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RISS 인기검색어
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- 저자 : 양형국(Hyung Kook Yang) (검색결과 5 건)
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유기용제 흡입중독후 의식소실로 발생한 중증의 저체온증 치유 1례
양관모 ( Kwan Mo Yang ),권태욱 ( Tae Wook Kwon ),김형국 ( Hyung Kook Kim ),박규남 ( Kyu Nam Park ),김세경 ( Se Kyeung Kim ) 대한응급의학회 1997 대한응급의학회지 Vol.8 No.2
A 19-year-old man had a good neurologic recovery from a severe hypothermia(19C) and a prolonged coma following active intemal rewarming. From inhaling hydrocarbons, he was left unconscious on the cold floor for 24 hours. As soon as the patient was brought into the emergency medical center, he was early evaluated and treated aggressively. 'ECG showed Osborn(J) wave on all leads. The temperature of patient was increased by 2-3C per hour through active external rewarming (by heating blankets and warm bag) and active intemal rewarming (by airway rewarming, warmed IV fluids, gastrointestinal tract irrigation, and bladder irrigation). The temperature reached 36C after 6 hours. Active internal rewarming provides rapid core rewarming with the additional benefit of circulatory support during the period of cardiac instability.
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데페록사민 전처치가 토끼 심근경색 크기의 감소에 미치는 효과
양관모,오동렬,박승현,박규남,이원재,김형국,황두영,최승필,채장성 대한응급의학회 1998 대한응급의학회지 Vol.9 No.4
Background: Reperfusion of ischemic myocardium has been postulated to result in a specific oxygen radical mediated tissue injury. Iron may liberate during ischemia and we hypothesized that administration of the iron chelator, deferoxamine during ischemia would result in improved recovery after postischemic reperfusion. Purpose: To test whether iron-catalyzed processes contribute to myocardial necrosis during ischemia and reperfusion, deferoxamine was administered to block iron catalyzed hydroxyl radical formation in rabbits. Methods: Eleven rabbits were divided into two groups : control group (n=5) and deferoxamine pretreatment group (n=6). The left circumflex coronay artery was ligated for 30 minutes and reperfused for 180 minutes. Area at risk (AR) was measured by non-stained area with methylene blue injection into left atrium after left circumflex coronary artery ligation. Infarct size was measured by weighing after triphenyltetrazolium chloride staining. Heart rate was measured using electrocardiographic recording and systemic blood pressure was monitored by pressure transducer connected to the catheter in the left ventricle. Results: 1. There was no significant difference of heart rate and blood pressure in deferoxamine pretreatment group compared with control group. 2. There was significant decrease of serum iron concentration after continuous infusion of deferoxamine compared with serum iron concentration before ligation of coronary artery(P<0.05). 3. There was no significant difference of area at risk between control and deferoxamine pretreatment group. 4. Area at necrosis to area at risk was significantly reduced in deferoxamine pretreatment group compared with control group(P<0.05). The results suggest that deferoxamine infusion prior to coronary artery occlusion has a significant benefit in reducing infarct size in this model.
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Nitrous Oxide 농도에 따른 진통효과와 혈역학적 변화에 대한 비교 관찰
이운정,김형국,양관모,유은영,나병호,이원재,박규남,권태욱,김세경 대한응급의학회 1997 대한응급의학회지 Vol.8 No.4
Background: Nitrous oxide is a safe analgesics which has analgesic and sedative effects without loss of consciousness. The advantage of Nitrous oxide is that it has a rapid onset time and that we can modulate duration of its action. The purpose of this experiment is to obtain the safe and effective concentration of Nitrous oxide in Emergency Department as use of analgesics and sedative drugs. Methods: Twenty volunteers were investigated according to double blind method Nitrous oxide was administrated to volunteer subjects at different concentrations ; 33%, 50%, 67% each. Then we evaluated the Pain score, Blood pressure, Heart rate, Respiratory rate, Oxygen saturation and its side effects. Results: Pain Score were 8.4 ±2.1 at 33% 6.1 ±1.5 at 50% and 3.65 ±2.2 at 67% of Nitrous oxide. Pain Score is decreased significantly following administration of Nitrous oxide at concentration of 50%, 67%(p<0.05). There was no difference between preadministration group and postadministration group. While no remarkable change in systolic blood pressure, heart rate, and oxygen saturation. Respiratory rate showed significant increase when 67% of Nitrous oxide was administrated. There was no side effect in administration of 33% of Nitrous oxide. When 50% of Nitrous oxide was administrated, there were dizziness 5(25%), paresthesia 2(10%), nausea 1(5%), palpitation 1(5%), and hyperethesia 1(5%). At 67% of Nitrous oxide, there were nausea 7(35%), dizziness 6(30%), paresthesia 5(25%), headache 5(25%), diplopia 2(10%), dysphoria 2(10%), salivation 1(5%), dyspnea 1(5%), nystagmus 1(5%), tinnitus 1(5%) and euphoria 1(5%). Incidence of side effect increased as the concentration of Nitrous oxide was increased. Conclusion: We can conclude that safe and effective concentration of Nitrous oxide is 50% as analgesics and sedative drugs in the emergency department.
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유기용제 흡입중독후 의식소실로 발생한 중증의 저체온증 치유 1례
박규남,김형국,양관모,권태욱,김세경 대한응급의학회 1997 대한응급의학회지 Vol.8 No.2
A 19-year-old man had a good neurologic recovery from a severe hypothermia(19℃) and a prolonged coma following active internal rewarming. From inhaling hydrocarbons, he was left unconscious on the cold floor for 24 hours. As soon as the patient was brought into the emergency medical center, he was early evaluated and treated aggressively. ECG showed Osborn(J) wave on all leads. The temperature of patient was increased by 2-3℃ per hour through active external rewarming (by heating blankets and warm bag) and active internal rewarming (by airway rewarming, warmed IV fluids, gastrointestinal tract irrigation, and bladder irrigation). The temperature reached 36℃ after 6 hours. Active internal rewarming provides rapid core rewarming with the additional benefit of circulatory support during the period of cardiac instability.
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