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최숙근 ( Suk Keun Choe ),이신화 ( Shin Wha Lee ),정의 ( Eui Jung ),오지영 ( Jee Young Oh ),김선권 ( Sun Kwon Kim ),심재윤 ( Jae Yoon Shim ),원혜성 ( Hye Sung Won ),이필량 ( Pil Ryang Lee ),김암 ( Ahm Kim ) 대한산부인과학회 2005 Obstetrics & Gynecology Science Vol.48 No.3
Multiple pterygium syndrome is an inherited condition characterized by joint pterygium and flexion contracture, in association with other abnormalities such as fetal hydrops, cystic hygroma, club foot, intrauterine growth retardation and hypoplastic lungs
임신 중 위암의 전이성 난소 병변과 동반된 가성 메이그스 증후군
유래미 ( Rae Mi You ),신유정 ( You Jung Shin ),김민균 ( Min Gyun Kim ),심재윤 ( Jae Yoon Shim ),원혜성 ( Hye Sung Won ),이필량 ( Pil Ryang Lee ),김암 ( Ahm Kim ) 대한산부인과학회 2010 Obstetrics & Gynecology Science Vol.53 No.7
Pseudo-Meigs` syndrome is a syndrome that includes hydrothorax and ascites secondary to ovarian tumors other than solid benign fibroma. In this report, we present the case of a 29-years-old female who complained of abdominal distension with peripheral edema during her third trimester. Two solid masses of 15 cm dimension in the left abdomen and 7 cm dimension in the right abdomen were detected by ultrasound and chest X-ray revealed right pleural effusion. Magnetic resonance imaging (MRI) confirmed the ovarian masses and ascites. As the patient had regular uterine contractions, we decided to perform emergency cesarean section because of previous cesarean section history. A laparotomy was performed and pathologists confirmed the presence of a metastatic adenocarcinoma. Four days following the surgery, gastroduodenoscopy revealed a huge ulcerofungating mass was visible in greater curvature of stomach. The final diagnosis was metastatic adenocarcinoma from gastric cancer. Although pseudo-Meigs` syndrome is very rare, it should be carefully considered when evaluating female complaining with ascites in ovarian tumor.
조기분만진통 환자의 산전 자궁내 감염 및 주산기 예후 예측에 관한 양수내 Monocyte Chemotactic Protein - 1 측정의 유용성
심순섭(Soon Sup Shim),박현수(Hyun Soo Park),임준희(June Hee Lim),심재윤(Jae Yoon Shim),천대우(Dae Woo Chun),박중신(Joong Shin Park),전종관(Jong Kwan Jun),윤보현(Bo Hyun Yoon),신희철(Hee Chul Syn) 대한산부인과학회 2002 Obstetrics & Gynecology Science Vol.45 No.6
목적 : 양막파수가 없는 조기진통 산모에서 양수내 monocyte chemotactic protein-1 (MCP-1) 농도가 자궁내 감염과 임신 예후를 평가하는 데 유용한지 알아보고자 하였다. 연구 방법 : 양막파수가 없는 조기진통으로 양수검사를 받은 65명을 연구 대상으로 하였다. 양수는 호기성, 혐기성 세균 및 마이코플라스마 배양을 시행하였다. MCP-1은 민감하고 특이적인 면역검사법으로 측정하였다. 통계적 분석에는 Fisher`s exact test, Mann-Whitney U test, receiver operating characteristic curve, 생존 분석법, logistic regression, Spearman correlation을 사용하였다. 결과 : (1) 양수 배양 양성인 환자에서 배양 음성인 환자에 비하여 양수내 MCP-1 농도의 중앙치가 유의하게 높았다 (median, 9.0 ng/mL; range, 0.45-40.5 ng/mL; vs median, 0.82 ng/mL; range, 0.06-30.1 ng/mL; P<.01). (2) 임신 주수를 보정한 후에도 양수내 MCP-1 농도가 1.9 ng/mL보다 큰 환자에서 1.9 ng/mL보다 작은 환자에 비하여 분만까지의 기간이 유의하게 짧았고 조직학적 융모양막염, 2일 및 5일 이내의 조산과 증명되거나 의심 되는 선천성 패혈증의 발생이 많았다 (P<.05). (3) 양수내 MCP-1 농도와 양수내 interleukin-6 농도 사이에는 강한 연관성을 보였다 (r=.881, P<.001). 결론 : 양막파수가 없는 조기진통 산모에서 양수내 MCP-1 농도 측정은 자궁내 감염과 조산, 신생아 감염성 합병증을 평가하는 데에 유용하다. Objective : To examine if amniotic fluid (AF) monocyte chemotactic protein-1 (MCP-1) concentrations are useful in the identification of intrauterine infection and pregnancy outcomes in preterm labor with intact membranes. Methods : The study population consists of 65 patients who received amniocentesis for preterm labor with intact membranes. Amniotic fluid was cultured for aerobic and anaerobic bacteria, as well as mycoplasmas. MCP-1 was determined by a sensitive and specific immunoassay. Fisher`s exact test, Mann- Whitney U test, receiver operating characteristic curve, survival techniques, logistic regression, and Spearman correlation were used for statistical analysis. Results : (1) Patients with a positive amniotic fluid culture had a significantly higher median AF MCP-1 concentration than those with negative results (median, 9.0 ng/mL; range, 0.45-40.5 ng/mL; vs median, 0.82 ng/mL; range, 0.06-30.1 ng/mL; P<.01). (2) Patients with AF MCP-1 concentration of >1.9 ng/mL had a significantly shorter median interval to delivery, the higher rate of histologic chorioamnionitis, preterm delivery within 2 and 5 days, and the occurrence of congenital proven or suspected sepsis than did those with AF MCP-1 concentration of <1.9 ng/mL after adjustment for gestational age (P<.05). (3) There was strong correlation between AF MCP-1 concentrations and AF interleukin-6 concentrations (r=.881, P<.001). Conclusion : AF MCP-1 determinations are useful in the identification of intrauterine infection, preterm delivery, and neonatal infectious complication in preterm labor with intact membranes.
복강경식 근치적 자궁경부절제술 이후 협부협착이 발생한 환자에서 협부확장술 시행 후 자궁강내 인공수정 시술을 통한 성공적인 임신 및 분만
임유진 ( You Jin Lim ),김정훈 ( Chung Hoon Kim ),김주연 ( Joo Yuen Kim ),권수경 ( Su Kyoung Kwon ),심재윤 ( Jae Yoon Shin ),김성훈 ( Sung Hun Kim ),채희동 ( Hee Dong Chae ),김용만 ( Yong Man Kim ),강병문 ( Byung Moon Kang ) 대한산부인과학회 2011 Obstetrics & Gynecology Science Vol.54 No.9
Uterine cervical cancer is one of the most common malignant disease in women, For young patients with early stage cervical cancer who want to preserve their fertility, radical trachelectomy is a promising fertility-sparing treatment in well-selected group of patients, However, isthmic stenosis is reported to occur in 15% of patients who received radical trachelectomy, Isthmic stenosis is one of causes of infertility following radical trachelectomy. In addition patients who underwent radical trachelectomy are at high risk of obstetric complications including preterm labor, premature rupture of membrane and preterm delivery. Herein we report a case of successful pregnancy and childbirth by intrauterine insemination following isthmic dilatation due to isthmic stenosis after laparoscopic trachelectomy with a brief review of the literature.
비면역성 태아수종: 임상양상과 신생아의 생존과 관련된 예후인자
이중엽 ( Joong Yeup Lee ),손유경 ( Yoo Kyung Sohn ),심순섭 ( Soon Sup Shim ),임준희 ( June Hee Im ),심재윤 ( Jae Yoon Shim ),박중신 ( Joong Shin Park ),전종관 ( Jong Kwan Jun ),윤보현 ( Bo Hyun Yoon ),신희철 ( Hee Chul Syn ) 대한산부인과학회 2002 Obstetrics & Gynecology Science Vol.45 No.12
목적 : 비면역성 태아수종의 발생빈도, 관련조건 (혹은 원인), 주산기 결과를 확인하고, 신생아 생존과 관련있는 예후인자를 밝혀내고자 하였다. 연구 방법 : 1988년 10월부터 2001년 2월까지 서울대학교병원 산부인과에서 진단된 54예의 비면역성 태아수종의 후향적 고찰을 통하여 발생빈도, 관련조건, 주산기 결과를 확인하였다. 아울러 생존하여 출산된 20예의 신생아를 28일 초과 생존한 군과 28일 이하에 사망한 군으로 구분하여 신생아 생존과 관련된 Objective : We undertook this study to find out clinical characteristics and prognostic factors of neonatal survival in nonimmune hydrops fetalis (NIHF). Methods : From Oct. 1988 to Feb. 2001, 54 cases of nonimmune hydrops fetalis diagnosed at Seoul Natio