http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
황영민,이진실,안하정,오혜련,성대경,태기융,최원일 한국공업화학회 2021 Journal of Industrial and Engineering Chemistry Vol.104 No.-
We previously developed an injectable levan-based hydrogel as a temporary dermal filler. However, thelongevity and collagen stimulation effect of the levan-based hydrogel were limited. Herein, we preparedhydroxyapatite (HAp)-embedded levan composite hydrogel as a long-acting dermal filler for enhancingin vivo collagen production and anti-wrinkle efficacy. HAp amount (0.1–5 wt%) in the levan hydrogelwas optimized for stability, safety, and efficacy. Increasing the HAp amount decreased the in vitro stabilityand elastic modulus, but the composite hydrogel structure was still maintained. Furthermore, thecomposite hydrogel showed improved cell proliferation stimulation compared to the bare levan hydrogelin human dermal fibroblast cells. In vivo stability of the composite hydrogel was enhanced in contrast tothe in vitro result, showing stable residence of the composite hydrogels with 0.5 or 1 wt% HAp over8 weeks. Moreover, the excellent anti-wrinkle efficacy of composite hydrogel with 1 wt% HAp was maintainedduring 8 weeks and it showed the highest collagen production. Thus, HAp-embedded levan compositehydrogel showed potential as a dermal filler with easy injectability, biocompatibility, and longactinganti-wrinkle efficacy.
박과식물의 발아와 당 신생 관련 유전자의 발현 특성에 관한 탐구
김민규 ( Min Gyu Kim ),김예은 ( Ye Eun Kim ),송지현 ( Jee Heon Song ),안하정 ( Ha Jung Ahn ),임범혁 ( Buem Hyuk Yim ),차형정 ( Hyun Jung Cha ),김대재 ( Dae Jae Kim ) 충북대학교 과학교육연구소 2014 과학교육연구논총 Vol.29 No.2
Here we report the investigation of gluconeogenic genes expression in oliseed plants during development of cucumber (Cucumis sativus L.) cotyledons. First, we looked at the ICL, gMDH and PCK genes expression which are related to glyoxylate cycle and gluconeogenesis in cucumber germination. Cucumber cotyledon development classified to three stages: germination, growth and senescence. Germination of cucumber shows unique metabolic mobilization of reserved lipids to sugars for establishment of post-germinative growth just before the photo autotropic growth. Senescence appears as the final development in cotyledon too. The genes are also expressed in the final senescence development. We looked at the genes expression through the RT-PCR approach. As the results, ICL and PCK genes were expressed both germination and leaf senescence but gMDH is not for sure.