 했음을 보여준다. 2장에서는 거리를 다룬 신문 기사를 살펴보았다. 당시 기사에서 거리는 ``유랑민``과 ``걸인``의 비참한 삶이 목격되는 공간이었다. 경성의 거리에 ``유랑민``과 ``걸인``이 점점 증가하고 있다는 기사는 식민지 근대 도시화가 불러온 빈곤과 유랑의 문제를 사회적 현상으로 인식하는 계기가 되었다. 신문 기사는 거리를 당대의 구조적 모순에 기인한 문제적 현상이 나타나는 ``공간 표상``으로 전유함으로써 그에 대한 사회적 인식을 이끌어내려 했음을 밝혔다. 3장에서는 거리로 나아갈 것을 주장하는 문학 비평을 살펴봄으로써 거리가 민중의 ``참생활``이 펼쳐지는 상징적 공간으로 표상화되고 있음을 밝혔다. 당대의 문인들이 거리로 나아갈 것을 주장한 이유는 지금까지의 문학이 거리의 현실, 즉 조선인의 삶을 제대로 반영하지 못했다고 생각했기 때문이었다. 문학 비평에서 거리는 삶의 현장이라는 상징성을 갖게 되며 조선 민중의 ``참생활``을 관찰하고 경험함으로써 문학적으로 형상활 수 있는 이데올로기적 실천의 공간으로 표상화되었다. 4장에서는 거리를 묘사한 김기진의 수필을 살펴보았다. 김기진은 수필에서 거리에서 목격한 조선 민중의 비참한 삶을 묘사함으로써 거리를 식민지 자본주의적 질서가 실현되는 공간으로 표상화시켰다. 그의 수필에서 거리는 매혹과 차별이라는 식민지 자본주의 근대의 이중적 질서가 실현되는 공간이다. 김기진은 거리가 식민지 자본주의 도시의 본질을 드러내는 공간임을 인식하고 거리를 그 본질적 모순과 이중성에 대한 표상으로 삼았다. 거리는 자본주의적 질서가 개별 주체에게 가하는 폭력성과 차별이 생생하게 드러나는 현장이라는 점에서 근대 사회의 형성 이후 오늘날까지 문학에서 중요하게 다루어져 왔다. 근대 초기 거리가 중요한 사회적이고 문학적인 표상으로 등장하게 되는 과정을 보다 면밀히 살펴보기 위해서는 1910년대 후반의 신문 및 잡지 기사, 창가와 신체시 등 다양한 담론의 형식들을 살펴보아야 할 것이다. 이에 대한 연구는 후고를 기약한다. This paper aims to clarify the process in which ``street`` emerges as an important social and literary representation in early modern Korea by examining articles of newspapers, literary criticisms and essays in the first half of the 1920s. Observation on street as the representational space of violence and discrimination shows that modern subjects attempted to reveal their critical recognition for the new system, colonial capitalist city through the representation of ``street``. In chapter 2, this article looked through newspaper articles. They described street as the place where poor Korean people were wandering. By appropriating street as the space representation in which social phenomena caused by structural contradictions, newspaper articles requested the social recognition for the phenomena. In chapter 3, it clarified that street was becoming the representation of symbolic space where the real life of common people was unfolded. Critics of the period argued that they should go onto the street. In their literary criticisms, street was described as the space where class awakening and practical movement were required and it became the ideological and national symbol and representation. Chapter 4 analyzed Kim, Gi-jin`s essays describing tragic life of Korean people on the street. He represented the street as the space where colonial capitalist order, attraction and discrimination was practiced. He recognized that the street was the space where the the essence of the colonial modern city was revealed and described it as the representation of contradiction and duality of the period.

표고버섯 에탄올 추출물의 산화적 스트레스 억제 효과와 항돌연변이 효과

오세인 ( Se In Oh ),이미숙 ( Mee Sook Lee ) 한국식품영양학회 2007 韓國食品營養學會誌 Vol.20 No.4

DRagon(Design & Reuse)시스템을 위한 객체 다이어그램의 스타일 가이드

오세인(Se-In Oh),한규정(Kyu-Jung Han),변상용(Sang-Yong Byun),이경환(Kyung-Whan Lee) 한국정보과학회 1990 한국정보과학회 학술발표논문집 Vol.17 No.1

본 연구는 소프트웨어 재사용을 객체 지향 개발(Object Oriented Development)에 기반을 둔 DRagon (Design & Reuse) 시스템의 구성 부분인 다이어그램 기법을 제안한다. 본 다이어그램은 객체 지향 메카니즘을 연구 분석하여 시스템 설계시 사용되는 다이어그램의 표현 영역을 확장시켰다. 아울러 개발된 다이어 그램은 재사용 라이브러리에 분류 저장되어 시스템 개발자가 원하는 컴포넌트의 구성을 시각적으로 검색, 확인할 수 있는 능력을 제공한다.

전통 장류의 염도 및 당도가 농촌 노인의 맛 감지도와 식품섭취행태에 미치는 영향

오세인 ( Se In Oh ),이미숙 ( Mee Sook Lee ) 한국식품영양학회 2017 韓國食品營養學會誌 Vol.30 No.4

The consumption of high-salt foods is an independent risk factor for increased hypertension. Thus, evaluating the relationship of taste sensitivity and pleasantness of high-salt foods such as Korean jang products, would help contribute to an understanding of salty food eating behaviors of the Korean rural elderly. This study aimed to verify the association between taste sensitivity and salinity of Korean jang products, and the preferences of food groups and nutrient intake in the rural elderly. We studied 269 elderly persons (males 83, females 186) aged above 65 years, residing in the rural area, Sunchang gun Jeonbuk. For each subject, a recognition threshold of 4 basic tastes and pleasant concentrations of NaCl were estimated using the sip- and-spit method. Taste preferences, frequency of intake of food groups, nutrient intakes, and salinity and sweetness of Korean jang products (Doenjang, Ganjang, Gochujang) were assessed. No association was found between salt taste recognition threshold and optimally preferred concentration of salt and salinity of Korean jang products. However, the sweet taste recognition threshold was positively related to the sweetness of Korean jang products. Also, the salinity of Doenjang positively correlated with the frequencies of food groups and nutrient intakes. That is to say that the sweet taste sensitivity was related to the sweetness of Korean jang products, but was not sensitive to the salty taste. The salinity of Doenjang correlated with the consumption of food and nutrient intakes. Taken together, these findings suggest the need for appropriate intervention and education to reduce the salinity of Doenjang, which is an important modifiable factor contributing to reducing sodium intake in the rural elderly.