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안현주,허란희,김민정,조은정,한현주,손인자 韓國病院藥師會 2004 병원약사회지 Vol.21 No.3
This study is an attempt to investigate on the substitution of outpatients prescriptions dispensed in SNUH(Seoul National University Hospital) after launching the prescription-drug dispensing separation system in Korea. Out of the outpatient prescriptions issued in SNUH from July 2000 to September 2003, those substituted were chosen for the study. The percentage of prescriptions which were substituted and the rate for drug substitution which were not allowed has been on the decrease as the prescription-drug dispensing separation steadily gained its ground. Medicine most substituted at the pharmacies are diazepam, atenolol, furosemide, amitriptyline in order of frequency. The rate of substitution of prescriptions was highest in the department of plastic surgery, with the departments of neuropsychology, emergency, diagnostic radiology following. When substituting prescriptions, pharmacists sometimes failed to report the amount of the dispensed medicine(37%), the date of the prescriptions(14%), the name of the pharmacy(8%) and the pharmacist(7%). 29% of the substitution appeared to be done at the pharmacies located around SNUH, and 69% at the other pharmacies. We found examples of the reports not being made properly when substitutions were done to some degree. Also it was difficult to control the malpractice. And to improve this situation, some measures and efforts should be taken by pharmacies, pharmaceutical companies, and the government authorities.