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골 임파종에 대한 방사선 조사 부위에 발생한 이차성 직장암 1예
엄민식,이홍기 인제대학교 2006 仁濟醫學 Vol.27 No.-
Radiotherapy (RT) has been used for many years, as a primary or additional tool in cancer treatment, but it has also been associated with the risk of developing another cancer. Although bone and soft tissue sarcomas are the most frequent second neoplasia following RT, Rectal cancer also can be occurred after pelvic radiotherapy. In this report, we present a patient with rectal cancer, which was developed at the same site where the patient used to get the RT, due to primary bone lymphoma. A 42-years-old man was diagnosed as a malignant lymphoma on the left hip in June 1996. His clinical stage was I_(BE). He received concurrent chemoradiotherapy; Radiotherapy, which was held with the dose of 61 Gy to femoral head, acetabulum and ischial tuberosity. And Chemotherapy was CHOP(cyclophosphamide, doxorubicin, vincristine, and prednisolone). One month later, the patient was presented with hematochezia due to radiation proctitis, and the symptom was soon improved with symptomatic treatment. He received regular follow-up at outpatient basis. In April 2003, he visited our hospital for the evaluation of constipation and anal pain for 2 months. Colonoscopy showed obstructive mass lesion at 10cm apart from anal verge and the biopsy has been revealed as adenocarcinoma. The computed tomography (CT) scan of pelvis showed the circumferential wall thickening of upper rectum with blurring margin. He has received 3 cycles of neoadjuvant chemotherapy with leucovorin and 5-FU in combination and then lower anterior resection with colostomy. The pathologic stage was Ⅲb (T3N1). Additional 6 cycles of adjuvant chemotherapy were administered. He has been in remission for 9 months after operation.
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엄민식,박원우,서승철,이진호,조주연,최혜영,이찬희,임소덕 白中央醫療院 2005 仁濟醫學 Vol.26 No.1
Relapsing polychondritis is an uncommon multisystemic disease which is characterized by recurrent episodes of inflammation and progressive destruction of cartilaginous tissue. The cause of relapsing polychondritis is unclear and suspected to be autoimmune pathophysiology. It involves cartilage of nose, vertebra, trachea, peripheral joint as well as structures of eye, heart, blood vessels or inner ear. Auricular chondritis is present in almost all patients, and multiple arthritis, nasal chondritis, saddle nose, eye involvement, laryngotracheal involvement and skin manifestations are also present. We report a case of relapsing polychondritis presented a arthritis with review of literatures.
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